Results 51 to 60 of about 106,967 (273)

Peptide data on the disulfide bond analysis of baculovirus produced Pfs25 by LC-MSMS

Data in Brief, 2018
This article contains the peptide data obtained while performing disulfide bond mapping of the recombinant Plasmodium falciparum protein, Pfs25, produced from the baculovirus expression system.
Shwu-Maan Lee, Jordan L. Plieskatt, C. Richter King   +2 more
doaj   +1 more source

Plasmodium falciparum infection and disease in infancy associated with increased risk of malaria and anaemia in childhood

Malaria Journal, 2023
Background Infants under 6 months of age are often excluded from malaria surveillance and observational studies. The impact of malaria during early infancy on health later in childhood remains unknown.
Liana R. Andronescu, Andrea G. Buchwald, Ankur Sharma, Andy Bauleni, Patricia Mawindo, Yuanyuan Liang, Julie R. Gutman, Don P. Mathanga, Jobiba Chinkhumba, Miriam K. Laufer   +9 more
doaj   +1 more source

Monoclonal Antibodies against Plasmodium falciparum Circumsporozoite Protein

Antibodies, 2017
Malaria is a mosquito-borne infectious disease caused by the parasite Plasmodium spp. Malaria continues to have a devastating impact on human health. Sporozoites are the infective forms of the parasite inside mosquito salivary glands.
Min Zhang, Rajakumar Mandraju, Urvashi Rai, Takayuki Shiratsuchi, Moriya Tsuji   +4 more
doaj   +1 more source

Theoretical implications of a pre-erythrocytic Plasmodium vivax vaccine for preventing relapses [PDF]

, 2017
Preventing malaria infection through vaccination requires preventing every sporozoite inoculated by mosquito bite: a major challenge for Plasmodium falciparum.
Amino, R, Mueller, I, White, MT
core   +3 more sources

Analysis of erythrocyte dynamics in Rhesus macaque monkeys during infection with Plasmodium cynomolgi

Malaria Journal, 2018
Background Malaria is a major mosquito transmitted, blood-borne parasitic disease that afflicts humans. The disease causes anaemia and other clinical complications, which can lead to death.
Luis L. Fonseca, Chester J. Joyner, Celia L. Saney, The MaHPIC Consortium, Alberto Moreno, John W. Barnwell, Mary R. Galinski, Eberhard O. Voit   +7 more
doaj   +1 more source

Vaccines against malaria [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2011
There is no licenced vaccine against any human parasitic disease and Plasmodium falciparum malaria, a major cause of infectious mortality, presents a great challenge to vaccine developers. This has led to the assessment of a wide variety of approaches to malaria vaccine design and development, assisted by the ...
openaire   +3 more sources

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

Optimization of an in vivo model to study immunity to Plasmodium falciparum pre-erythrocytic stages

Malaria Journal, 2019
Background The circumsporozoite protein (CSP) of Plasmodium is a key surface antigen that induces antibodies and T-cells, conferring immune protection in animal models and humans.
Yevel Flores-Garcia, Sonia M. Herrera, Hugo Jhun, Daniel W. Pérez-Ramos, C. Richter King, Emily Locke, Ramadevi Raghunandan, Fidel Zavala   +7 more
doaj   +1 more source

Serologic responses to the PfEMP1 DBL-CIDR head structure may be a better indicator of malaria exposure than those to the DBL-α tag

Malaria Journal, 2019
Background Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1) antigens play a critical role in host immune evasion. Serologic responses to these antigens have been associated with protection from clinical malaria, suggesting that antibodies to
Emily M. Stucke, Amadou Niangaly, Andrea A. Berry, Jason A. Bailey, Drissa Coulibaly, Amed Ouattara, Kirsten E. Lyke, Matthew B. Laurens, Antoine Dara, Matthew Adams, Jozelyn Pablo, Algis Jasinskas, Rie Nakajima, Albert E. Zhou, Sonia Agrawal, DeAnna J. Friedman-Klabanoff, Shannon Takala-Harrison, Bourema Kouriba, Abdoulaye K. Kone, J. Alexandra Rowe, Ogobara K. Doumbo, Philip L. Felgner, Mahamadou A. Thera, Christopher V. Plowe, Mark A. Travassos   +24 more
doaj   +1 more source

RTS,S/AS02 and the quest of the Holy Grail [PDF]

, 2002
High-profile programs under the WHO/Roll Back Malaria initiative, in addition to unravelling the human and malaria parasite genomes, have ensured that malaria vaccine research and development are enjoying an unprecedented boom. So far, the development of
Reithinger, R
core