Results 41 to 50 of about 236,694 (244)

Major reduction in anti-malarial drug consumption in Senegal after nation-wide introduction of malaria rapid diagnostic tests. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: While WHO recently recommended universal parasitological confirmation of suspected malaria prior to treatment, debate has continued as to whether wide-scale use of rapid diagnostic tests (RDTs) can achieve this goal.
Sylla Thiam   +13 more
doaj   +1 more source

ANTI-MALARIAL COMPOUND FROM THE STEM BARK OF Erythrina variegata

open access: yesIndonesian Journal of Chemistry, 2010
During the course of our continuing search for novel anti-malarial compounds from Indonesian plants, the methanol extract of the bark of E. variegata showed significant anti-malarial activity toward Plasmodium falciparum in vitro using the lactate ...
Tati Herlina   +6 more
doaj   +1 more source

Transcriptional mediators Kto and Skd are involved in the regulation of the IMD pathway and anti-Plasmodium defense in Anopheles gambiae. [PDF]

open access: yesPLoS ONE, 2012
The malarial parasite Plasmodium must complete a complex lifecycle in its Anopheles mosquito host, the main vector for Plasmodium. The mosquito resists infection with the human malarial parasite P.
Yang Chen   +3 more
doaj   +1 more source

MALARIAL PARASITE

open access: yesThe Professional Medical Journal, 2009
Objectives: To determine the slide positivity rate and to document the different species of malarial parasite at district Shikarpur,Sindh, Pakistan. D e s i g n : A retrospective study. Setting: This study was conducted at district Malaria control centre Shikarur with collaborationof Pathology Department CMC Larkana and Leishmaniaisis/Mosquito Zoology ...
FAROOQ RAHMAN SOOMRO   +2 more
openaire   +2 more sources

Novos conceitos na esplenomegalia malárica hiperreactiva.

open access: yesActa Médica Portuguesa, 2003
Hyperreactive malarial splenomegaly is thought to represent an immunological dysfunction due to recurrent episodes of malaria. The authors present a case of hyperreactive malarial splenomegaly in a patient from São Tomé e Príncipe and discuss aspects of ...
M F Moraes   +5 more
doaj   +1 more source

Selective inhibition of PfA-M1, over PfA-M17, by an amino-benzosuberone derivative blocks malaria parasites development in vitro and in vivo

open access: yesMalaria Journal, 2017
Background Plasmodium falciparum M1 family aminopeptidase is currently considered as a promising target for anti-malarial chemotherapy. Several series of inhibitors developed by various research groups display IC50/Ki values down to nM range on native ...
Lotfi Bounaadja   +5 more
doaj   +1 more source

Mathematical model of detection of intra-erythrocyte pathologies using optoacoustic method

open access: yesBiomedical Photonics, 2018
Malaria causes a serious health problem in the tropical and subtropical regions of the globe. In many cases, the consequences of this disease are fatal. Therefore, a simple, fast, accurate and affordable diagnostic system for the early detection of this ...
D. A. Kravchuk
doaj   +1 more source

Anti-malarial Drug Design by Targeting Apicoplasts: New Perspectives

open access: yesJournal of Pharmacopuncture, 2016
Objectives: Malaria has been a major global health problem in recent times with increasing mortality. Current treatment methods include parasiticidal drugs and vaccinations.
Avinaba Mukherjee   +1 more
doaj   +1 more source

National-scale simulation of human movement in a spatially coupled individual-based model of malaria in Burkina Faso

open access: yesScientific Reports, 2023
Malaria due to the Plasmodium falciparum parasite remains a threat to human health despite eradication efforts and the development of anti-malarial treatments, such as artemisinin combination therapies.
Robert J. Zupko   +4 more
doaj   +1 more source

Splenic Tropism and Spleen‐Modulated Systemic Inflammation in Acute Plasmodium vivax Malaria

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT In chronic Plasmodium vivax (Pv) infection, the spleen accounts for over 98% of total‐body parasite biomass. Whether splenic tropism also occurs in acute infection and how the spleen influences pathogenesis have not been systematically explored. In Papua, Indonesia, we compared clinical and hematology data in 24 spleen‐intact and 25 previously
Steven Kho   +27 more
wiley   +1 more source

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