Results 11 to 20 of about 106,967 (273)

Malaria vaccines [PDF]

Medical Journal of Australia, 2002
Malaria kills one child in Africa every 30 s. After summarising the burden of malaria, the life-cycle of this parasite in humans and female Anopheles mosquitoes is outlined. Important differences between natural immunity and that induced by current candidate vaccines are discussed.
Graham V, Brown, John C, Reeder
openaire   +5 more sources

RETRACTION: Top 100 cited articles on anosmia and COVID‐19: a bibliometric analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView., 2023
Retraction: Tan, DJY, Ko, TK. Top 100 cited articles on anosmia and COVID‐19: a bibliometric analysis. World J Otorhinolaryngol Head Neck Surg. 2023; 1–8. doi:10.1002/wjo2.125. The above article, published online on 28 July 2023 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal's Editor ...
Denise Jia Yun Tan, Tsz Ki Ko
wiley   +1 more source

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero, Jorge Serrano, Nicole Birgit Arweiler, Thorsten Mathias Auschill, Ali Gürkan, Gülnur Emingil   +5 more
wiley   +1 more source

Malaria vaccines [PDF]

Proceedings of the National Academy of Sciences, 1999
Malaria remains one of the most important vector-borne human diseases. Control of malaria caused by Plasmodium falciparum is a major goal, particularly for populations in sub-Saharan Africa. An effective vaccine against malaria that would protect nonimmune individuals from the disease has long been a dream. But will it be a reality?
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Vaccines Against Malaria [PDF]

Clinical Infectious Diseases, 2014
Despite global efforts to control malaria, the illness remains a significant public health threat. Currently, there is no licensed vaccine against malaria, but an efficacious vaccine would represent an important public health tool for successful malaria elimination.
Amed, Ouattara, Matthew B, Laurens
openaire   +2 more sources

Natural immunity to malaria preferentially targets the endothelial protein C receptor-binding regions of PfEMP1s

mSphere, 2023
Antibody responses to variant surface antigens (VSAs) produced by the malaria parasite Plasmodium falciparum may contribute to age-related natural immunity to severe malaria. One VSA family, P. falciparum erythrocyte membrane protein-1 (PfEMP1), includes
Madison A. Tewey, Drissa Coulibaly, Jonathan G. Lawton, Emily M. Stucke, Albert E. Zhou, Andrea A. Berry, Jason A. Bailey, Andrew Pike, Antoine Dara, Amed Ouattara, Kirsten E. Lyke, Olukemi Ifeonu, Matthew B. Laurens, Matthew Adams, Shannon Takala-Harrison, Amadou Niangaly, Bourema Kouriba, Abdoulaye K. Koné, J. Alexandra Rowe, Ogobara K. Doumbo, Jigar J. Patel, John C. Tan, Philip L. Felgner, Christopher V. Plowe, Mahamadou A. Thera, Mark A. Travassos   +25 more
doaj   +1 more source

Satisfactory safety and immunogenicity of MSP3 malaria vaccine candidate in Tanzanian children aged 12-24 months. [PDF]

, 2009
BACKGROUND: Development and deployment of an effective malaria vaccine would complement existing malaria control measures. A blood stage malaria vaccine candidate, Merozoite Surface Protein-3 (MSP3), produced as a long synthetic peptide, has been shown ...
Bosomprah, Samuel, Chilengi, Roma, Cousens, Simon, Druilhe, Pierre, Francis, Filbert, Gesase, Samwel, Lemnge, Martha, Lusingu, John PA, Minja, Daniel, Msham, Salum, Noor, Ramadhani, Rutta, Acleus, Segeja, Method D, Sembuche, Samwel, Seth, Misago   +14 more
core   +2 more sources

Novel malaria vaccines [PDF]

Human Vaccines & Immunotherapeutics, 2021
Malaria vaccines hold significant promise for life-saving benefit, especially to children who bear the major burden of malaria mortality. The RTS,S/AS01 malaria vaccine provides moderate efficacy and is being tested in implementation studies. In parallel, multiple strategies are being advanced to test next-generation malaria vaccines, including novel ...
openaire   +3 more sources

Novel sporozoite-based ELISpot assay to assess frequency of parasite-specific B cells after vaccination with irradiated sporozoites

Malaria Journal, 2019
Background Whole parasite vaccination is an efficacious strategy to induce sterile immunity and to prevent malaria transmission. Understanding the mechanism and response of immune cells to vaccines plays a critical role in deciphering correlates of ...
Tanmaya Atre, Tanisha M. Robinson, Tatyana Savransky, Sheetij Dutta, Judith E. Epstein, Elke S. Bergmann-Leitner   +5 more
doaj   +1 more source

Experience and Challenges from Clinical Trials with Malaria Vaccines in Africa. [PDF]

, 2013
Malaria vaccines are considered amongst the most important modalities for potential elimination of malaria disease and transmission. Research and development in this field has been an area of intense effort by many groups over the last few decades ...
A Nyika, A Olotu, A Roca-Feltrer, AA Holder, AJ Luty, AVS Hill, B Moonen, Bernhards Ogutu, Beverly Msambichaka, BF Chumpitazi, Bouharoun-Tayoun H Druilhe P, C Guinovart, C Roussilhon, C Swysen, DA Chokshi, DA Diallo, E Peduzzi, Eakin, Bull SS, Riley K,Reeves MM, Gutierrez S, McLaughlin P, FM Ndungu, FM Ndungu, FM Thompson, Grace Mwangoka, H Bouharoun-Tayoun, HL Smits, I Nebie, J Schantz-Dunn, JL Sarthou, K Miura, K Shubis, KE Kester, KE Kester, KP Asante, L Schwartz, M Roestenberg, M Roestenberg, Marcel Tanner, Maxmillian Mpina, MP Girad, Nahya Salim, NC Iriemenam, NJ White, OK Doumbo, PG Cech, PL Alonso, PL Alonso, PL Alonso, PO Tindana, R Chilengi, RR Taylor, S Casares, Salim Abdulla, Seif Shekalaghe, Shubis Kafuruki, SJ Rogerson, SL Hoffman, ST Agnandji, ST Agnandji, T Smith, T Smith, T Smith, TA Lang, The malERA Consultative Group on Vaccines, Tutu Mzee, V Gardette, V Moorthy, WHO, WHO, YP Shi   +67 more
core   +3 more sources