Results 51 to 60 of about 38,153 (221)

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva   +10 more
wiley   +1 more source

New gorilla adenovirus vaccine vectors induce potent immune responses and protection in a mouse malaria model

open access: yesMalaria Journal, 2017
Background A DNA-human Ad5 (HuAd5) prime-boost malaria vaccine has been shown to protect volunteers against a controlled human malaria infection. The potency of this vaccine, however, appeared to be affected by the presence of pre-existing immunity ...
Keith Limbach   +21 more
doaj   +1 more source

Long‐term impact of exposure to Royal Guard, a pyriproxyfen‐based bed net, on pyrethroid‐resistant malaria vectors from Cameroon using DNA‐based metabolic resistance markers

open access: yesPest Management Science, Volume 81, Issue 4, Page 2165-2180, April 2025.
We used recently detected P450 DNA‐based markers of pyrethroid resistance in both Anopheles funestus and Anopheles gambiae to demonstrate that although pyrethroid‐resistant mosquitoes have higher ability to survive and live longer after exposure to Royal Guard, this net significantly affects their lifespan, blood feeding ability and interestingly ...
Emilie S Ngongang‐Yipmo   +8 more
wiley   +1 more source

Secondary malaria vectors in western Kenya include novel species with unexpectedly high densities and parasite infection rates

open access: yesParasites & Vectors, 2021
Background Malaria vector control has been implemented chiefly through indoor interventions targeting primary vectors resulting in population declines—pointing to a possible greater proportional contribution to transmission by secondary malaria vectors ...
Amine M. Mustapha   +7 more
doaj   +1 more source

Illegal Gold Mining in the Brazilian Amazon: Environmental Degradation in Yanomami Indigenous Lands, and Regulatory Failures

open access: yesSustainable Development, EarlyView.
ABSTRACT Illegal gold mining has emerged as a major sustainability threat in the Amazon, eroding Indigenous rights, forest integrity, and climate mitigation efforts. This study examines how international market incentives relate to the expansion of illegal mining and associated deforestation within the Yanomami Indigenous Territory (YIT) from 2008 to ...
Shirléia Lago Santos   +2 more
wiley   +1 more source

Spatio-temporal analysis of malaria vectors in national malaria surveillance sites in China

open access: yesParasites & Vectors, 2015
Background To reveal the spatio-temporal distribution of malaria vectors in the national malaria surveillance sites from 2005 to 2010 and provide reference for the current National Malaria Elimination Programme (NMEP) in China.
Ji-Xia Huang   +10 more
doaj   +1 more source

Influence of pyrethroïd-treated bed net on host seeking behavior of Anopheles gambiae s.s. carrying the kdr allele. [PDF]

open access: yesPLoS ONE, 2017
The use of long lasting insecticide nets (LLINs) treated with pyrethroïd is known for its major contribution in malaria control. However, LLINs are suspected to induce behavioral changes in malaria vectors, which may in turn drastically affect their ...
Angélique Porciani   +7 more
doaj   +1 more source

Malaria vector control in South Africa

open access: yesSouth African Medical Journal, 2013
Malaria vector control is primarily insecticide based and relies on indoor residual spraying (IRS) and the distribution of long-lasting insecticide-treated bednets (LLINs). These interventions have generally proved effective where appropriately implemented.
Brooke, B   +5 more
openaire   +5 more sources

Twenty‐one questions shaping the future of plant phenology research in the 21st century

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract This Perspective examines the critical frontiers shaping the future of plant phenology research and identifies key emerging challenges and opportunities expected to influence the field in the 21st century.
Barbara Templ   +19 more
wiley   +1 more source

Assessing insecticide susceptibility status of Anopheles mosquitoes in Gondar zuria district, Northwest Ethiopia

open access: yesScientific Reports
Insecticide-based vector control, which comprises the use of insecticide-treated bed nets (ITNs) and indoor residual spraying (IRS), is the key method of malaria control in Ethiopia.
Silesh Barasa   +7 more
doaj   +1 more source

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