Results 41 to 50 of about 97,814 (302)

En-route to the ‘elimination’ of genotypic chloroquine resistance in Western and Southern Zambia, 14 years after chloroquine withdrawal

Malaria Journal, 2019
Background Anti-malarial resistance is, and continues to be a significant challenge in the fight against malaria and a threat to achieving malaria elimination.
Lungowe Sitali, Mulenga C. Mwenda, John M. Miller, Daniel J. Bridges, Moonga B. Hawela, Elizabeth Chizema-Kawesha, James Chipeta, Bernt Lindtjørn   +7 more
doaj   +1 more source

The Stability of Malaria Elimination

Science, 2013
Eradication may not be necessary before countries can eliminate, scale back control, and rely on health systems.
Chiyaka, C, Tatem, A, Cohen, J, Gething, P, Johnston, G, Gosling, R, Laxminarayan, R, Hay, S, Smith, D   +8 more
openaire   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Malaria elimination and the need for intensive inter-country cooperation: a critical evaluation of regional technical co-operation in Southern Africa

Malaria Journal
Background Malaria elimination requires closely co-ordinated action between neighbouring countries. In Southern Africa several countries have reduced malaria to low levels, but the goal of elimination has eluded them thus far.
Chadwick H. Sikaala, Bongani Dlamini, Alphart Lungu, Phelele Fakudze, Mukosha Chisenga, Chishala Lukwesa Siame, Nyasha Mwendera, Dumisani Shaba, John M. Chimumbwa, Immo Kleinschmidt   +9 more
doaj   +1 more source

The long road to elimination: malaria mortality in a South African population cohort over 21 years. [PDF]

, 2017
BACKGROUND: Malaria elimination is on global agendas following successful transmission reductions. Nevertheless moving from low to zero transmission is challenging.
Byass, P, Coetzee, M, Collinson, MA, Gómez-Olivé, FX, Kabudula, C, Kahn, K, Mee, P, Ngobeni, S, Silaule, B, Tollman, SM, Twine, W, Wagner, RG   +11 more
core   +2 more sources

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Quality of inpatient test-and-treat malaria case-management in public and private hospitals in Kano State, Nigeria

Malaria Journal
Background Compliance with evidence-based treatment guidelines, supported by quality-assured parasitological diagnosis, is the mainstay of malaria case-management in Nigeria.
Dawit Getachew, Nnenna Ogbulafor, Emmanuel Shekarau, Babangida Musa, Abdullahi Yusuf, Safiyanu Haruna, Oladipo O. Oladosu, Olusola Oresanya, Kolawole Maxwell, Dejan Zurovac   +9 more
doaj   +1 more source

History of malaria control in Rwanda: implications for future elimination in Rwanda and other malaria-endemic countries

Malaria Journal, 2020
Background Malaria was first reported in Rwanda in the early 1900s with significant heterogeneity and volatility in transmission over subsequent decades.
Corine Karema, Shawn Wen, Abigail Sidibe, Jennifer L. Smith, Roly Gosling, Emmanuel Hakizimana, Marcel Tanner, Abdisalan M. Noor, Allison Tatarsky   +8 more
doaj   +1 more source

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

Advanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang, Hongyi Zhang, Haixiang Guo, Xiwen Zhang, Yidan Wang, Baoyin Wang, Tong Wang, Guokun Zhao, Qing Zhang, Fei Gao, Shuang Liang, Hao Jiang, Yu Ding, Xiliang Du, Jiabao Zhang, Yi Zheng, Xinwei Li, Bao Yuan   +17 more
wiley   +1 more source

Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases

Advanced Science, EarlyView.
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao, Victor Fernandez‐Gonzalez, Xiaochuan Wang, Blake Pylipow, Claudia Herrera, Xiaohu Xia   +5 more
wiley   +1 more source