Results 41 to 50 of about 361,983 (304)

High‐Density E. Coli Cultivation Arrays for Combinatorial Drug Testing With Subsequent Lipid Profiling by MALDI‐MS

Advanced Science, EarlyView.
High‐throughput antibiotic cross‐gradient assays on microdroplet arrays. A multichannel printhead together with five pressure regulators forms droplet arrays of up to 20 832 droplets within 25 minutes. Each droplet contains unique concentrations of antibiotics, allowing to moniture a vast spectrum of bacterial repsonses over night. The bacterial growth
M. Breitfeld, C. L. Dietsche, F‐L. Born, I. Onipko, L. Blaase, P. S. Dittrich   +5 more
wiley   +1 more source

Delivering insecticide-treated nets (ITNs) through a digitized single-phase door-to-door strategy: lessons from Ondo state, Nigeria

Malaria Journal
Background The use of insecticide-treated nets (ITNs) is a strategy recommended by the World Health Organization (WHO) for malaria prevention. In Nigeria, ITNs have been periodically distributed since 2007 through campaigns.
Laitan Adeniyi, Elisabeth G. Chestnutt, Kunle Rotimi, Azuka Iwegbu, Olusola Oresanya, Julianna Smith, Kolawole Maxwell, Tarekegn A. Abeku   +7 more
doaj   +1 more source

Malaria [PDF]

Nature Reviews Disease Primers, 2017
(Uploaded by Plazi for the Bat Literature Project) Malaria is caused in humans by five species of single-celled eukaryotic Plasmodium parasites (mainly Plasmodium falciparum and Plasmodium vivax) that are transmitted by the bite of Anopheles spp. mosquitoes.
Margaret A, Phillips, Jeremy N, Burrows, Christine, Manyando, Rob Hooft, van Huijsduijnen, Wesley C, Van Voorhis, Timothy N C, Wells   +5 more
openaire   +3 more sources

Loop-mediated isothermal amplification (LAMP) for point-of-care detection of asymptomatic low-density malaria parasite carriers in Zanzibar. [PDF]

, 2015
BACKGROUND: Asymptomatic, low parasite density malaria infections are difficult to detect with currently available point-of-care diagnostics. This study piloted a loop-mediated isothermal amplification (LAMP) kit for field-friendly, high-throughput ...
Msellem, Mwinyi, Abass, Ali K, Mårtensson, Andreas, Schmidt, Berit, Abass, Ali K., Berit Aydin-Schmidt, Mwinyi Msellem, Nassor, Majda H, Cook, Jackie, Aydin-Schmidt, Berit, Nassor, Majda H., Björkman, Anders, Abdullah Ali, Elin Edlund, David Bell, Majda H Nassor, Andreas Mårtensson, Jackie Cook, Ali, Abdullah, Mårtensson, Andreas,, Anders Björkman, Gonzalez, Iveth J., González, Iveth J, Bell, David, Edlund, Elin, Ali K Abass, Iveth J González   +26 more
core   +1 more source

Artificial Intelligence‐Driven Network Pharmacology: A Methodological Paradigm Shift Bridging Traditional Wisdom and Modern Science

Advanced Intelligent Discovery, EarlyView.
Artificial intelligence is redefining network pharmacology (NP). By integrating knowledge graph engineering, geometric deep learning, multiomics anchoring, and generative reasoning, AI‐driven NP (AI‐NP) transforms static target mapping into dynamic, predictive modeling.
Cong Wang, Sile Hu, Rigahai Ji, Riguna A, Siqige Hao, Ma Zhuo, Yi‐Hung Chen, Bisihalatu Hu, Ulana Bai, Xigui Hada   +9 more
wiley   +1 more source

The acceptability of mass administrations of anti-malarial drugs as part of targeted malaria elimination in villages along the Thai–Myanmar border

Malaria Journal, 2016
Background A targeted malaria elimination project, including mass drug administrations (MDA) of dihydroartemisinin/piperaquine plus a single low dose primaquine is underway in villages along the Thailand Myanmar border.
Ladda Kajeechiwa, May Myo Thwin, Paw Wah Shee, Nan Lin Yee, Elvina Elvina, Peapah Peapah, Kyawt Kyawt, Poe Thit Oo, William PoWah, Jacqueline Roger Min, Jacher Wiladphaingern, Lorenz von Seidlein, Suphak Nosten, Francois Nosten   +13 more
doaj   +1 more source

Autoantibodies to Extracellular Erythrocyte Band 3 Epitopes Are Associated With Anemia in Plasmodium vivax Infection

American Journal of Hematology, EarlyView.
ABSTRACT Plasmodium vivax‐associated anemia is a multifactorial clinical outcome, in which the destruction of uninfected red blood cells (uRBCs) plays a major role in disease development and severity. Here, we identified autoantibody targets within the extracellular loops of Band 3 (B3), a major erythrocyte transmembrane protein.
Aline Marzano‐Miranda, Vanessa G. Fraga, Cor Jésus F. Fontes, Simone Ladeia‐Andrade, Marcelo U. Ferreira, Daniella C. Bartholomeu, Érika M. Braga   +6 more
wiley   +1 more source

Delivering an insecticide-treated net campaign in a complex operating environment: lessons from Anambra state, Nigeria

Malaria Journal
Background Malaria is one of the leading causes of morbidity and mortality in Nigeria. Distribution of insecticide-treated nets (ITNs) is an important vector control strategy.
Laitan Adeniyi, Kunle Rotimi, Elisabeth G. Chestnutt, Abiola O. Oluwagbemiga, Saliu Ogunmola, Nonso Ndibe, Olusola Oresanya, Julianna Smith, Kolawole Maxwell, Tarekegn A. Abeku   +9 more
doaj   +1 more source

Multi-country review of ITN routine distribution data: are ANC and EPI channels achieving their potential?

Malaria Journal, 2022
Background Routine continuous distribution (CD) of insecticide-treated nets (ITNs) has been an important part of an overall ITN strategy to complement mass campaigns since the early 2000s.
Jane E. Miller, Kezia Malm, Aimain Alexis Serge, Marcellin Joel Ateba, Peter Gitanya, Doudou Sene, Emmanuel H. Kooma, Balla Kandeh, Lilia Gerberg, Luigi Nuñez   +9 more
doaj   +1 more source

Rapid Urban Malaria Appraisal (RUMA) II: epidemiology of urban malaria in Dar es Salaam (Tanzania). [PDF]

, 2006
BACKGROUND\ud \ud The thinking behind malaria research and control strategies stems largely from experience gained in rural areas and needs to be adapted to the urban environment.\ud \ud METHODS\ud \ud A rapid assessment of urban malaria was conducted in
Godson Maro, Wang Shr-Jie, Marcel Tanner, S., Lusinge Manane, Manane, Lusinge, Christian Lengeler, Shr-Jie Wang, Mtasiwa, Deodatus, Deodatus Mtasiwa, Penelope Vounatsou, Marcel Tanner, Lengeler Christian, Vounatsou Penelope, Guéladio Cissé, Maro, G., Wang, S.-J., Lengeler, C., Tanner, Marcel, Lengeler, Christian, Mtasiwa, D., Cissé Guéladio, Mshana, Thomas, Mshana Thomas, Mshana, T., Tanner Marcel, Manane, L., Mtasiwa Deodatus, Maro Godson, Thomas Mshana, Smith Thomas A, Wang, Shr-Jie, Manane Lusinge, Thomas A Smith, Maro, Godson   +33 more
core   +1 more source