Results 31 to 40 of about 231,969 (238)

Delivering an insecticide-treated net campaign in a complex operating environment: lessons from Anambra state, Nigeria

Malaria Journal
Background Malaria is one of the leading causes of morbidity and mortality in Nigeria. Distribution of insecticide-treated nets (ITNs) is an important vector control strategy.
Laitan Adeniyi, Kunle Rotimi, Elisabeth G. Chestnutt, Abiola O. Oluwagbemiga, Saliu Ogunmola, Nonso Ndibe, Olusola Oresanya, Julianna Smith, Kolawole Maxwell, Tarekegn A. Abeku   +9 more
doaj   +1 more source

Multi-country review of ITN routine distribution data: are ANC and EPI channels achieving their potential?

Malaria Journal, 2022
Background Routine continuous distribution (CD) of insecticide-treated nets (ITNs) has been an important part of an overall ITN strategy to complement mass campaigns since the early 2000s.
Jane E. Miller, Kezia Malm, Aimain Alexis Serge, Marcellin Joel Ateba, Peter Gitanya, Doudou Sene, Emmanuel H. Kooma, Balla Kandeh, Lilia Gerberg, Luigi Nuñez   +9 more
doaj   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

A quasi-experimental study to estimate effectiveness of seasonal malaria chemoprevention in Aweil South County in Northern Bahr El Ghazal, South Sudan

Malaria Journal
Background Seasonal malaria chemoprevention (SMC) is an effective intervention to prevent malaria in children in locations where the burden of malaria is high and transmission is seasonal.
Jamshed Khan, Maria Suau Sans, Francis Okot, Abubaker Rom Ayuiel, Jonathan Magoola, Christian Rassi, Sikai Huang, Denis Mubiru, Craig Bonnington, Kevin Baker, Julla Ahmed, Chuks Nnaji, Sol Richardson   +12 more
doaj   +1 more source

One-arm safety intervention study on community case management of chest indrawing pneumonia in children in Nigeria – a study protocol

Global Health Action, 2020
Current recommendations within integrated community case management (iCCM) programmes advise community health workers (CHWs) to refer cases of chest indrawing pneumonia to health facilities for treatment, but many children die due to delays or non ...
Helen Counihan, Ebenezer Baba, Olusola Oresanya, Olatunde Adesoro, Yahya Hamzat, Sarah Marks, Charlotte Ward, Patrick Gimba, Shamim Ahmad Qazi, Karin Källander   +9 more
doaj   +1 more source

“More” Artificial mRNAs: Beyond the Art of Nature

Advanced Science, EarlyView.
Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Yuanzhe Cui, Minami Fukui, Hirohisa Ohno, Hirohide Saito   +3 more
wiley   +1 more source

Health worker and policy-maker perspectives on use of intramuscular artesunate for pre-referral and definitive treatment of severe malaria at health posts in Ethiopia

Malaria Journal, 2016
Background The World Health Organization (WHO) recommends injectable artesunate given either intravenously or by the intramuscular route for definitive treatment for severe malaria and recommends a single intramuscular dose of intramuscular artesunate or
Takele Kefyalew, Zelalem Kebede, Dawit Getachew, David Mukanga, Tessema Awano, Agonafer Tekalegne, Esey Batisso, Wasihun Edossa, Emebet Mekonnen, James Tibenderana, Ebenezer Sheshi Baba, Constance Shumba, Joaniter I. Nankabirwa, Prudence Hamade   +13 more
doaj   +1 more source

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

Advanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang, Hongyi Zhang, Haixiang Guo, Xiwen Zhang, Yidan Wang, Baoyin Wang, Tong Wang, Guokun Zhao, Qing Zhang, Fei Gao, Shuang Liang, Hao Jiang, Yu Ding, Xiliang Du, Jiabao Zhang, Yi Zheng, Xinwei Li, Bao Yuan   +17 more
wiley   +1 more source

Determinants of malaria testing at health facilities: the case of Uganda

Malaria Journal, 2021
Background The World Health Organization (WHO) recommends prompt malaria diagnosis with either microscopy or malaria rapid diagnostic tests (RDTs) and treatment with an effective anti-malarial, as key interventions to control malaria.
Ruth N. Kigozi, JohnBaptist Bwanika, Emily Goodwin, Peter Thomas, Patrick Bukoma, Persis Nabyonga, Fred Isabirye, Paul Oboth, Carol Kyozira, Mame Niang, Kassahun Belay, Gloria Sebikaari, James K. Tibenderana, Sam Siduda Gudoi   +13 more
doaj   +1 more source

Malaria [PDF]

Nature Reviews Disease Primers, 2017
(Uploaded by Plazi for the Bat Literature Project) Malaria is caused in humans by five species of single-celled eukaryotic Plasmodium parasites (mainly Plasmodium falciparum and Plasmodium vivax) that are transmitted by the bite of Anopheles spp. mosquitoes.
Margaret A, Phillips, Jeremy N, Burrows, Christine, Manyando, Rob Hooft, van Huijsduijnen, Wesley C, Van Voorhis, Timothy N C, Wells   +5 more
openaire   +2 more sources