Results 251 to 260 of about 167,858 (299)

MALDI-2 and t-MALDI-2 Mass Spectrometry Imaging

2021
Matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI) combined with laser-induced postionization for MALDI-2 enables the simultaneous registration of numerous classes of small molecules (e.g., secondary metabolites including sterols) as well as phospholipids, glycolipids, and glycans from tissue sections and from cell ...
Klaus, Dreisewerd, Tanja, Bien, Jens, Soltwisch   +2 more
openaire   +2 more sources

MALDI MS

2009
Matrix-assisted laser desorption/ionization (MALDI) is a key technique in mass spectrometry (MS)-based proteomics. MALDI MS is extremely sensitive, easy-to-apply, and relatively tolerant to contaminants. Its high-speed data acquisition and large-scale, off-line sample preparation has made it once again the focus for high-throughput proteomic analyses ...
openaire   +2 more sources

The Desorption Process in MALDI

Chemical Reviews, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +2 more sources

Tissue MALDI Mass Spectrometry Imaging (MALDI MSI) of Peptides

2015
Matrix assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) is a technique to visualize molecular features of tissues based on mass detection. This chapter focuses on MALDI MSI of peptides and provides detailed operational instructions for sample preparation of cryoconserved and formalin-fixed paraffin-embedded (FFPE) tissue ...
Birte, Beine, Hanna C, Diehl, Helmut E, Meyer, Corinna, Henkel   +3 more
openaire   +2 more sources

Matrix-Assisted Laser Desorption Ionization (MALDI) and Atmospheric Pressure-MALDI (AP-MALDI)

2020
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry is one of the most widely used soft ionization methods for biomolecules. Atmospheric pressure-MALDI was introduced, increasing the ease of sample preparation and allowing for the analysis of volatile molecules, as the sample no longer needs to be placed under vacuum prior to analysis.
openaire   +1 more source

MALDI

Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry (MALDI-IMS) is a label-free technique that generates spatially resolved molecular maps of lipids, metabolites, peptides, and proteins directly from intact tissue sections. A UV-absorbing matrix is applied to the tissue surface; a pulsed laser co-desorbs and ionizes analyte molecules ...
Fisher, Stephen A, Hardi, Josef, Morgan, Richard, Musen, Mark A, Silverstein, Jonathan C, Nordgren, Erik, Kant, Peter M, Honick, Brendan John, O'Connor, Martin J, Rosario, Jean G, Gehlenborg, Nils, Blood, Philip D, Ahn, Kyung Jin, Anderton, Christopher R, Bandyopadhyay, Shovik, Bedi, Kenneth C, Brusko, Maigan, Campbell-Thompson, Martha, Carson, James, Carver, Chase M, Chen, Jing, Corbett, Anthony M, Cuaycal, Alexandra E, Cuda, Penny, Diep, Dinh, Domanskyi, Sergii, Donahue, Sean, Duffy, Michael P, Eadon, Michael T, Fan, Jean, Farrow, Melissa A, Fisch, Kathleen M, Flynn, William F, Fulcher, James M, Ghose, Soumya, Ginty, Fiona, Gonçalves, Joana P, He, Yongqun, Hu, Po, Jain, Sanjay, Karathanos, Thomas V, Kaushal, Madhurima, Kruse, Angela RS, Kwon, Yumi, Lake, Blue B, Lardenoije, Roy, Lin, Shin, Lin, Yiing, Lindsay, Scott A, Lu, Peiran, Mathews, Clayton, McDonough, Elizabeth, Melo Ferreira, Ricardo, Monte, Emma M, O'Neill, Kathleen, Pang, Minxing, Parast, Mana, Pei, Liming, Peters, Samuel, Pillai, Ajay, Pryhuber, Gloria, Qin, Ling, Rajbhandari, Presha, Ruffalo, Matthew M, Sarder, Pinaki, Saunders, Diane C, Schneider, Kevin, Shi, Lingyan, Sivajothi, Santhosh, Smith, David, Spraggins, Jeff M, Stanley, Valentina, Tan, Kai, Thadi, Anusha, Tian, Hua, Turner, Morgan L, Vlachos, Ioannis S, Winfree, Seth, Wu, Pei-Hsun, Zemaitis, Kevin J, Zhou, Mowei, Zhu, Chenchen   +81 more
openaire   +1 more source

MALDI, AP/MALDI and ESI techniques for the MS detection of amyloid β-peptides

International Journal of Mass Spectrometry, 2009
Abstract Amyloid β-peptides (Aβs) are involved in several neuropathological conditions such as Alzheimer's disease and considerable experimental evidences have emerged indicating that different proteases play a major role in regulating the accumulation of Aβs in the brain.
GRASSO, GIUSEPPE, MINEO, PLACIDO, RIZZARELLI, Enrico, SPOTO, Giuseppe   +3 more
openaire   +3 more sources

MALDI-TOF MS in lipidomics

Frontiers in Bioscience, 2007
So far, matrix-assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI-TOF MS) seemed to be nearly a synonym for protein analysis. However, there is growing evidence that this technique is also an useful tool in lipid analysis and lipidomics because of its fast, simple and convenient performance allowing to record mass spectra ...
Jurgen, Schiller, Rosmarie, Suss, Beate, Fuchs, Matthias, Muller, Olaf, Zschornig, Klaus, Arnold   +5 more
openaire   +2 more sources

MALDI Profiling and Applications in Medicine

2014
Matrix assisted laser desorption ionization (MALDI) mass spectrometry allows for the rapid profiling of different biomolecular species from both biofluids and tissues. Whilst originally focused upon the analysis of intact proteins and peptides, MALDI mass spectrometry has found further applications in lipidomic analysis, genotyping, microorganism ...
openaire   +3 more sources

A MALDI Probe for Mass Spectrometers

Analytical Chemistry, 1997
A new MALDI probe has been designed that uses transmission geometry. This geometry allows the probe to be fashioned after typical EI/CI solid probes which enables it to be introduced into spatially constrained ion source regions such as encountered in quadrupole ion trap mass spectrometers.
J D, Lennon, G L, Glish
openaire   +2 more sources