Malic Enzyme, not Malate Dehydrogenase, Mainly Oxidizes Malate That Originates from the Tricarboxylic Acid Cycle in Cyanobacteria [PDF]
mBio, 2022 Oxygenic photoautotrophic bacteria, cyanobacteria, have the tricarboxylic acid (TCA) cycle, and metabolite production using the cyanobacterial TCA cycle has been spotlighted recently. The unicellular cyanobacterium Synechocystis sp.
Noriaki Katayama +4 more
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Malate dehydrogenase 2 deficiency is an emerging cause of pediatric epileptic encephalopathy with a recognizable biochemical signature [PDF]
Molecular Genetics and Metabolism Reports, 2022 Malate dehydrogenases (MDH) serve a critical role in maintaining equilibrium of the NAD+/NADH ratio between the mitochondria and cytosol through the catalysis of the oxidation of L-malate to oxaloacetate in a reversible, NADH-dependent manner.
Jessica R.C. Priestley +18 more
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Plasmodium Parasite Malate-Quinone Oxidoreductase Functionally Complements a Yeast Deletion Mutant of Mitochondrial Malate Dehydrogenase [PDF]
Microbiology Spectrum, 2023 The emergence of drug-resistant variants of malaria-causing Plasmodium parasites is a life-threatening problem worldwide. Investigation of the physiological function of individual parasite proteins is a prerequisite for a deeper understanding of the ...
Takeshi Ito +3 more
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The intracellular localization of malate dehydrogenase isoenzymes in Pisum arvense roots
Acta Societatis Botanicorum Poloniae, 2014 Mitochondria and plastids were isolated from Pisum arvense root cells by sucrose density gradient centrifugation. The individual subcellular fractions so obtained were subjected to isoelectric focusing on cellulose acetate strips.
Genowefa Kubik-Dorosz
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CHANGES IN SERUM ENZYMES LEVELS ASSOCIATED WITH LIVER FUNCTIONS IN STRESSED MARWARI GOAT [PDF]
Journal of Stress Physiology & Biochemistry, 2011 Serum enzyme levels were determined in goats of Marwari breed belonging to farmers’ stock of arid tract of Rajasthan state, India. The animals were grouped into healthy and stressed comprising of gastrointestinal parasiticised, pneumonia affected, and ...
Kataria N. +3 more
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Induced pluripotent stem cell-derived hepatocytes reveal TCA cycle disruption and the potential basis for triheptanoin treatment for malate dehydrogenase 2 deficiency [PDF]
Molecular Genetics and Metabolism ReportsMitochondrial malate dehydrogenase 2 (MDH2) is crucial to cellular energy generation through direct participation in the tricarboxylic acid (TCA) cycle and the malate aspartate shuttle (MAS).
Déborah Mathis +8 more
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Is the TCA cycle malate dehydrogenase-citrate synthase metabolon an illusion? [PDF]
Essays BiochemOmini J +4 more
europepmc +3 more sources
Applied Sciences, 2021 A triple mutant of NADP(H)-dependent malate dehydrogenase from thermotolerant Thermococcus kodakarensis has an altered cofactor preference for NAD+, as well as improved malate production compared to wildtype malate dehydrogenase.
Ravneet Mandair +2 more
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Redox regulation of NADP-malate dehydrogenase is vital for land plants under fluctuating light environment. [PDF]
Proc Natl Acad Sci U S A, 2021 Yokochi Y +7 more
europepmc +3 more sources