Results 81 to 90 of about 236,694 (244)

Spillover dynamics and asynchronous temporal fluctuations in host density and competence drive fungal parasite persistence in multi‐host, seasonal communities

open access: yesJournal of Animal Ecology, EarlyView.
In this study, the authors develop a new model to show that species contributions to parasite persistence can have strong, asynchronous temporal variability, often limiting the effectiveness of targeted seasonal parasite control. The model is broadly applicable for partitioning who, when, and what drive parasite persistence in multi‐host seasonal ...
Sarah A. R. Schrock   +5 more
wiley   +1 more source

The C-terminal portion of the cleaved HT motif is necessary and sufficient to mediate export of proteins from the malaria parasite into its host cell [PDF]

open access: yes, 2013
The malaria parasite exports proteins across its plasma membrane and a surrounding parasitophorous vacuole membrane, into its host erythrocyte. Most exported proteins contain a Host Targeting motif (HT motif) that targets them for export. In the parasite
Thalassinos, Konstantinos   +4 more
core   +1 more source

REPRODUCING OPERATIONAL LANDSCAPES: The Rock Mining for Indonesia's New Capital City

open access: yesInternational Journal of Urban and Regional Research, EarlyView.
Abstract Indonesia's new capital city is designed to become a green and sustainable city. In this article, we examine the (un)sustainability of the process through which the city is coming into being. Using the sociospatial theory of planetary urbanization, we trace the dialectical relationship between the new city and sites beyond it to show how ...
Bosman Batubara   +4 more
wiley   +1 more source

Synergism of Anti-Malarial Effect of Carica papaya L. and Moringa oleifera Leaf Extracts in Mice

open access: yesMajalah Obat Tradisional
Malaria parasites, Plasmodium spp, can develop resistance to anti-malarial drugs. Hence, potential alternative therapeutic agents should be explored.
Yenni Yusuf   +9 more
doaj   +1 more source

Assessing the utility of an anti-malarial pharmacokinetic-pharmacodynamic model for aiding drug clinical development

open access: yesMalaria Journal, 2012
Background Mechanistic within-host models relating blood anti-malarial drug concentrations with the parasite-time profile help in assessing dosing schedules and partner drugs for new anti-malarial treatments.
Zaloumis Sophie   +9 more
doaj   +1 more source

Prostaglandin E2 (PGE2) signaling regulates fluid excretion and uric acid metabolism in the mosquito Anopheles gambiae

open access: yesInsect Science, EarlyView.
Prostaglandin E2 (PGE2) signaling via its receptor has integral roles in mosquito physiology, mediating fluid excretion, stimulating hindgut contractions, and in modulating uric acid levels. Together, these results uncover previously unrecognized roles of prostaglandin signaling in osmotic balance and metabolic homeostasis in mosquitoes.
Hyeogsun Kwon   +3 more
wiley   +1 more source

Laboratory Diagnosis of Malaria: Comparison of Manual and Automated Diagnostic Tests

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2017
Malaria is the second most prevalent disease in Pakistan resulting in ~30,000 annual deaths. In endemic countries like Pakistan precise and timely diagnosis of malaria is imperative to overcome the associated risks of fatal outcomes.
Samina Naz Mukry   +5 more
doaj   +1 more source

Correlation between anti-malarial and anti-haemozoin activities of anti-malarial compounds

open access: yesMalaria Journal, 2020
Background Despite noticeable improvement in anti-malarial treatment, rapid growth of resistant malaria strains points out the need for continuous development of novel anti-malarials to fight the disastrous infection.
Dao Ngoc Hien Tam   +11 more
doaj   +1 more source

THE CAUSE OF MALARIAL ANEMIA, AND THE INTRAVASCULAR MIGRATIONS OF THE MALARIAL PARASITE [PDF]

open access: yesArchives of Internal Medicine, 1912
All investigators agree that in few conditions does so marked and rapid anemia develop as in malaria. The rapidity of its development, as well as its severity, has often excited notice. For example, Dionisi1noted a reduction of 500,000 red corpuscles in twelve hours, and also demonstrated that there is no intimate relation between the number of ...
openaire   +1 more source

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