Results 71 to 80 of about 38,153 (221)
History of the discovery of the malaria parasites and their vectors [PDF]
Malaria is caused by infection with protozoan parasites belonging to the genus Plasmodium transmitted by female Anopheles species mosquitoes. Our understanding of the malaria parasites begins in 1880 with the discovery of the parasites in the blood of malaria patients by Alphonse Laveran.
openaire +4 more sources
Avian haemosporidian blood parasites are typically identified through Sanger sequencing of a partial cytochrome b fragment, the MalAvi barcoding region. Next‐generation sequencing is seldom used for avian blood parasite identification; this study demonstrates a higher detection rate of co‐infections via metabarcoding and its possible implications ...
Peter Pibaque +9 more
wiley +1 more source
Background Changes in land use and land cover (LULC) as well as climate are likely to affect the geographic distribution of malaria vectors and parasites in the coming decades.
Temitope O. Alimi +7 more
doaj +1 more source
Urbanization and Vector Species Shape Avian Malaria Prevalence in Mosquitoes
Avian malaria prevalence was assessed in two mosquito species across urban and peri‐urban habitats. No infections were detected in either species in urban areas, while a 2.53% prevalence was found in the native Culex pipiens from peri‐urban sites, highlighting the influence of urbanization on parasite transmission dynamics.
Paula Parra +5 more
wiley +1 more source
Background In the northeastern region of India, perennial malaria transmission persists in certain hotspots in areas geographically adjacent to the international borders with Bhutan, Bangladesh, and Myanmar, where both Plasmodium vivax and Plasmodium ...
Kuldeep Singh +8 more
doaj +1 more source
A Global Perspective of Childhood Vaccinations: Past, Present, and Future—From Smallpox to mRNA
ABSTRACT Childhood immunisation is one of the most successful public health interventions in history, preventing millions of deaths and substantially reducing global child mortality. This mini‐review summarises the historical development of childhood vaccines, the role of global coordination in expanding immunisation coverage, and the innovations that ...
Tobias Alfvén, Tania Reza, Alieu Sowe
wiley +1 more source
Despite its success, the increased use of insecticide-treated nets (ITNs) and indoor residual spraying (IRS) has contributed to the development of insecticide resistance in malaria vectors and shifts in biting patterns of the primary malaria vectors. The
Kennedy Zembere
doaj +1 more source
Background & objectives: Climate change is an emerging issue particularly in the context of vector-borne diseases. A study was undertaken in Nainital and Almora districts of Uttarakhand to provide evidences of changing climatic conditions, abundance of ...
Ramesh C Dhiman +8 more
doaj +1 more source
Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo +6 more
wiley +1 more source
PEG400 regulates Falcipain 2 activity through an allosteric mechanism
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath +2 more
wiley +1 more source

