Results 1 to 10 of about 37,753 (202)

Malic Enzyme, not Malate Dehydrogenase, Mainly Oxidizes Malate That Originates from the Tricarboxylic Acid Cycle in Cyanobacteria [PDF]

open access: yesmBio, 2022
Oxygenic photoautotrophic bacteria, cyanobacteria, have the tricarboxylic acid (TCA) cycle, and metabolite production using the cyanobacterial TCA cycle has been spotlighted recently. The unicellular cyanobacterium Synechocystis sp.
Noriaki Katayama   +4 more
doaj   +2 more sources

Malate dehydrogenase 2 deficiency is an emerging cause of pediatric epileptic encephalopathy with a recognizable biochemical signature [PDF]

open access: yesMolecular Genetics and Metabolism Reports, 2022
Malate dehydrogenases (MDH) serve a critical role in maintaining equilibrium of the NAD+/NADH ratio between the mitochondria and cytosol through the catalysis of the oxidation of L-malate to oxaloacetate in a reversible, NADH-dependent manner.
Jessica R.C. Priestley   +18 more
doaj   +2 more sources

Plasmodium Parasite Malate-Quinone Oxidoreductase Functionally Complements a Yeast Deletion Mutant of Mitochondrial Malate Dehydrogenase [PDF]

open access: yesMicrobiology Spectrum, 2023
The emergence of drug-resistant variants of malaria-causing Plasmodium parasites is a life-threatening problem worldwide. Investigation of the physiological function of individual parasite proteins is a prerequisite for a deeper understanding of the ...
Takeshi Ito   +3 more
doaj   +2 more sources

A Redox-Neutral, Two-Enzyme Cascade for the Production of Malate and Gluconate from Pyruvate and Glucose

open access: yesApplied Sciences, 2021
A triple mutant of NADP(H)-dependent malate dehydrogenase from thermotolerant Thermococcus kodakarensis has an altered cofactor preference for NAD+, as well as improved malate production compared to wildtype malate dehydrogenase.
Ravneet Mandair   +2 more
doaj   +1 more source

NON-COENZYME PROPERTIES OF THIAMINE: EVALUATION OF BINDING AFFINITY TO MALATE DEHYDROGENASE ISOFORMS [PDF]

open access: yesBiotechnologia Acta, 2020
The aim of this work was evaluation of binding affinity of thiamine to malate dehydrogenase isoforms. The methods of affinity chromatography, SDS PAGE electrophoresis, and MALDI-TOF mass spectroscopy, as well as molecular modeling in silico were used in ...
O. Mezhenska   +5 more
doaj   +1 more source

Photoelectrochemical Enzyme Biosensor for Malate Using Quantum Dots on Indium Tin Oxide/Plastics as a Sensing Surface

open access: yesBiosensors, 2023
A photoelectrochemical biosensor for malate was developed using an indium tin oxide (ITO) layer deposited on a poly(ethylene terephthalate) plastic sheet as a transparent electrode material for the immobilization of malate dehydrogenase together with ...
Tereza Hlaváčová, Petr Skládal
doaj   +1 more source

Dehydrogenaze polymorphism as a tool for early selection of low vigour rootstock for sweet and sour cherry [PDF]

open access: yesJournal of Agricultural Sciences (Belgrade), 2017
The correlation of dehydrogenase isoenzyme profile with plant/tree vigour of twenty genotypes belonging to the genus Prunus and the subgenus Cerasus as well as to four commercial rootstocks (Colt, Gisela 5, Gisela 6 and MaxMa 14) was ...
Čolić Slavica D.   +3 more
doaj   +1 more source

Seasonal changes in blood serum of trout females Salmo trutta L [PDF]

open access: yesActa Ichthyologica et Piscatoria, 1972
The lipids, total and non-esterified cholesterol, total protein and the activity of malate-dehydrogenase (MDH) were determined in blood serum of trout females with gonads of III stage maturity, according to Mayer's scale, and during spawning period.
C. Felińska
doaj   +3 more sources

Malate and fumarate extend lifespan in Caenorhabditis elegans. [PDF]

open access: yesPLoS ONE, 2013
Malate, the tricarboxylic acid (TCA) cycle metabolite, increased lifespan and thermotolerance in the nematode C. elegans. Malate can be synthesized from fumarate by the enzyme fumarase and further oxidized to oxaloacetate by malate dehydrogenase with the
Clare B Edwards   +4 more
doaj   +1 more source

Biochemical adaptation of Weigela florida «Variegata» Bunge A. D. C. microclones to salt- and copper induced stress [PDF]

open access: yesСибирский лесной журнал, 2017
Microclones of perennial shrub Weigela florida «Variegata» were prepared, adapted to the conditions of salinity and increased copper ions proportion during the three-step in vitro experiment.
O. A. Zemlyanukhina   +3 more
doaj   +1 more source

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