Results 21 to 30 of about 25,729 (205)

Anti-malarial activity of the alkaloid, heptaphylline, and the furanocoumarin, imperatorin, from Clausena anisata against human Plasmodium falciparum malaria parasites: ex vivo trophozoitocidal, schizonticidal and gametocytocidal approach

Malaria Journal, 2023
Background The erythrocytic stage of the life cycle of the malaria parasite, Plasmodium falciparum, consists of trophozoite, schizont and gametocyte stages in humans.
Emmanuel Kofi Kumatia, Felix Kwame Zoiku, Alex Asase, Nguyen Huu Tung   +3 more
doaj   +1 more source

Targeting proteases and proteolytic processing of unusual N-terminal extensions of Plasmodium proteins: parasite peculiarity

Frontiers in Drug Discovery, 2023
More than sesquicentennial years of malarial research, however the unique malarial parasite, Plasmodium still bewilders us with its atypical characteristic features.
Ankita Tehlan, Abhik Saha, Abhik Saha, Suman Kumar Dhar   +3 more
doaj   +1 more source

DIAGNOSIS OF MALARIA BY REAL-TIME POLYMERASE CHAIN REACTION IN CASES OF NEGATIVE MALARIAL PARASITE ON MICROSCOPY

Pakistan Armed Forces Medical Journal, 2020
Objective: To determine the frequency of malaria by polymerase chain reaction in malarial parasite negative samples on microscopy. Study Design: Cross-sectional study.
Hina Mushtaq, Mariam Raza, Makki Muhammad, Tarique Arian, Imran Khan, Nighat Afridi   +5 more
doaj   +4 more sources

The flagellum in malarial parasites

Current Opinion in Microbiology, 2010
The malarial parasites assemble flagella exclusively during the formation of the male gamete in the midgut of the female mosquito vector. The observation of gamete formation ex vivo reported by Laveran (Laveran MA: De la nature parasitaire des accidents de l'impaludisme. Comptes Rendues De La Societe de Biologie.
Sinden, R, Talman, A, Marques, SR, Wass, M, Sternberg, M   +4 more
openaire   +2 more sources

The Mosquito and the Malarial Parasite [PDF]

The American Journal of the Medical Sciences, 1898
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openaire   +1 more source

Lactate levels in severe malarial anaemia are associated with haemozoin-containing neutrophils and low levels of IL-12

Malaria Journal, 2006
Background Hyperlactataemia is often associated with a poor outcome in severe malaria in African children. To unravel the complex pathophysiology of this condition the relationship between plasma lactate levels, parasite density, pro- and anti ...
Williams Thomas N, English Mike, Lowe Brett, Kai Oscar, Casals-Pascual Climent, Maitland Kathryn, Newton Charles RCJ, Peshu Norbert, Roberts David J   +8 more
doaj   +1 more source

2D-quantitative structure–activity relationships model using PLS method for anti-malarial activities of anti-haemozoin compounds

Malaria Journal, 2021
Background Emergence of cross-resistance to current anti-malarial drugs has led to an urgent need for identification of potential compounds with novel modes of action and anti-malarial activity against the resistant strains.
Phuong Thuy Viet Nguyen, Truong Van Dat, Shusaku Mizukami, Duy Le Hoang Nguyen, Farhana Mosaddeque, Son Ngoc Kim, Duy Hoang Bao Nguyen, Oanh Thi Đinh, Tu Linh Vo, Giang Le Tra Nguyen, Cuong Quoc Duong, Satoshi Mizuta, Dao Ngoc Hien Tam, M. Phuong Truong, Nguyen Tien Huy, Kenji Hirayama   +15 more
doaj   +1 more source

THE MALARIAL PARASITE AND HEMOGLOBINURIA [PDF]

Southern Medical Journal, 1913
n ...
openaire   +2 more sources

The Plasmodium falciparum exported J domain proteins fine-tune human and malarial Hsp70s: pathological exploitation of proteostasis machinery

Frontiers in Molecular Biosciences, 2023
Cellular proteostasis requires a network of molecular chaperones and co-chaperones, which facilitate the correct folding and assembly of other proteins, or the degradation of proteins misfolded beyond repair.
Shaikha Y. Almaazmi, Rupinder P. Kaur, Harpreet Singh, Gregory L. Blatch, Gregory L. Blatch   +4 more
doaj   +1 more source

The biology of malarial parasite in the mosquito: a review

Memorias do Instituto Oswaldo Cruz, 1996
The purpose of this review is to summarize the biology of Plasmodium in the mosquito including recent data to contribute to better understanding of the developmental interaction between mosquito and malarial parasite.
Amauri Braga Simonetti
doaj   +1 more source