History of the discovery of the malaria parasites and their vectors [PDF]
Malaria is caused by infection with protozoan parasites belonging to the genus Plasmodium transmitted by female Anopheles species mosquitoes. Our understanding of the malaria parasites begins in 1880 with the discovery of the parasites in the blood of malaria patients by Alphonse Laveran.
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PEG400 regulates Falcipain 2 activity through an allosteric mechanism
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath +2 more
wiley +1 more source
Influence of health systems in malaria case management as part of malaria control in Tanzania [PDF]
The World Health Organization report in 2007, declared that, it will not be possible to achieve national and international health goals without greater investments in health systems.
Masanja, Irene M.
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Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes
C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli +6 more
wiley +1 more source
Towards malaria prediction in Sri Lanka. modelling spatial and temporal variability of malaria case counts [PDF]
This thesis was motivated by the need of the Anti Malaria Campaign (AMC) of Sri Lanka for malaria risk maps and malaria case number predictions to assist in the planning for malaria control.
Briët, Olivier J.T.
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Gender Justice in the Triple Planetary Crisis: A Scoping Review
ABSTRACT Aim To identify and report how gender justice is conceptualised and discussed in contemporary health literature in relation to the Triple Planetary Crisis of climate change, pollution and biodiversity loss, with a particular focus on the experiences of women and gender‐diverse populations, and the representation of nurses and other healthcare ...
Catelyn Richards +7 more
wiley +1 more source
Spatially aggregated clusters and scattered smaller loci of elevated malaria vector density and human infection prevalence in urban Dar es Salaam, Tanzania [PDF]
BACKGROUND: Malaria transmission, primarily mediated by Anopheles gambiae, persists in Dar es Salaam (DSM) despite high coverage with bed nets, mosquito-proofed housing and larviciding.
Mwakalinga, Victoria M. +20 more
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Characterization of Sec14 Domain–Containing Proteins in the Malaria Parasite Plasmodium falciparum
During asexual blood‐stage development, P. falciparum Sec14 proteins display distinct localizations suggesting specialized roles in lipid exchange. PfSec14‐1 initially localizes to the nucleus before moving to the ER and Golgi alongside PfSec14‐4 during schizogony.
Florian Lauruol +5 more
wiley +1 more source
Mosquito borne diseases in England:: past, present and future risks, with special reference to malaria in the Kent Marshes. [PDF]
Malaria was once common in the marshes of southern England. In this study I investigated why a disease called benign tertian malaria became known as the killer of the marshes and looked at the present and future threat from malaria returning to these ...
Hutchinson, Robert A.
core
Vector Biology and Integrated Management of Malaria Vectors in China
Malaria is an infectious disease caused by Plasmodium parasites, transmitted by Anopheles sinensis, Anopheles lesteri, Anopheles minimus, and Anopheles dirus in China. In 2021, the disease was eliminated in China after more than 70 years of efforts implementing an integrated mosquito management strategy.
Tongyan, Zhao, Rui-De, Xue
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