Results 51 to 60 of about 487,671 (255)

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Viral vectors in malaria vaccine development [PDF]

Parasite Immunology, 2009
SummaryTraditional vaccine technologies have resulted in an impressive array of efficacious vaccines against a variety of infectious agents. However, several potentially deadly pathogens, including retroviruses and parasites, have proven less amenable to the application of traditional vaccine platforms, indicating the need for new approaches.
K J, Limbach, T L, Richie
openaire   +2 more sources

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

Electron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary, Harsh Sable, Sonu Sonu, Lakshita Phor, Reddicherla Umapathi, Pradeep Bhadola   +5 more
wiley   +1 more source

Pyrethroid resistance in Anopheles gambiae, in Bomi County, Liberia, compromises malaria vector control. [PDF]

, 2012
BACKGROUND: Long Lasting Insecticidal Nets (LLIN) and Indoor Residual Spraying (IRS) have both proven to be effective malaria vector control strategies in Africa and the new technology of insecticide treated durable wall lining (DL) is being evaluated ...
Avicor, Silas W, Silas W Avicor, Howard, Annabel F.V., Allan, Richard, Maxwell Caroline, Kleinschmidt, Immo, Richard Allan, Annabel F V Howard, Allan Richard, Munyekenye, Godwil, Caroline Maxwell, Emmanuel A Temu, Kleinschmidt Immo, Temu, Emmanuel A., Ranson, Hilary, Avicor, Silas W., Jones, Joel J., Temu Emmanuel A., Munga Stephen, Godwil Munyekenye, Joel J Jones, Howard Annabel F. V., Poupardin, Rodolphe, Temu, Emmanuel A, Howard, Annabel FV, Rodolphe Poupardin, Maxwell, Caroline, Avicor Silas W., Immo Kleinschmidt, Ranson, Hilary; id_orcid, Jones Joel J., Jones, Joel J, Stephen Munga, Munyekenye Godwil, Poupardin Rodolphe, Munga, Stephen, Hilary Ranson, Ranson Hilary   +37 more
core   +1 more source

The Impact of Domestic Public Health Spending on Health Outcomes in Sub‐Saharan Africa: Evidence From Disability‐Adjusted Life Years

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Sub‐Saharan Africa (SSA) continues to experience a high and uneven disease burden, mainly from HIV/AIDS, tuberculosis, and malaria. As external funding declines, the strategic allocation of domestic public health spending (DPHS) becomes crucial.
Wa Ntita Serge Kabongo, Josue Mbonigaba
wiley   +1 more source

Insecticide-treated nets can reduce malaria transmission by mosquitoes which feed outdoors. [PDF]

, 2010
Insecticide treated nets (ITNs) represent a powerful means for controlling malaria in Africa because the mosquito vectors feed primarily indoors at night.
Govella, Nicodem J, Killeen, Gerry F, Okumu, Fredros O   +2 more
core   +1 more source

Deubiquitinase USP38 Stabilizes PLK1 Expression to Boost DNA Damage Repair in Ovarian Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ovarian cancer (OC) is one of the most prevalent and severe gynecological malignant tumors. DNA damage repair (DDR) is essential in maintaining genome stability. This study aims to investigate the effects and mechanisms of USP38 and PLK1 on DNA damage repair and malignant behavior in OC cells.
Yuan Ma, Ying Li, Kai‐Li Li
wiley   +1 more source

Increasing role of Anopheles funestus and Anopheles arabiensis in malaria transmission in the Kilombero Valley, Tanzania [PDF]

, 2014
In order to sustain the gains achieved by current malaria control strategies, robust surveillance systems that monitor dynamics of vectors and their roles in malaria transmission over time are essential. This longitudinal study demonstrates the trends in
McCall, Philip; id_orcid, Dickson W Lwetoijera, Philip J McCall, McCall, Philip J., Harris, Caroline, Caroline Harris, Silas Majambere, Lwetoijera, Dickson W., Gregor J Devine, Stefan Dongus, Dongus, Stefan, Kiware, Samson S., Samson S Kiware, Devine, Gregor J., Majambere, Silas   +14 more
core   +1 more source

Impact of urbanization on the abundance and distribution of Anophelines population in Ghaziabad district, Uttar Pradesh, India

Journal of Vector Borne Diseases
Background & objectives: In urban areas, upsurge in population has resulted in more breeding sites for malaria vectors, and hence this scenario potentially undermine malaria elimination and control programs. The change in land use due to urbanization may
Alka Rani, Abhishek Gupta, BN Nagpal, Sanjeev Kumar Gupta, Anushrita, Pooja Prasad, Himmat Singh   +6 more
doaj   +1 more source

Malaria vectors in the world [PDF]

, 2021
Malaria is a severe disease caused by Plasmodium parasite species of which two - P. falciparum and P. vivax – are the most important for human. Despite the strong efforts made since the discovery of the aetiology, malaria is still a largely unresolved global public health problem, with 219 million cases in 90 countries estimated in 2017 (WHO Report ...
Romeo Bellini, Michele Dottori, Gianni Gilioli   +2 more
openaire