Results 81 to 90 of about 44,517 (310)

Malaria parasite density and detailed qualitative microscopy enhances large-scale profiling of infection endemicity in Nigeria

Scientific Reports, 2023
With global progress towards malaria reduction stalling, further analysis of epidemiology is required, particularly in countries with the highest burden.
Wellington Oyibo, Victoria Latham, Oladosu Oladipo, Godwin Ntadom, Perpetua Uhomoibhi, Nnenna Ogbulafor, Chukwu Okoronkwo, Festus Okoh, Aminu Mahmoud, Emmanuel Shekarau, Olusola Oresanya, Yakubu Joel Cherima, Innua Jalingo, Bintu Abba, Mohammed Audu, David J. Conway   +15 more
doaj   +1 more source

Repurposing Drugs for Malaria through a Human Dose Prediction: A Case Study with Berzosertib

Clinical Pharmacology &Therapeutics, EarlyView.
Repurposing drugs whose clinical safety has been established offers a valuable approach to reduce the cost and time associated with the development of new drugs for malaria. Here, we investigate the potential to repurpose the anticancer kinase inhibitor berzosertib for the treatment of malaria, by assessing whether a predicted efficacious human dose ...
Devasha Redhi, Mwila Mulubwa, Mmakwena M. Mmonwa, Mathew Njoroge, Liezl Krugmann, Kelly Chibale   +5 more
wiley   +1 more source

Estimating the size of populations at risk for malaria: a case study in cattle herders and agricultural workers in Northern Namibia

Scientific Reports
Cattle herders and agricultural workers have been identified has key high-risk populations for malaria in northern Namibia. Population size estimates for these groups are lacking but are important for planning, monitoring and evaluating the effectiveness
Francois Rerolle, Jerry O. Jacobson, Cara Smith Gueye, Adam Bennett, Sidney Carrillo, Henry Ntuku, Jennifer L. Smith   +6 more
doaj   +1 more source

Predicting the cost-effectiveness of strategies for case management of "plasmodium falciparum" malaria in Sub-Saharan Africa [PDF]

, 2013
Malaria is an important cause of death and illness in children and adults, particularly in the tropics. The World Health Organization (WHO) estimated that, worldwide, there were 655,000 malaria deaths in 2010, of which 91% were in Africa, and 216 million
Crowell, Valerie
core   +1 more source

What Do We Know About How Companies Manage Waste? The Effect of Tenure and Diversity of Directors on Disclosures

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This paper aims to analyze the effect of board tenure on firms' waste management disclosure and explore whether this effect is amplified by board gender and cultural diversity. The analysis is based on data from 832 large firms worldwide from 2011 to 2020.
Isabel‐María García‐Sánchez, Beatriz Aibar‐Guzmán, Salvador Marín‐Hernández, Esther Ortiz‐Martínez   +3 more
wiley   +1 more source

Target product profiles for protecting against outdoor malaria transmission. [PDF]

, 2012
BACKGROUND\ud \ud Long-lasting insecticidal nets (LLINs) and indoor residual sprays (IRS) have decimated malaria transmission by killing indoor-feeding mosquitoes.
Killeen, Gerry, Moore, Sarah J, Killeen, Gerry F, Moore Sarah J, Gerry F Killeen, Sarah J Moore, Killeen Gerry F   +6 more
core   +1 more source

Enantiospecific Acid‐Catalysed Hydroperoxidation of Scalemic Tertiary Benzylic Alcohols Facilitating a Concise Asymmetric Synthesis of Yingzhaosu C

European Journal of Organic Chemistry, EarlyView.
Asymmetric synthesis of antimalarial yingzhaosu C was achieved in 4–5 steps by asymmetric Grignard synthesis of (R)‐gossonorol followed by novel enantiospecific hydroperoxidation. We report a concise asymmetric synthesis of antimalarial yingzhaosu C in 59% ee.
Saranna E. Kavanagh, Claudio Monasterolo, Declan G. Gilheany   +2 more
wiley   +1 more source

Prevalence of K13 mutation and Day-3 positive parasitaemia in artemisinin-resistant malaria endemic area of Cambodia: a cross-sectional study

Malaria Journal, 2017
Background The presence of artemisinin-resistant malaria parasites was confirmed in western Cambodia in 2009. In 2013, mutations in the propeller domain of the kelch protein K13 was found to be associated with artemisinin resistance.
Soy Ty Kheang, Siv Sovannaroth, Sovann Ek, Say Chy, Phally Chhun, Sokkieng Mao, Sokomar Nguon, Dy Soley Lek, Didier Menard, Neeraj Kak   +9 more
doaj   +1 more source

The Evolution of the Malaria Clinic: The Cornerstone of Malaria Elimination in Thailand [PDF]

Tropical Medicine and Infectious Disease, 2019
Background: Malaria Clinics (MCs) have served communities in Thailand since 1965 and are still playing a critical role in providing early diagnosis and effective treatment of malaria. Methods: We reviewed six decades of published manuscripts, articles, strategies, and plans regarding MC operations in Thailand;,and analyzed national program surveillance
Prayuth Sudathip, Suravadee Kitchakarn, Krongthong Thimasarn, Deyer Gopinath, Tinzar Naing, Omar Sajjad, Sumetha Hengprasert   +6 more
openaire   +2 more sources

Can economic analysis contribute to disease elimination and eradication? : A systematic review [PDF]

, 2015
BACKGROUND: Infectious diseases elimination and eradication have become important areas of focus for global health and countries. Due to the substantial up-front investments required to eliminate and eradicate, and the overall shortage of resources for ...
Sicuri, E, Evans, David B., Tediosi, F., Elisa Sicuri, Sicuri, Elisa, Tediosi, F, Fabrizio Tediosi (247282), Evans, David B, Evans David B., David B Evans, Sicuri Elisa, Sicuri, E., David B. Evans (569557), Evans, DB, Tediosi Fabrizio, Tediosi, Fabrizio, Evans, D. B., Fabrizio Tediosi, Elisa Sicuri (247271)   +18 more
core   +1 more source