Results 61 to 70 of about 747,084 (353)

Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia [PDF]

, 2017
Hydroxyurea treatment is recommended for children with sickle cell anemia (SCA) living in high-resource malaria-free regions, but its safety and efficacy in malaria-endemic sub-Saharan Africa, where the greatest sickle-cell burden exists, remain unknown.
Hodges, James S., Hume, Heather A., John, Chandy C., Kasirye, Phillip, Lane, Adam, Latham, Teresa S., Ndugwa, Christopher M., Opoka, Robert O., Ware, Russell E.   +8 more
core   +2 more sources

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

HUBUNGAN PERILAKU MASYARAKAT DENGAN KEJADIAN MALARIA DESA KORE KECAMATAN SANGGAR KABUPATEN BIMA [PDF]

, 2005
Malaria adalah penyakit infeksi yang masih menjadi masalah kesehatan masyarakat. Desa Kore merupakan daerah endemis. Pada tahun 2004 terjdi KLB malaria dengan jumlah penderita malaria klinis 1.282 (AMI=264,38 0/00).
FARIED , MOCH. FARIED
core  

People's perception of malaria in Mbarara, Uganda.

, 2002
To understand people's perceptions of malaria and their implications for control programmes, we held focus group discussions (FGDs) and conducted semi-structured interviews (SSIs) with community members in Mbarara, Uganda.
Nuwaha, Fred
core   +1 more source

Intermittent preventive treatment of malaria provides substantial protection against malaria in children already protected by an insecticide-treated bednet in Burkina Faso: a randomised, double-blind, placebo-controlled trial. [PDF]

, 2011
BACKGROUND: Intermittent preventive treatment of malaria in children (IPTc) is a promising new approach to the control of malaria in areas of seasonal malaria transmission but it is not known if IPTc adds to the protection provided by an insecticide ...
Chandramohan, Daniel, Cousens, Simon, Diallo, Diadier A, Diarra, Amidou, Gansané, Adama, Greenwood, Brian, Kaboré, Youssouf, Kangoyé, David T, Konaté, Amadou T, Milligan, Paul J, Ouédraogo, Alphonse, Ouédraogo, Amidou Z, Ouédraogo, Espérance, Ouédraogo, Issa N, Sirima, Sodiomon B, Soulama, Issiaka, Tiono, Alfred B, Yaro, Jean Baptiste   +17 more
core   +3 more sources

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

Advanced Science, EarlyView.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li, Ya‐Li Zhang, Tong Jin, Zhaokui Jin, Mengliang Zhu, Guangchao Qing, Jinchao Zhang, Zhisen Wang, Yan Mu, Jin Li, Qian Hua, Xing‐Jie Liang   +11 more
wiley   +1 more source

Childhood pneumonia diagnostics: community health workers’ and national stakeholders’ differing perspectives of new and existing aids

Global Health Action, 2017
Background: Pneumonia heavily contributes to global under-five mortality. Many countries use community case management to detect and treat childhood pneumonia. Community health workers (CHWs) have limited tools to help them assess signs of pneumonia. New
Hollie Spence, Kevin Baker, Alexandra Wharton-Smith, Akasiima Mucunguzi, Lena Matata, Tedila Habte, Diana Nanyumba, Anteneh Sebsibe, Thol Thany, Karin Källander   +9 more
doaj   +1 more source

Insecticide resistance patterns in Uganda and the effect of indoor residual spraying with bendiocarb on kdr L1014S frequencies in Anopheles gambiae s.s.

Malaria Journal, 2017
Background Resistance of malaria vectors to pyrethroid insecticides has been attributed to selection pressure from long-lasting insecticidal nets (LLINs), indoor residual spraying (IRS), and the use of chemicals in agriculture.
Tarekegn A. Abeku, Michelle E. H. Helinski, Matthew J. Kirby, James Ssekitooleko, Chris Bass, Irene Kyomuhangi, Michael Okia, Godfrey Magumba, Sylvia R. Meek   +8 more
doaj   +1 more source

Malaria Diagnosis and the Plasmodium Life Cycle: the BFO Perspective [PDF]

, 2009
Definitive diagnosis of malaria requires the demonstration through laboratory tests of the presence within the patient of malaria parasites or their components.
Barry Smith, Werner Ceusters
core   +3 more sources

Novel Cyano‐Artemisinin Dimer ZQJ29 Targets PARP1 to Induce Ferroptosis in Pancreatic Cancer Treatment

Advanced Science, EarlyView.
A novel artemisinin derivative dimer has been synthesized, and its significant potential as an anti‐cancer agent. The study indicated that ZQJ29 effectively inhibited the proliferation of pancreatic cancer cells in vitro and in vivo. Additionally, these investigations have unveiled ZQJ29 as a new potent PARP1 inhibitor, with the capability to induce ...
Jianping Chen, Lingyun Yue, Yanna Pan, Bingying Jiang, Junfeng Wan, Haixia Lin, Fujiang Guo, Huiyu Li, Yajuan Li, Qingjie Zhao   +9 more
wiley   +1 more source