Results 71 to 80 of about 38,153 (221)

History of the discovery of the malaria parasites and their vectors [PDF]

open access: yesParasites & Vectors, 2010
Malaria is caused by infection with protozoan parasites belonging to the genus Plasmodium transmitted by female Anopheles species mosquitoes. Our understanding of the malaria parasites begins in 1880 with the discovery of the parasites in the blood of malaria patients by Alphonse Laveran.
openaire   +4 more sources

Domination Versus Sisterhoods in the Blood Microbiota of Migrating Birds: Patterns of Within‐ and Between‐Individual Blood Parasite Diversity Revealed Through Metabarcoding

open access: yesIntegrative Zoology, EarlyView.
Avian haemosporidian blood parasites are typically identified through Sanger sequencing of a partial cytochrome b fragment, the MalAvi barcoding region. Next‐generation sequencing is seldom used for avian blood parasite identification; this study demonstrates a higher detection rate of co‐infections via metabarcoding and its possible implications ...
Peter Pibaque   +9 more
wiley   +1 more source

Predicting potential ranges of primary malaria vectors and malaria in northern South America based on projected changes in climate, land cover and human population

open access: yesParasites & Vectors, 2015
Background Changes in land use and land cover (LULC) as well as climate are likely to affect the geographic distribution of malaria vectors and parasites in the coming decades.
Temitope O. Alimi   +7 more
doaj   +1 more source

Urbanization and Vector Species Shape Avian Malaria Prevalence in Mosquitoes

open access: yesIntegrative Zoology, EarlyView.
Avian malaria prevalence was assessed in two mosquito species across urban and peri‐urban habitats. No infections were detected in either species in urban areas, while a 2.53% prevalence was found in the native Culex pipiens from peri‐urban sites, highlighting the influence of urbanization on parasite transmission dynamics.
Paula Parra   +5 more
wiley   +1 more source

Evidence of secondary anopheline vectors in sustaining malaria transmission in Kokrajhar District, Assam, Northeastern India

open access: yesParasites & Vectors
Background In the northeastern region of India, perennial malaria transmission persists in certain hotspots in areas geographically adjacent to the international borders with Bhutan, Bangladesh, and Myanmar, where both Plasmodium vivax and Plasmodium ...
Kuldeep Singh   +8 more
doaj   +1 more source

A Global Perspective of Childhood Vaccinations: Past, Present, and Future—From Smallpox to mRNA

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Childhood immunisation is one of the most successful public health interventions in history, preventing millions of deaths and substantially reducing global child mortality. This mini‐review summarises the historical development of childhood vaccines, the role of global coordination in expanding immunisation coverage, and the innovations that ...
Tobias Alfvén, Tania Reza, Alieu Sowe
wiley   +1 more source

The potential for attractive toxic sugar baits to complement core malaria interventions strategies: the need for more evidence

open access: yesMalaria Journal
Despite its success, the increased use of insecticide-treated nets (ITNs) and indoor residual spraying (IRS) has contributed to the development of insecticide resistance in malaria vectors and shifts in biting patterns of the primary malaria vectors. The
Kennedy Zembere
doaj   +1 more source

Preparedness for malaria elimination in the wake of climate change in the State of Uttarakhand (India)

open access: yesJournal of Vector Borne Diseases, 2019
Background & objectives: Climate change is an emerging issue particularly in the context of vector-borne diseases. A study was undertaken in Nainital and Almora districts of Uttarakhand to provide evidences of changing climatic conditions, abundance of ...
Ramesh C Dhiman   +8 more
doaj   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

open access: yesThe FEBS Journal, EarlyView.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo   +6 more
wiley   +1 more source

PEG400 regulates Falcipain 2 activity through an allosteric mechanism

open access: yesThe FEBS Journal, EarlyView.
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath   +2 more
wiley   +1 more source

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