Results 61 to 70 of about 25,729 (205)
Computational investigation on the photoacoustics of malaria infected red blood cells. [PDF]
PLoS ONE, 2012 A computer simulation study on the possibility of using photoacoustic (PA) technique to differentiate intraerythrocytic stages of malarial parasite is reported. This parasite during its development substantially converts hemoglobin into hemozoin.
Ratan K Saha +2 more
doaj +1 more source
Pest Management Science, Volume 81, Issue 4, Page 2165-2180, April 2025.We used recently detected P450 DNA‐based markers of pyrethroid resistance in both Anopheles funestus and Anopheles gambiae to demonstrate that although pyrethroid‐resistant mosquitoes have higher ability to survive and live longer after exposure to Royal Guard, this net significantly affects their lifespan, blood feeding ability and interestingly ...
Emilie S Ngongang‐Yipmo +8 more
wiley +1 more source
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine
eLife, 2014 Malaria inflicts an enormous burden on global human health. The emergence of parasite resistance to front-line drugs has prompted a renewed focus on the repositioning of clinically approved drugs as potential anti-malarial therapies.
Wilson Wong +8 more
doaj +1 more source
Malarial parasites and antioxidant nutrients
Parasitology, 1993 SUMMARYSusceptibility to oxidative stress is a well-established feature of the malarial parasite. Pharmacologists have taken advantage of this property to design highly effective pro-oxidant antimalarial drugs. Less well appreciated is the fact that nutritional manipulation of host oxidative stress status by dietary means can have a profound effect on ...
O A, Levander, A L, Ager
openaire +2 more sources
Journal of Animal Ecology, EarlyView.This study proposes two contrasting scenarios for how host infectiousness is determined: recipient dependence and donor dependence. These scenarios fundamentally alter how host heterogeneity shapes parasite transmission, demonstrating that the process by which infectiousness is determined is crucial for understanding the consequences of host ...
Jacob A. Cohen +3 more
wiley +1 more source
Virulence, 2020 Malarial disease caused by Plasmodium parasites challenges the mammalian immune system with a delicate balancing act. Robust inflammatory responses are required to control parasite replication within red blood cells, which if unchecked, can lead to ...
Lisa L. Drewry, John T. Harty
doaj +1 more source
Systems analysis of chaperone networks in the malarial parasite Plasmodium falciparum. [PDF]
PLoS Computational Biology, 2007 Molecular chaperones participate in the maintenance of cellular protein homeostasis, cell growth and differentiation, signal transduction, and development. Although a vast body of information is available regarding individual chaperones, few studies have
Soundara Raghavan Pavithra +2 more
doaj +1 more source
Journal of Animal Ecology, EarlyView.In this study, the authors develop a new model to show that species contributions to parasite persistence can have strong, asynchronous temporal variability, often limiting the effectiveness of targeted seasonal parasite control. The model is broadly applicable for partitioning who, when, and what drive parasite persistence in multi‐host seasonal ...
Sarah A. R. Schrock +5 more
wiley +1 more source
Malaria Journal, 2008 Background Severe malarial anaemia is a major complication of malaria infection and is multi-factorial resulting from loss of circulating red blood cells (RBCs) from parasite replication, as well as immune-mediated mechanisms.
Lamb Tracey J, Langhorne Jean
doaj +1 more source
Quantitative bioluminescent imaging of pre-erythrocytic malaria parasite infection using luciferase-expressing Plasmodium yoelii. [PDF]
PLoS ONE, 2013 The liver stages of Plasmodium parasites are important targets for the development of anti-malarial vaccine candidates and chemoprophylaxis approaches that aim to prevent clinical infection.
Jessica L Miller +7 more
doaj +1 more source