Results 121 to 130 of about 236,694 (244)

Blood Cell Counts and the Duffy Null Phenotype: Beyond Neutropenia

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT The absence of Duffy antigen expression on red blood cells, caused by a single nucleotide polymorphism in the DARC/ACKR1 gene, confers protection against malaria and is associated with lower absolute neutrophil counts (ANC) in some studied populations.
Elvira Deolinda R. P. Velloso, Andreza Oliveira dos Santos, Carla Luana Dinardo, Carolina Bonet Bub, Leandro Dinalli Santos, Mauren Fernanda Moller dos Santos, João Carlos de Campos Guerra, Denise dos Anjos Laurentis de Sousa Campos, Monica Juliana Vieira, Fábio Julio da Luz, Alfredo Mendrone‐Junior, Rosana M. Cosentino Penteado   +11 more
wiley   +1 more source

The Plasmodium falciparum sexual development transcriptome: a microarray analysis using ontology-based pattern identification.

, 2005
The sexual stages of malarial parasites are essential for the mosquito transmission of the disease and therefore are the focus of transmission-blocking drug and vaccine development.
Young, Jason A, Baker, David A, Zhou, Yingyao, de la Vega, Patricia, Fivelman, Quinton L, Blair, Peter L, Winzeler, Elizabeth A, Le Roch, Karine G, Carucci, Daniel J   +8 more
core   +1 more source

Anaemia Among Mother–Child Dyads in India: Trends, Drivers, and Future Projections

Maternal &Child Nutrition, EarlyView.
ABSTRACT Anaemia among mothers and their children is a widespread public health challenge with profound consequences for individuals and societies. While anaemia has been studied separately in women and children, there remains a literature gap examining anaemia in mother‐child dyads, limiting insights on interventions that may simultaneously address ...
Sarang Pedgaonker, Trupti Meher, Monali Gupta, Suman Chakrabarti, Phuong Hong Nguyen, Shri Kant Singh, Laxmi Kant Dwivedi, Aditi, Samuel Scott   +8 more
wiley   +1 more source

The role of lipid in malaria pigment (Haemozoin) formation under biomimetic conditions [PDF]

, 2013
Includes bibliographical references.Previous studies have proposed lipids and/or proteins to be involved in the biomineralization process of haemozoin formation in the malaria parasite which is a target for many antimalarial drugs.
Ambele, Melvin Anyasi
core   +1 more source

Effects of Video‐Based Health Education on Birth Outcomes and Anaemia Status of Mothers in Dirashe District South Ethiopia: A Cluster Randomized Controlled Trial

Maternal &Child Nutrition, EarlyView.
ABSTRACT Undernutrition and infections during pregnancy result in low birth weight (LBW) and maternal anaemia. Social behaviour change communication (SBCC) can promote recommended health practices, potentially improving maternal and neonatal outcomes.
Wanzahun Godana Boynito, Kidus Temesgen Worsa, Befikadu Tariku Gutema, Yordanos Gizachew Yeshitila, Godana Yaya Tessema, Tsegaye Yohanis, Stefaan De Henauw, Piet Cools, Bruno Levecke, Souheila Abbeddou   +9 more
wiley   +1 more source

A Genetically Encoded Marker for Imaging of Internal Plasmodium Membranes

Molecular Microbiology, EarlyView.
IMMP is a peptide‐based marker that labels internal membranes across multiple stages and species of the malaria‐causing parasite Plasmodium. It works in both live and fixed samples and supports long‐term live‐cell imaging. ABSTRACT Fluorescence microscopy is a powerful tool to analyze the subcellular architecture, and long‐term live‐cell imaging ...
Leah Zink, Viola Reuschenbach, Samy Sid Ahmed, Muriel Lauer, Jana Niethammer, Aistė Kudulytė, Katharina Zorko, Oliver T. Fackler, Franziska Hentzschel, Markus Ganter   +9 more
wiley   +1 more source

Characterization of Sec14 Domain–Containing Proteins in the Malaria Parasite Plasmodium falciparum

Molecular Microbiology, EarlyView.
During asexual blood‐stage development, P. falciparum Sec14 proteins display distinct localizations suggesting specialized roles in lipid exchange. PfSec14‐1 initially localizes to the nucleus before moving to the ER and Golgi alongside PfSec14‐4 during schizogony.
Florian Lauruol, Dominik Šťastný, J. Pedro Fernandez‐Murray, Christopher R. McMaster, Peter Griač, Dave Richard   +5 more
wiley   +1 more source

Plasmodium Actin‐Like Proteins 3 and 5a Are Required for Subsequent Steps of Mosquito Infection

Molecular Microbiology, EarlyView.
Actin‐like proteins (Alps) are highly conserved, apicomplexan‐specific members of the actin superfamily. Using reverse genetics, we have identified that Alp3 and Alp5a are required at separate steps of transmission of the malaria parasite to its mosquito host.
Caroline Busse, Yukino Kobayashi, Andrea Diers, Annika M. Binder, Friedrich Frischknecht, Ross G. Douglas   +5 more
wiley   +1 more source

Addressing Behavioural Determinants of Cutaneous Leishmaniasis Through Community Dialogue in Kalu District, Ethiopia: A Mixed‐Methods Study

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background Cutaneous leishmaniasis (CL) is a major public health challenge in Ethiopia, with 20–30,000 new cases annually. Limited awareness and misconceptions contribute to delayed care seeking, stigma, prolonged healing, and reduced uptake of preventive measures in CL‐endemic communities.
Takele Gezahegn Demie, Tara Mtuy, Jennifer Palmer, Eshetu Girma, Yohannes Hailemichael, Teklu Cherkose, Telahun Kasa Tefera, Mohammedjud Hassen Ahmed, Catherine Pitt, Michael Marks, Stephen L. Walker, Endalamaw Gadisa, Mirgissa Kaba, SHARP collaboration   +13 more
wiley   +1 more source

Hotspots in Plasmodium and RBC Receptor-Ligand Interactions: Key Pieces for Inhibiting Malarial Parasite Invasion. [PDF]

Int J Mol Sci, 2020
Patarroyo MA, Molina-Franky J, Gómez M, Arévalo-Pinzón G, Patarroyo ME.   +4 more
europepmc   +1 more source