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Applications of MALDI-TOF MS in environmental microbiology.
The Analyst, 2016Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) is an emerging technique for microbial identification, characterization, and typing.
Inês C. Santos +2 more
semanticscholar +3 more sources
SERS and MALDI-TOF MS based plasma exosome profiling for rapid detection of osteosarcoma.
In Analysis, 2021Osteosarcoma is the most frequent primary bone cancer, particularly among children and adolescents. The early diagnosis of osteosarcoma is significant for timely clinical treatment to reduce the mortality of patients.
Zhenzhen Han +9 more
semanticscholar +1 more source
Frontiers in Bioscience, 2007
So far, matrix-assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI-TOF MS) seemed to be nearly a synonym for protein analysis. However, there is growing evidence that this technique is also an useful tool in lipid analysis and lipidomics because of its fast, simple and convenient performance allowing to record mass spectra ...
Jurgen, Schiller +5 more
openaire +2 more sources
So far, matrix-assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI-TOF MS) seemed to be nearly a synonym for protein analysis. However, there is growing evidence that this technique is also an useful tool in lipid analysis and lipidomics because of its fast, simple and convenient performance allowing to record mass spectra ...
Jurgen, Schiller +5 more
openaire +2 more sources
Wine yeast typing by MALDI-TOF MS
Applied Microbiology and Biotechnology, 2014For the production of wine, the most important industrially used yeast species is Saccharomyces cerevisiae. Years of experience have shown that wine quality and property are significantly affected by the employed strain conducting the fermentation. Consequently, the ability of a strain level differentiation became an important requirement of modern ...
Usbeck, J.C. +4 more
openaire +3 more sources
Analysis of Microarrays by MALDI‐TOF MS
Angewandte Chemie International Edition, 2013Ligand libraries can be printed onto a sandwich composed of activated lipids embedded in a hydrophobic layer conjugated to an indium-tin oxide (ITO) surface. Arrays produced this way can be analyzed by fluorescence spectroscopy and mass spectrometry.
Ana, Beloqui +6 more
openaire +2 more sources
Biomarker Characterization by MALDI–TOF/MS
2015Mass spectrometric techniques frequently used in clinical diagnosis, such as gas chromatography-mass spectrometry, liquid chromatography-mass spectrometry, ambient ionization mass spectrometry, and matrix-assisted laser desorption ionization/time-of-flight mass spectrometry (MALDI-TOF/MS), are discussed.
Yi-Tzu, Cho +6 more
openaire +2 more sources
Methods, 2016
The increasing number of bioconjugates used for bioanalytical purposes and in pharmaceutical industries has led to an increasing demand for robust quality control of products derived from covalently linking small molecules to proteins. Here we report, for the first time, a matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF)-based ...
Martina Marchetti-Deschmann +5 more
openaire +2 more sources
The increasing number of bioconjugates used for bioanalytical purposes and in pharmaceutical industries has led to an increasing demand for robust quality control of products derived from covalently linking small molecules to proteins. Here we report, for the first time, a matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF)-based ...
Martina Marchetti-Deschmann +5 more
openaire +2 more sources
An update on the routine application of MALDI-TOF MS in clinical microbiology
Espert Review of Proteomics, 2019Introduction: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has entered clinical diagnostics and is today a generally accepted and integral part of the workflow for microbial identification.
M. Welker +4 more
semanticscholar +1 more source
Challenges in biomarker discovery with MALDI-TOF MS
Clinica Chimica Acta, 2016MALDI-TOF MS technique is commonly used in system biology and clinical studies to search for new potential markers associated with pathological conditions. Despite numerous concerns regarding a sample preparation or processing of complex data, this strategy is still recognized as a popular tool and its awareness has risen in the proteomic community ...
Joanna, Hajduk +2 more
openaire +2 more sources
Identification of flea species using MALDI-TOF/MS
Comparative Immunology, Microbiology and Infectious Diseases, 2014In the present study, a molecular proteomics (MALDI-TOF/MS) approach was used as a tool for identifying flea vectors. We measured the MS spectra from 38 flea specimens of 5 species including Ctenocephalides felis, Ctenocephalides canis, Archaeopsylla erinacei, Xenopsylla cheopis and Stenoponia tripectinata. A blind test performed with 24 specimens from
Amina, Yssouf +8 more
openaire +2 more sources