Gain of interaction of ALS-linked G93A superoxide dismutase with cytosolic malate dehydrogenase
Neurobiology of Disease, 2008 Protein interactions of the Amyotrophic Lateral Sclerosis (ALS)-linked copper–zinc superoxide dismutase (hSOD1) G93A mutation were studied using a fluorescence resonance energy transfer (FRET) based screening system.
Yael Mali, Nava Zisapels
doaj +1 more source
Diagnostic Alleles From Electrophoresis Distinguish Two Noctuid Pest Species, \u3ci\u3eHydraecia Immanis\u3c/i\u3e and \u3ci\u3eH. Micacea\u3c/i\u3e (Lepidoptera: Noctuidae). [PDF]
, 2017 Native hop vine borer (Hydraecia immanis) and introduced potato stem borer (H. micacea) populations in Midwest corn have reached noticeable levels near the Great Lakes plant community ecotone between boreal forests and temperate deciduous forests.
Bossart, Janice L +2 more
core +2 more sources
An experimental point of view on hydration/solvation in halophilic proteins
Frontiers in Microbiology, 2014 Protein-solvent interactions govern the behaviour of proteins isolated from extreme halophiles. In this work, we compared the solvent envelopes of two orthologous tetrameric malate dehydrogenases from halophilic and non-halophilic bacteria.
Romain eTalon +11 more
doaj +1 more source
CELLULOSE ACETATE ELECTROPHORESIS OF MALATE DEHYDROGENASE
THE JOURNAL OF VITAMINOLOGY, 1964 1. Heterogeneity of malate dehydrogenase (MDH) activities was proved by electrophoresis on cellulose acetate of rat and human tissue homogenates. Two or more separable forms of MDH activities were found in these tissues. Each tissue exhibited a similar distribution of MDH activities.2.
Shunji Sawaki, Noriyuki Morikawa
openaire +4 more sources
Multistationary and Oscillatory Modes of Free Radicals Generation by the Mitochondrial Respiratory Chain Revealed by a Bifurcation Analysis [PDF]
, 2012 The mitochondrial electron transport chain transforms energy satisfying cellular demand and generates reactive oxygen species (ROS) that act as metabolic signals or destructive factors.
Mark F. Schumaker +6 more
core +5 more sources
Interdisciplinary Medicine, EarlyView.Although most cancer cells rely on aerobic glycolysis, Oxidative phosphorylation (OXPHOS) remains essential for their survival, proliferation, and metastasis. With the emergence of OXPHOS‐targeted drugs, its therapeutic potential is becoming increasingly evident.
Keke Chen +5 more
wiley +1 more source
Malate dehydrogenase activity in human seminal plasma and spermatozoa homogenates
Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2013 Purpose: Malate Dehydrogenase is an important enzyme of the Krebs cycle, most cells require this enzyme for their metabolic activity. We evaluated the Malate Dehydrogenase (NAD/NADP) activity in human seminal plasma and sperm homogenates in ...
Hulya Leventerler +6 more
doaj
Cell Research, 2018 Programmed cell death (PCD) is a fundamental biological process. Deficiency in MOSAIC DEATH 1 (MOD1), a plastid-localized enoyl-ACP reductase, leads to the accumulation of reactive oxygen species (ROS) and PCD, which can be suppressed by mitochondrial ...
Yannan Zhao +12 more
semanticscholar +1 more source
Insight into the Carboxyl Transferase Domain Mechanism of Pyruvate Carboxylase from \u3cem\u3eRhizobium etli\u3c/em\u3e [PDF]
, 2009 The effects of mutations in the active site of the carboxyl transferase domain of Rhizobium etli pyruvate carboxylase have been determined for the forward reaction to form oxaloacetate, the reverse reaction to form MgATP, the oxamate-induced ...
Attwood, Paul V +5 more
core +1 more source
Synergistic interaction of fatty acids and oxysterols impairs mitochondrial function and limits liver adaptation during nafld progression [PDF]
, 2018 The complete mechanism accounting for the progression from simple steatosis to steatohepatitis in nonalcoholic fatty liver disease (NAFLD) has not been elucidated.
Avolio, Carlo +11 more
core +2 more sources