Results 71 to 80 of about 197,934 (334)

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Identification of dermatophytes by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry [PDF]

, 2017
In this study we evaluated the suitability of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for the identification of dermatophytes in diagnostic laboratories.
Bosshard, Philipp P., de Respinis, Sophie, Petrini, Liliane, Petrini, Orlando, Pranghofer, Sigrid, Tonolla, Mauro   +5 more
core  

MALDI-TOF MS in the Microbiology Laboratory: Current Trends.

Current Issues in Molecular Biology, 2017
Within less than a decade matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has become a gold standard for microbial identification in clinical microbiology laboratories.
S. Schubert, M. Kostrzewa
semanticscholar   +1 more source

Identification of Photorhabdus symbionts by MALDI-TOF MS

Microbiology, 2020
Species of the bacterial genus Photorhabus live in a symbiotic relationship with Heterorhabditis entomopathogenic nematodes. Besides their use as biological control agents against agricultural pests, some
Virginia Hill, Peter Kuhnert, Matthias Erb, Ricardo A. R. Machado   +3 more
openaire   +2 more sources

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

Advanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins, Samuel L. Hallam, Mariah J. Austin, Adrianne M. Rosales   +3 more
wiley   +1 more source

Identification Of Endophytic Bacteria From Curcuma Zedoaria Based On Protein Profile Using Maldi-tof Mass Spectrometry [PDF]

, 2018
Valid identification of microorganisms is a vital information to establish culture collections. Currently, molecular approach based on 16S rDNA is widely used for bacterial identification. This approach is however, time consuming and expensive.
Lisdiyanti, P. (Puspita), Sulistiyani, T. R. (Tri)   +1 more
core  

Structure analysis of biologically important prokaryotic glycopolymers [PDF]

, 2013
Of the many post-translational modifications organisms can undertake, glycosylation is the most prevalent and the most diverse. The research in this thesis focuses on the structural characterisation of glycosylation in two classes of glycopolymer (
Ventura, Valeria Victoria, Ventura, Valeria Victoria   +1 more
core   +1 more source

Investigating the Quantitative Nature of MALDI-TOF MS [PDF]

Molecular & Cellular Proteomics, 2008
MALDI-TOF MS has been applied by several groups to relative quantitative measurements. At the same time, the non-quantitative character of this method has been widely reported. We conducted experiments to test the reliability of this technique for quantitation using the statistical method of inverse confidence limit calculation for the first time in ...
Emília, Szájli, Tamás, Fehér, Katalin F, Medzihradszky   +2 more
openaire   +2 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

New insights for diagnosis of Pineapple Fusariosis by MALDI-TOF MS technique [PDF]

, 2016
Fusarium is one of the most economically important fungal genus, since it includes many pathogenic species which cause a wide range of plant diseases. Morphological or molecular biology identification of Fusarium species is a limiting step in the fast ...
A Nicolau, C Marinach-Patrice, C Santos, C Santos, C Santos, Cledir Santos, DM Geiser, F Ahmad, FC Silva, H Dong, H Dong, HN Shah, J Kemptner, J Kemptner, JF Leslie, José Aires Ventura, K O’Donnell, L Ferreira, L Pereira, LF Marvin, M Marchetti-Deschmann, MH Sedra, MME Oliveira, MRZ Passarini, N Dias, Nelson Lima, P Rodrigues, S Respinis De, V Rahjoo   +28 more
core   +1 more source