Results 61 to 70 of about 151,333 (388)

MoMa: An assistive mobile manipulator with a webcam-based gaze control system

HardwareX
Mobile Manipulators (MoMa) is a category of mobile robots designed to assist people with motor disabilities to perform object retrieval tasks using a webcam-based gaze control system.
James Dominic O. Go, Neal Garnett T. Ong, Carlo A. Rafanan, Brian G. Tan, Timothy Scott C. Chu   +4 more
doaj   +1 more source

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation

Advanced Science, EarlyView.
Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin, Meilian Yao, Xin Xu, Dong Zhang, Lei Xu, Ling Rong, Xiaohang Wang, Yi Duan, Chengkun Chen, Jun Gu, Yao Zhang, Qiang Liu, Qing Ye, Gaoping Cui, Yujun Hao, Xiumei Ma   +15 more
wiley   +1 more source

Chemotaxis of Bracken Spermatozoids : The Role of Bimalate Ions [PDF]

, 1958
1. Bracken spermatozoids are chemotactically attracted by malic acid salts and in a pH gradient aggregate between pH 3.5 and 5.6. 2. This response to pH occurs only when the sperm suspension contains malate. 3. At higher pH's, the response to an H+
Brokaw, C. J.
core   +1 more source

Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells. [PDF]

, 2017
Metformin is a widely used agent for the treatment of diabetes and infertility, however, it has been found to have anti-cancer effects in a variety of malignancies including high grade serous ovarian cancer (HGSC).
Aspuria, Paul-Joseph P, Hodeib, Melissa, Karlan, Beth Y, Lunt, Sophia Y, Ogrodzinski, Martin P, Reue, Karen, Vergnes, Laurent   +6 more
core   +1 more source

Molecular Simulations of Unexplored Philippine Plant Constituents on the Inhibition of the Proinflammatory Marker NF-κB p50 Subunit

Crystals
Inflammation serves as a pivotal defense mechanism orchestrated by the innate immune system to safeguard cellular health against adversities. Nonetheless, dysregulated inflammatory responses can precipitate chronic inflammatory ailments, notably ...
Jasmine U. Ting, Maria Carmen S. Tan, Vincent Antonio S. Ng, Stephani Joy Y. Macalino, Virgilio C. Linis, Glenn G. Oyong   +5 more
doaj   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Chemical genetics uncovers novel inhibitors of lignification, including p-iodobenzoic acid targeting CINNAMATE-4-HYDROXYLASE [PDF]

, 2016
Plant secondary-thickened cell walls are characterized by the presence of lignin, a recalcitrant and hydrophobic polymer that provides mechanical strength and ensures long-distance water transport.
Audenaert, Dominique, Boerjan, Wout, Decou, Raphael, Goeminne, Geert, Höfer, René, Nguyen, Long, Pesquet, Edouard, Van de Wouwer, Dorien, Vanholme, Bartel, Vanholme, Ruben   +9 more
core   +2 more sources

Streamlining extracellular polymeric substance removal: Fuzzy multi-objective optimization of ultrasonic-Fenton treatment

Resources, Environment and Sustainability
Managing high water content sludge in wastewater treatment is crucial for sustainability. This involves a complex challenge of maximizing the removal of loosely bound extracellular polymeric substances (LB-EPS) while minimizing ultrasonic-Fenton process ...
Angelo Earvin Sy Choi, Danielle Grace Evangelista, Joseph R. Ortenero   +2 more
doaj   +1 more source

First quantitative assessment of growth, sugar accumulation and malate breakdown in a single ripening berry

OENO One, 2020
Background: Most approaches to grape physiology accept that the berry and the future harvest should display identical developmental features, which obviously requires synchronised fruits. Aims: Rejecting this assumption compels to revisit the kinetic and
Rezk Shahood, Laurent Torregrosa, Stefania Savoi, Charles Romieu   +3 more
doaj   +1 more source

Mitochondrial CISD1 Modulates Microglial Metabolic Reprogramming to Drive Stress Susceptibility in Mice

Advanced Science, EarlyView.
CDGSH iron sulfur domain 1 (CISD1) mitigates oxidative stress by promoting NADH oxidation and Coenzyme Q (CoQ) reduction. Under chronic stress, elevated CISD1 expression in microglia enhances NAD⁺ production, thereby increasing GAPDH activity and glycolytic flux, while reducing ATP synthesis by inhibiting proton transfer from mitochondrial complexes I ...
Wanting Dong, Duo Liu, Songsen Fu, Jiaming Zhang, Xi Chen, Songqiang Huang   +5 more
wiley   +1 more source