Results 31 to 40 of about 236,694 (244)

The Mosquito and the Malarial Parasite [PDF]

The American Journal of the Medical Sciences, 1898
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openaire   +1 more source

Identification of proteins targeted by the thioredoxin superfamily in Plasmodium falciparum. [PDF]

, 2009
The malarial parasite Plasmodium falciparum possesses a functional thioredoxin and glutathione system comprising the dithiol-containing redox proteins thioredoxin (Trx) and glutaredoxin (Grx), as well as plasmoredoxin (Plrx), which is exclusively found ...
Sturm, Nicole, Becker Katja, Koncarevic, Sasa, Forchhammer, Karl, Mailu, Boniface M., Rahlfs, Stefan, Katja Becker, Deponte, Marcel, Koncarevic Sasa, Becker, Katja, Sturm Nicole, Mailu Boniface M., Marcel Deponte, Deponte Marcel, Jortzik, Esther, Stefan Rahlfs, Jortzik Esther, Esther Jortzik, Karl Forchhammer, Nicole Sturm, Forchhammer Karl, Boniface M Mailu, Sasa Koncarevic, Rahlfs Stefan   +23 more
core   +2 more sources

Lactate levels in severe malarial anaemia are associated with haemozoin-containing neutrophils and low levels of IL-12

Malaria Journal, 2006
Background Hyperlactataemia is often associated with a poor outcome in severe malaria in African children. To unravel the complex pathophysiology of this condition the relationship between plasma lactate levels, parasite density, pro- and anti ...
Williams Thomas N, English Mike, Lowe Brett, Kai Oscar, Casals-Pascual Climent, Maitland Kathryn, Newton Charles RCJ, Peshu Norbert, Roberts David J   +8 more
doaj   +1 more source

2D-quantitative structure–activity relationships model using PLS method for anti-malarial activities of anti-haemozoin compounds

Malaria Journal, 2021
Background Emergence of cross-resistance to current anti-malarial drugs has led to an urgent need for identification of potential compounds with novel modes of action and anti-malarial activity against the resistant strains.
Phuong Thuy Viet Nguyen, Truong Van Dat, Shusaku Mizukami, Duy Le Hoang Nguyen, Farhana Mosaddeque, Son Ngoc Kim, Duy Hoang Bao Nguyen, Oanh Thi Đinh, Tu Linh Vo, Giang Le Tra Nguyen, Cuong Quoc Duong, Satoshi Mizuta, Dao Ngoc Hien Tam, M. Phuong Truong, Nguyen Tien Huy, Kenji Hirayama   +15 more
doaj   +1 more source

THE MALARIAL PARASITE AND HEMOGLOBINURIA [PDF]

Southern Medical Journal, 1913
n ...
openaire   +2 more sources

Parasite genetic diversity does not influence TNF-mediated effects on the virulence of primary rodent malaria infections [PDF]

, 2006
The pro-inflammatory cytokine tumour necrosis factor alpha (TNF-alpha) is associated with malaria virulence (disease severity) in both rodents and humans.
Long, G H, Read, A F, Read, A. F., Chan, Brian, Long, G. H., Graham, Andrea, A. F. READ, G. H. LONG, Allen, J. E., Chan, B H K, A. L. GRAHAM, J. E. ALLEN, Allen, Judith, Graham, A. L., Allen, J E, Graham, A L, B. H. K. CHAN, Read, Andrew F, Chan, B. H K; id_orcid, Long, Gráinne Helen   +19 more
core   +1 more source

Impact of intermittent preventive anti-malarial treatment on the growth and nutritional status of preschool children in rural Senegal (west Africa). [PDF]

, 2007
Negative consequences of malaria might account for seasonality in nutritional status in children in the Sahel. We report the impact of a randomized, double-blind, placebo-controlled trial of seasonal intermittent preventive anti-malarial treatment on ...
Greenwood, Brian M, Boulanger, Denis, Lines, Jo, Cissé, Badara, Alexander, N., Lines, J., Simondon, François, Simondon, Kirsten B, Greenwood, B. M., Sokhna, Cheikh, Targett, G., Simondon, Kirsten, Alexander, Neal, Trape, Jean-François, Ntab, Balthazar, Targett, Geoffrey   +15 more
core   +1 more source

Sex ratios in the rodent malaria parasite, Plasmodium chabaudi [PDF]

, 2003
The sex ratios of malaria and related Apicomplexan parasites play a major role in transmission success. Here, we address 2 fundamental issues in the sex ratios of the rodent malaria parasite, Plasmodium chabaudi.
West, SA, West, S A, Read, A F, REECE, S. E., West, S. A., Read, A. F., Duncan, A B, West, Stuart A, Reece, S E, Duncan, A., Reece, SE, Duncan, AB, Read, AF, Duncan, Alison B, Read, Andrew F   +14 more
core   +1 more source

Biophysics of malarial parasite exit from infected erythrocytes. [PDF]

PLoS ONE, 2011
Upon infection and development within human erythrocytes, P. falciparum induces alterations to the infected RBC morphology and bio-mechanical properties to eventually rupture the host cells through parasitic and host derived proteases of cysteine and ...
Rajesh Chandramohanadas, YongKeun Park, Lena Lui, Ang Li, David Quinn, Kingsley Liew, Monica Diez-Silva, Yongjin Sung, Ming Dao, Chwee Teck Lim, Peter Rainer Preiser, Subra Suresh   +11 more
doaj   +1 more source

The Plasmodium falciparum exported J domain proteins fine-tune human and malarial Hsp70s: pathological exploitation of proteostasis machinery

Frontiers in Molecular Biosciences, 2023
Cellular proteostasis requires a network of molecular chaperones and co-chaperones, which facilitate the correct folding and assembly of other proteins, or the degradation of proteins misfolded beyond repair.
Shaikha Y. Almaazmi, Rupinder P. Kaur, Harpreet Singh, Gregory L. Blatch, Gregory L. Blatch   +4 more
doaj   +1 more source