Determination of Metabolite Interactions to Malate Dehydrogenase by Fluorescence Spectroscopy
, 2023 Aqeel Rana Afzal, Che‐Hun Jung
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The Journal of Physiology, EarlyView.Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma +12 more
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Mitochondrial physiology in cardiac muscle of deer mice native to high altitude
The Journal of Physiology, EarlyView.Abstract figure legend High‐altitude deer mice exhibited evolved changes in mitochondrial energy metabolism and reactive oxygen species (ROS) management that may support cardiac performance under cold hypoxic conditions. High‐altitude mice had increased activity of lactate dehydrogenase (LDH) in the heart, probably enhancing the capacity for lactate ...
Ranim Saleem +3 more
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Increasing access for biochemistry research in undergraduate education: The malate dehydrogenase CURE community. [PDF]
J Biol Chem, 2022 Provost JJ.
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The structures ofapo- andholo-cytoplasmic malate dehydrogenase at high resolution [PDF]
, 1981 Jens J. Birktoft +2 more
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Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.This work presents the physiological exploration of the halo‐alkaliphilic, carboxydotrophic acetogen bacterium MD4. In contrast to well‐characterised neutrophilic and slightly acidophilic acetogenic carboxydotrophs, this work shows an important role for formate production, instead of ethanol, as a redox exhaust mechanism in alkaline conditions ...
Martijn Diender +5 more
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Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells [PDF]
, 2022 Patricia Altea‐Manzano +15 more
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Lifespan‐Extending Endogenous Metabolites
Aging Cell, Volume 25, Issue 2, February 2026.Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
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Mitochondrial fatty acid oxidation is stimulated by red light irradiation
FEBS Letters, Volume 600, Issue 1, Page 20-38, January 2026.Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera +4 more
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Inhibition of Malate Dehydrogenase-2 Protects Renal Tubular Epithelial Cells from Anoxia-Reoxygenation-Induced Death or Senescence. [PDF]
Biomolecules, 2022 Eleftheriadis T +5 more
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