Results 81 to 90 of about 25,729 (205)

THE CAUSE OF MALARIAL ANEMIA, AND THE INTRAVASCULAR MIGRATIONS OF THE MALARIAL PARASITE [PDF]

Archives of Internal Medicine, 1912
All investigators agree that in few conditions does so marked and rapid anemia develop as in malaria. The rapidity of its development, as well as its severity, has often excited notice. For example, Dionisi1noted a reduction of 500,000 red corpuscles in twelve hours, and also demonstrated that there is no intimate relation between the number of ...
openaire   +1 more source

Domination Versus Sisterhoods in the Blood Microbiota of Migrating Birds: Patterns of Within‐ and Between‐Individual Blood Parasite Diversity Revealed Through Metabarcoding

Integrative Zoology, EarlyView.
Avian haemosporidian blood parasites are typically identified through Sanger sequencing of a partial cytochrome b fragment, the MalAvi barcoding region. Next‐generation sequencing is seldom used for avian blood parasite identification; this study demonstrates a higher detection rate of co‐infections via metabarcoding and its possible implications ...
Peter Pibaque, Gaia Porporato, Simone Cescutti, Alanis Cruz‐Flores, Tobias Busche, Anika Winker, Tim Maximilian Rapp, Patrick Bergkamp, Anna Doneva, Nayden Chakarov   +9 more
wiley   +1 more source

Urbanization and Vector Species Shape Avian Malaria Prevalence in Mosquitoes

Integrative Zoology, EarlyView.
Avian malaria prevalence was assessed in two mosquito species across urban and peri‐urban habitats. No infections were detected in either species in urban areas, while a 2.53% prevalence was found in the native Culex pipiens from peri‐urban sites, highlighting the influence of urbanization on parasite transmission dynamics.
Paula Parra, Jesús Veiga, Marta Garrigós, Guillermo Panisse, Mario Garrido, Josué Martínez‐de la Puente   +5 more
wiley   +1 more source

Severity of Vessel Color Changes and Macular and Peripheral Whitening in Malarial Retinopathy Are Associated with Higher Total Body and Sequestered Parasite Burdens

Tropical Medicine and Infectious Disease
Two-thirds of children with cerebral malaria (CM) exhibit retinopathy characterized by whitening, vessel color changes, and/or hemorrhages. The pathogenesis of malarial retinopathy is not fully understood.
Chiadika Nwanze, Daniel Muller, Priscilla Suleman, Mrinmayee Takle, John R. Barber, Kyle J. Wilson, Nicholas A. V. Beare, Karl B. Seydel, Douglas G. Postels   +8 more
doaj   +1 more source

A Global Perspective of Childhood Vaccinations: Past, Present, and Future—From Smallpox to mRNA

Acta Paediatrica, EarlyView.
ABSTRACT Childhood immunisation is one of the most successful public health interventions in history, preventing millions of deaths and substantially reducing global child mortality. This mini‐review summarises the historical development of childhood vaccines, the role of global coordination in expanding immunisation coverage, and the innovations that ...
Tobias Alfvén, Tania Reza, Alieu Sowe
wiley   +1 more source

PEG400 regulates Falcipain 2 activity through an allosteric mechanism

The FEBS Journal, EarlyView.
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath, Subhoja Chakraborty, Sampa Biswas   +2 more
wiley   +1 more source

Higher body condition with infection by Haemoproteus parasites in Bananaquits (Coereba flaveola) [PDF]

PeerJ
Parasite transmission is a heterogenous process in host-parasite interactions. This heterogeneity is particularly apparent in vector-borne parasite transmission where the vector adds an additional level of complexity.
Nicole A. Gutiérrez-Ramos, Miguel A. Acevedo   +1 more
doaj   +2 more sources

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

An automated haematology analyzer XN-30 distinguishes developmental stages of falciparum malaria parasite cultured in vitro

Malaria Journal, 2018
Background The automated haematology analyzer XN-30 (Sysmex, Kobe, Japan) easily and rapidly detects malarial parasites in clinical blood samples using flow cytometry.
Takahiro Tougan, Yuhgi Suzuki, Sawako Itagaki, Munehisa Izuka, Yuji Toya, Kinya Uchihashi, Toshihiro Horii   +6 more
doaj   +1 more source

Malaria mosquito antimicrobial defence requires immunity and detoxification gene regulation by Lola

Insect Molecular Biology, EarlyView.
Malaria mosquito antimicrobial defence requires upregulation of lola. Attenuation of lola in the midgut of Anopheles albimanus mosquitoes inhibits the upregulation of immunity genes induced by challenge. Putative target genes of the Lola transcription factor were revealed by lola attenuation, including Cecropin‐C, Draper, PPAF2, Clip‐domain serine ...
Heidi Espadas‐Álvarez, Verónica Valverde‐Garduño   +1 more
wiley   +1 more source