Results 21 to 30 of about 369,142 (349)

Malate Dehydrogenase, Mitochondrial

open access: yesDefinitions, 2020
Malate dehydrogenase, mitochondrial (338 aa, ~36 kDa) is encoded by the human MDH2 gene. This protein plays a role in the conversion of malate to oxaloacetate.

semanticscholar   +1 more source

Biochemical adaptation of Weigela florida «Variegata» Bunge A. D. C. microclones to salt- and copper induced stress [PDF]

open access: yesСибирский лесной журнал, 2017
Microclones of perennial shrub Weigela florida «Variegata» were prepared, adapted to the conditions of salinity and increased copper ions proportion during the three-step in vitro experiment.
O. A. Zemlyanukhina   +3 more
doaj   +1 more source

Effects of caloric restriction and ketogenic diet on renal fibrosis after ischemia/reperfusion injury

open access: yesHeliyon, 2023
The beneficial effects of caloric restriction (CR) and a ketogenic diet (KD) have been previously shown when performed prior to kidney injury. We investigated the effects of CR and KD on fibrosis development after unilateral kidney ischemia/reperfusion ...
E.I. Yakupova   +11 more
doaj   +1 more source

Disruption of the MreB Elongasome Is Overcome by Mutations in the Tricarboxylic Acid Cycle

open access: yesFrontiers in Microbiology, 2021
The bacterial actin homolog, MreB, is highly conserved among rod-shaped bacteria and essential for growth under normal growth conditions. MreB directs the localization of cell wall synthesis and loss of MreB results in round cells and death.
Brody Barton   +2 more
doaj   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

open access: yesHepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario   +12 more
wiley   +1 more source

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

open access: yesHepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro   +14 more
wiley   +1 more source

The photoinhibition of malate dehydrogenase [PDF]

open access: yesFEBS Letters, 1972
Recently several enzymes which require FMN as a cofactor have been shown to be inhibited by blue light in the presence of added FMN [l-3] . Photoinactivation of the enzyme protein occurred via the formation of triplet FMN. The present paper reports, for the first time, an FMN-mediated photoinhibition of NAD-malate dehydrogenase, a key enzyme of the ...
openaire   +3 more sources

Molecular mechanisms of the non-coenzyme action of thiamin in brain. Biochemical, structural and pathway analysis [PDF]

open access: yes, 2015
Thiamin (vitamin B1) is a pharmacological agent boosting central metabolism through the action of the coenzyme thiamin diphosphate (ThDP). However, positive effects, including improved cognition, of high thiamin doses in neurodegeneration may be ...
Andrey, Vovk   +9 more
core   +1 more source

LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]

open access: yes, 2014
The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart   +7 more
core   +2 more sources

Enzymatic determination of bile acids from liver cells with 3 alpha-hydroxysteroid dehydrogenase--a warning.

open access: yesJournal of Lipid Research, 1981
3 alpha-Hydroxysteroid dehydrogenase was used to monitor bile acid production by rat hepatocyte suspensions. Several observations suggested that the method lacked specificity and detected some other metabolites besides bile acids.
C A Barth, K Wirthensohn
doaj   +1 more source

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