Results 131 to 140 of about 236,694 (244)

Plasmodium falciparum Parasites With Histidine‐Rich Protein 2 (pfhrp2) and pfhrp3 Gene Deletions in Frontier Endemic Regions of Brazilian Amazon

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Studies reporting deletions of the pfhrp2 and pfhrp3 genes in P. falciparum populations in various malaria‐endemic countries, including countries bordering Brazil, are increasing. Individuals infected with P. falciparum carrying deletions of the pfhrp2/3 genes may yield false‐negative results in Rapid Diagnostic Tests (RDTs) based on the ...
Jéssica de Oliveira Bonsanto Gonçalves   +9 more
wiley   +1 more source

Donor management implications for high‐sensitivity detection of low‐level malaria parasitemia in blood donor screening

open access: yesTransfusion, EarlyView.
Abstract Introduction Transfusion‐transmitted malaria can occur when donors have unrecognized asymptomatic infection with submicroscopic parasitemia, highlighting the need to detect low‐level parasitemia in blood donor screening. However, these highly sensitive blood donor testing algorithms may refer donors to clinicians who use diagnostic algorithms ...
Carmen L. Charlton   +8 more
wiley   +1 more source

Molecular characterization of CD36 deficiency in blood donors of Middle Eastern and African origin reveals transcript‐level defects beyond genomic variants

open access: yesTransfusion, EarlyView.
Abstract Background The increasing diversity of blood donor populations has created new challenges for transfusion services worldwide. The identification of donors lacking relevant high‐prevalence antigens is becoming increasingly important to ensure compatible blood products for alloimmunized patients and to support the development of rare donor ...
Sarah Petermann   +7 more
wiley   +1 more source

Budget impact of implementing universal Plasmodium NAT screening in the blood transfusion system in the US

open access: yesTransfusion, EarlyView.
Abstract Background Blood donor deferral for malaria risk relies exclusively on responses to self‐reported questionnaires. This study evaluated the economic impact of introducing Plasmodium nucleic acid testing (NAT) as a universal screening strategy in the United States.
Cristina Coll‐Ortega   +3 more
wiley   +1 more source

Public perspectives on potential changes to malaria deferral criteria in Canada

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives As blood collection agencies (BCAs) seek to increase donor diversity, making changes to eligibility criteria to enable more people to donate is an important consideration. BCAs in Canada have a permanent deferral from whole blood and platelet donation for anyone with a history of malaria, a barrier to donation for ...
Courtney Joshua   +4 more
wiley   +1 more source

Differential Effect of Ivermectin on Intestinal Helminths in Multimmate Mouse (Mastomys natalensis)

open access: yesVeterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Mastomys natalensis harbours gastrointestinal helminths of public health and food‐safety importance. This study identified five helminth taxa and assessed faecal egg counts after a single ivermectin dose. Egg counts declined substantially in treated rodents but changed little in controls over eight weeks.
Claus Thomas   +9 more
wiley   +1 more source

Autoantibodies to Extracellular Erythrocyte Band 3 Epitopes Are Associated With Anemia in Plasmodium vivax Infection

open access: yesAmerican Journal of Hematology, Volume 101, Issue 10, Page 2592-2604, October 2026.
ABSTRACT Plasmodium vivax‐associated anemia is a multifactorial clinical outcome, in which the destruction of uninfected red blood cells (uRBCs) plays a major role in disease development and severity. Here, we identified autoantibody targets within the extracellular loops of Band 3 (B3), a major erythrocyte transmembrane protein.
Aline Marzano‐Miranda   +6 more
wiley   +1 more source

Developmental Toxicity Study for the Antimalarial Drug Combination Cabamiquine‐Pyronaridine Using a Translational Approach

open access: yesBirth Defects Research, Volume 118, Issue 10, October 2026.
ABSTRACT Background The safety of pharmacological treatments during pregnancy is a significant concern, as many medications lack comprehensive reproductive safety data. This creates gaps in therapeutic options for pregnant women, particularly malaria, which poses serious risks to maternal and fetal health.
Wookyung Kim   +9 more
wiley   +1 more source

Severe Plasmodium vivax Malaria Complicated by Secondary Hemophagocytic Lymphohistiocytosis, Disseminated Intravascular Coagulation, and Acute Pancreatitis: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Plasmodium vivax (P. vivax) malaria, once regarded as a comparatively benign infection, is increasingly recognized as a cause of severe, potentially life‐threatening multisystem disease. Concurrent secondary hemophagocytic lymphohistiocytosis (HLH), disseminated intravascular coagulation (DIC), and acute pancreatitis complicating P.
Tasnim Nafian   +5 more
wiley   +1 more source

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