Results 51 to 60 of about 406,601 (302)

Malaria

The Lancet, 2014
Although global morbidity and mortality have decreased substantially, malaria, a parasite infection of red blood cells, still kills roughly 2000 people per day, most of whom are children in Africa. Two factors largely account for these decreases; increased deployment of insecticide-treated bednets and increased availability of highly effective ...
White, N, White, N, Pukrittayakamee, S, Hien, T, Faiz, M, Mokuolu, O, Dondorp, A, Dondorp, A   +7 more
openaire   +4 more sources

The Economic Costs of Malaria in Children in three Sub-Saharan Countries: Ghana, Tanzania and Kenya. [PDF]

, 2013
Malaria causes significant mortality and morbidity in sub-Saharan Africa (SSA), especially among children less than five years of age (U5 children).
Sicuri, E, Constenla, Dagna, Dagna Constenla, Elisa Sicuri, Sicuri, Elisa, Vieta, Ana, Constenla, D, Christophe Sauboin, Lindner, Leandro, Vieta, A, Ana Vieta, Lindner, L, Sauboin, C, Sauboin, Christophe, Leandro Lindner   +14 more
core   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Malaria gestacional, congénita y placentaria de Urabá Antioquia, 2005-2007

, 2008
IP 1115-04-17041Contrato 316-2004Sinopsis divulgativa: El paludismo malaria es una infección que puede llegar a enfermar, a veces gravemente, a la mujer embarazada (gestante) que habita o que visita las zonas donde el paludismo en usual (endémico).

core   +1 more source

Pharmacometric evaluation of pre‐referral rectal artesunate in children with severe malaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Parenteral artesunate is the preferred first‐line treatment for severe malaria. Pre‐referral rectal artesunate suppositories are recommended where parenteral treatment is inaccessible. In this study, we compared dihydroartemisinin exposure and model‐predicted early parasite clearance following rectal artesunate and intravenous artesunate in ...
Ayorinde Adehin, Marie A. Onyamboko, Caterina Fanello, Nicholas J. White, Nicholas P. J. Day, Richard M. Hoglund, Joel Tarning   +6 more
wiley   +1 more source

Health worker and policy-maker perspectives on use of intramuscular artesunate for pre-referral and definitive treatment of severe malaria at health posts in Ethiopia

Malaria Journal, 2016
Background The World Health Organization (WHO) recommends injectable artesunate given either intravenously or by the intramuscular route for definitive treatment for severe malaria and recommends a single intramuscular dose of intramuscular artesunate or
Takele Kefyalew, Zelalem Kebede, Dawit Getachew, David Mukanga, Tessema Awano, Agonafer Tekalegne, Esey Batisso, Wasihun Edossa, Emebet Mekonnen, James Tibenderana, Ebenezer Sheshi Baba, Constance Shumba, Joaniter I. Nankabirwa, Prudence Hamade   +13 more
doaj   +1 more source

Capacity building in medicines development and regulation in Africa—Overview on recent progress

British Journal of Clinical Pharmacology, EarlyView.
Aims Despite advances in health research and digital innovation, many African countries continue to face substantial resource constraints, fragmented capacity‐building efforts and a shortage of skilled professionals in medicines development and regulatory science.
Tirhani Maluleke, Emile Malan, Michael Reid, Patrick Bouic, Haylene Nell, Goonaseelan Pillai, Catriona Waitt, Bernd Rosenkranz   +7 more
wiley   +1 more source

Childhood pneumonia diagnostics: community health workers’ and national stakeholders’ differing perspectives of new and existing aids

Global Health Action, 2017
Background: Pneumonia heavily contributes to global under-five mortality. Many countries use community case management to detect and treat childhood pneumonia. Community health workers (CHWs) have limited tools to help them assess signs of pneumonia. New
Hollie Spence, Kevin Baker, Alexandra Wharton-Smith, Akasiima Mucunguzi, Lena Matata, Tedila Habte, Diana Nanyumba, Anteneh Sebsibe, Thol Thany, Karin Källander   +9 more
doaj   +1 more source

Integrated community case management in a peri-urban setting: a qualitative evaluation in Wakiso District, Uganda

BMC Health Services Research, 2017
Background Integrated community case management (iCCM) strategies aim to reach poor communities by providing timely access to treatment for malaria, pneumonia and diarrhoea for children under 5 years of age.
Robin Altaras, Mark Montague, Kirstie Graham, Clare E. Strachan, Laura Senyonjo, Rebecca King, Helen Counihan, Denis Mubiru, Karin Källander, Sylvia Meek, James Tibenderana   +10 more
doaj   +1 more source

Determinants of malaria testing at health facilities: the case of Uganda

Malaria Journal, 2021
Background The World Health Organization (WHO) recommends prompt malaria diagnosis with either microscopy or malaria rapid diagnostic tests (RDTs) and treatment with an effective anti-malarial, as key interventions to control malaria.
Ruth N. Kigozi, JohnBaptist Bwanika, Emily Goodwin, Peter Thomas, Patrick Bukoma, Persis Nabyonga, Fred Isabirye, Paul Oboth, Carol Kyozira, Mame Niang, Kassahun Belay, Gloria Sebikaari, James K. Tibenderana, Sam Siduda Gudoi   +13 more
doaj   +1 more source