Results 141 to 150 of about 236,694 (244)

Impact of Sickle Cell Hemoglobin Genotypes on Clinical Outcomes Among Plasmodium falciparum Malaria Patients in Luanda, Angola

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Sickle cell anemia (SCA) may influence malaria susceptibility and clinical outcomes in endemic regions. However, the interaction between hemoglobin genotypes and malaria severity remain poorly defined in endemic African settings, particulary in Angola, where SCA and malaria impose a substantial public health burden.
Cruz S. Sebastião, Eduardo Ekundi‐Valentim, Edson Cassinela, Euclides Sacomboio   +3 more
wiley   +1 more source

Explainable Machine Learning for Predicting Global Malaria Incidence From 2000 to 2022 With Climatic and Extreme Weather Conditions Across 78 Endemic Countries: A Retrospective Ecological Study

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims Malaria remains a major global health concern, causing substantial morbidity and mortality, especially in tropical and subtropical regions with limited healthcare resources. Climatic conditions and extreme weather events are increasingly recognized as critical determinants of malaria transmission, yet their relative ...
Md. Abu Bokkor Shiddik, Md. Abdullah Al Fahad Sohan   +1 more
wiley   +1 more source

Community‐Centric Malaria Prevention in Sub‐Saharan Africa: A Narrative Review of Pathways to Elimination and Global Health Impact

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims Malaria remains a major global health challenge, with the World Health Organization (WHO) African Region accounting for the overwhelming majority of malaria cases and deaths worldwide. This narrative review examines the contribution of community‐centric malaria prevention approaches to malaria elimination pathways and their
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Pre-clinical study of iron oxide nanoparticles fortified artesunate for efficient targeting of malarial parasite. [PDF]

EBioMedicine, 2019
Kannan D, Yadav N, Ahmad S, Namdev P, Bhattacharjee S, Lochab B, Singh S.   +6 more
europepmc   +1 more source

Characterisation of Typical Enteropathogenic Escherichia coli (tEPEC) and bfpA Genes From Five Bat Species Reveals Australian Pteropus Spp. Are Natural tEPEC Hosts

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
This study revealed that Australia's five Pteropus bat species are all natural hosts of typical Enteropathogenic Escherichia coli (tEPEC)—historically considered a human‐specific pathogen. Across the five Pteropus spp., tEPEC prevalence ranged between 14.2% and 37.0%, with 18 bat‐specific tEPEC strain types and 24 bat‐specific bfpA allele types ...
Fiona K. McDougall, Laura A. Pulscher, Wayne S. J. Boardman, Karrie Rose, Mariel Fulham, Michelle L. Power   +5 more
wiley   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 10, Page 1686-1701, October 2026.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source

Assessing the Use of Oxford Nanopore Technologies Sequencing for Detection of Stable Wolbachia Bacterial Strain in Symbiosis in Wild Anopheles Mosquitoes From the WHO African Region

Environmental Microbiology, Volume 28, Issue 10, October 2026.
This study assesses Oxford Nanopore Technology sequencing to detect Wolbachia in Anopheles mosquitoes. To do this, samples were analysed using the ONT field sequencing kit and sequenced using a minION flow cell and the ONT 16S barcoding kit and Rapid barcoding kit sequenced using Flongle flow cells.
Laura Chatterley, Nicola Hull, Isabel Hughes, Seynabou Sougoufara, Owain Meek, Murat Ceyran, Vishaal Dhokiya, Janvier Bandibabone, Cyprian Adala, Elin Cunningham, Shehu Shagari Awandu, Helene Kaminski‐Nenkam, Antonio Nkondjio, Grant L. Hughes, Eva Heinz, Thomas Walker   +15 more
wiley   +1 more source

Preventing Invasive Non‐Native Species: A Horizon Scanning for the Canary Islands

Diversity and Distributions, Volume 32, Issue 10, October 2026.
ABSTRACT Aim Oceanic islands host exceptional biodiversity and endemism but are highly vulnerable to biological invasions. We aimed to identify non‐native species with high potential to invade the Canary Islands within the next decade and to prioritise them based on their environmental and socioeconomic risks.
Ana Clara Sampaio Franco, Carolina Mendes Muniz, Martina Carrete, Pilar Castro‐Díez, Miguel Delibes‐Mateos, Josep A. Jaques, Mar Leza, Marta López‐Darias, Manuel Nogales, Macarena Ros, Xavier Turon, Montserrat Vilà, Óscar Afonso, Inés Álvarez, Andrés Arias, Dani Boix, Carlos Cabido, Eva Cacabelos, Carlos Cano‐Barbacil, Miguel Cañedo‐Argüelles, Beatriz Dáder, Ramón Gallo‐Barneto, Ignacio Gestoso, María González Díaz, David Hernández‐Teixidor, José Carlos Hernández, Cayetano Herrera, Marc Martín Solà, Elizabeth Ojeda‐Land, Francisco J. Oliva‐Paterna, Miguel Antonio Padrón‐Mederos, Jairo Patiño, Laura Piñeiro, Núria Roura‐Pascual, Marcos Salas‐Pascual, Elisa Viñuela, Emili García‐Berthou   +36 more
wiley   +1 more source

Malaria mosquito antimicrobial defence requires immunity and detoxification gene regulation by Lola

Insect Molecular Biology, Volume 35, Issue 5, Page 576-593, October 2026.
Malaria mosquito antimicrobial defence requires upregulation of lola. Attenuation of lola in the midgut of Anopheles albimanus mosquitoes inhibits the upregulation of immunity genes induced by challenge. Putative target genes of the Lola transcription factor were revealed by lola attenuation, including Cecropin‐C, Draper, PPAF2, Clip‐domain serine ...
Heidi Espadas‐Álvarez, Verónica Valverde‐Garduño   +1 more
wiley   +1 more source

Copper Homeostasis for the Developmental Progression of Intraerythrocytic Malarial Parasite. [PDF]

Curr Top Med Chem, 2016
Asahi H, Kobayashi F, Inoue SI, Niikura M, Yagita K, Tolba ME.   +5 more
europepmc   +1 more source