Results 41 to 50 of about 236,694 (244)
Major reduction in anti-malarial drug consumption in Senegal after nation-wide introduction of malaria rapid diagnostic tests. [PDF]
BACKGROUND: While WHO recently recommended universal parasitological confirmation of suspected malaria prior to treatment, debate has continued as to whether wide-scale use of rapid diagnostic tests (RDTs) can achieve this goal.
Sylla Thiam +13 more
doaj +1 more source
ANTI-MALARIAL COMPOUND FROM THE STEM BARK OF Erythrina variegata
During the course of our continuing search for novel anti-malarial compounds from Indonesian plants, the methanol extract of the bark of E. variegata showed significant anti-malarial activity toward Plasmodium falciparum in vitro using the lactate ...
Tati Herlina +6 more
doaj +1 more source
Transcriptional mediators Kto and Skd are involved in the regulation of the IMD pathway and anti-Plasmodium defense in Anopheles gambiae. [PDF]
The malarial parasite Plasmodium must complete a complex lifecycle in its Anopheles mosquito host, the main vector for Plasmodium. The mosquito resists infection with the human malarial parasite P.
Yang Chen +3 more
doaj +1 more source
Objectives: To determine the slide positivity rate and to document the different species of malarial parasite at district Shikarpur,Sindh, Pakistan. D e s i g n : A retrospective study. Setting: This study was conducted at district Malaria control centre Shikarur with collaborationof Pathology Department CMC Larkana and Leishmaniaisis/Mosquito Zoology ...
FAROOQ RAHMAN SOOMRO +2 more
openaire +2 more sources
Novos conceitos na esplenomegalia malárica hiperreactiva.
Hyperreactive malarial splenomegaly is thought to represent an immunological dysfunction due to recurrent episodes of malaria. The authors present a case of hyperreactive malarial splenomegaly in a patient from São Tomé e Príncipe and discuss aspects of ...
M F Moraes +5 more
doaj +1 more source
Background Plasmodium falciparum M1 family aminopeptidase is currently considered as a promising target for anti-malarial chemotherapy. Several series of inhibitors developed by various research groups display IC50/Ki values down to nM range on native ...
Lotfi Bounaadja +5 more
doaj +1 more source
Mathematical model of detection of intra-erythrocyte pathologies using optoacoustic method
Malaria causes a serious health problem in the tropical and subtropical regions of the globe. In many cases, the consequences of this disease are fatal. Therefore, a simple, fast, accurate and affordable diagnostic system for the early detection of this ...
D. A. Kravchuk
doaj +1 more source
Anti-malarial Drug Design by Targeting Apicoplasts: New Perspectives
Objectives: Malaria has been a major global health problem in recent times with increasing mortality. Current treatment methods include parasiticidal drugs and vaccinations.
Avinaba Mukherjee +1 more
doaj +1 more source
Malaria due to the Plasmodium falciparum parasite remains a threat to human health despite eradication efforts and the development of anti-malarial treatments, such as artemisinin combination therapies.
Robert J. Zupko +4 more
doaj +1 more source
Splenic Tropism and Spleen‐Modulated Systemic Inflammation in Acute Plasmodium vivax Malaria
ABSTRACT In chronic Plasmodium vivax (Pv) infection, the spleen accounts for over 98% of total‐body parasite biomass. Whether splenic tropism also occurs in acute infection and how the spleen influences pathogenesis have not been systematically explored. In Papua, Indonesia, we compared clinical and hematology data in 24 spleen‐intact and 25 previously
Steven Kho +27 more
wiley +1 more source

