Results 41 to 50 of about 74,420 (312)

Magnesium deficiency-induced changes in organic acid metabolism of Citrus sinensis roots and leaves

Biologia Plantarum, 2013
Organic acid (OA) metabolisms are of fundamental importance but very limited data are available on the responses of plant OA metabolisms to Mg-deficiency. Seedlings of Citrus sinensis (L.) Osbeck cv. Xuegan were irrigated with Mg-deficient (0, 50, or 500
L.T. Yang, G.H. Yang, X. You, C.P. Zhou, Y.B. Lu, L.S. Chen   +5 more
doaj   +1 more source

Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death. [PDF]

, 2017
Glutamate is the dominant excitatory neurotransmitter in the brain, but under conditions of metabolic stress it can accumulate to excitotoxic levels.
Andreyev, Alexander Y, Bloodgood, Brenda L, Buren, Caodu, Cordes, Thekla, Divakaruni, Ajit S, Fields, Jerel A, Li, Edward, Martyniuk, Kelly, Metallo, Christian M, Murphy, Anne N, Raymond, Lynn A, Reynolds, Ian J, Wallace, Martina   +12 more
core   +1 more source

ACTIVITY OF DEHYDROGENASES IN THE PROCESS OF TIMPANY DEVELOPMENT IN YOUNG STURGEON OF ACIPENSER RUTHENUS L

Юг России: экология, развитие, 2014
When young sterlet is suffering from tympanism, biochemical and pathophysiological disorders are observed; the activity of malate dehydrogenase and succinate dehydrogenase lowers in the fish liver and muscles, while the activity of lactate dehydrogenase ...
N. A. Abrosimova, K. S. Abrosimova
doaj   +1 more source

Complete genome sequence of Syntrophobacter fumaroxidans strain (MPOB(T)). [PDF]

, 2012
Syntrophobacter fumaroxidans strain MPOB(T) is the best-studied species of the genus Syntrophobacter. The species is of interest because of its anaerobic syntrophic lifestyle, its involvement in the conversion of propionate to acetate, H2 and CO2 during ...
Crable, Bryan R, Goltsman, Eugene, Gunsalus, Robert P, Henstra, Anne M, Kim, Edwin, Lapidus, Alla L, Lykidis, Athanasios, McDonald, Erin, McInerney, Michael J, Paulitsch-Fuchs, Astrid H, Plugge, Caroline M, Rohlin, Lars, Scholten, Johannes CM, Stams, Alfons JM, Swarts, Daan C, Worm, Petra   +15 more
core   +2 more sources

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Succinate Can Shuttle Reducing Power from the Hypoxic Retina to the O2-Rich Pigment Epithelium

Cell Reports, 2020
Summary: When O2 is plentiful, the mitochondrial electron transport chain uses it as a terminal electron acceptor. However, the mammalian retina thrives in a hypoxic niche in the eye.
Celia M. Bisbach, Daniel T. Hass, Brian M. Robbings, Austin M. Rountree, Martin Sadilek, Ian R. Sweet, James B. Hurley   +6 more
doaj   +1 more source

Mitochondrial CISD1 Modulates Microglial Metabolic Reprogramming to Drive Stress Susceptibility in Mice

Advanced Science, EarlyView.
CDGSH iron sulfur domain 1 (CISD1) mitigates oxidative stress by promoting NADH oxidation and Coenzyme Q (CoQ) reduction. Under chronic stress, elevated CISD1 expression in microglia enhances NAD⁺ production, thereby increasing GAPDH activity and glycolytic flux, while reducing ATP synthesis by inhibiting proton transfer from mitochondrial complexes I ...
Wanting Dong, Duo Liu, Songsen Fu, Jiaming Zhang, Xi Chen, Songqiang Huang   +5 more
wiley   +1 more source

Reproductive strategies and genetic variability in tropical freshwater fish

Genetics and Molecular Biology, 2007
We estimated the genetic variability of nine fish species from the Brazilian upper Paraná River floodplain (Astyanax altiparanae, Hoplias malabaricus, Leporinus lacustris, Loricariichthys platymetopon, Parauchenipterus galeatus, Pimelodus maculatus ...
Maria Dolores Peres Lassala, Erasmo Renesto   +1 more
doaj   +1 more source

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

Advanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou, Junxian Chen, Hongxia Zhang, Lu Guo, Kevin Mai, Elijah Abraham, Dilip V. Prajapati, Yue Chang, Jing Ning, Xinchen Wang, Defeng Li, Dan‐Dan Zhang, Jianghua Sun, Rebecca A. Butcher, Lilin Zhao   +14 more
wiley   +1 more source

The Neuroprotective Effects of Curcumin Nanoparticles on The Cerebral Ischemia-Reperfusion Injury in The Rats-The Roles of The Protein Kinase RNA-Like ER Kinase/Extracellular Signal-Regulated Kinase and Transcription Factor EB proteins [PDF]

Cell Journal
Objective: Reduction of cerebral ischemia-reperfusion injury (IRI)/re-oxygenation injury, is defined as the paradoxicalexacerbation of the cellular dysfunction and death, following restoration of the blood flow to previously ischemic tissues.The re ...
Yalda Saghari, Monireh Movahedi, Majid Tebianian, Maliheh Entezari   +3 more
doaj   +1 more source