Results 231 to 240 of about 167,858 (299)

Sequential MALDI and Nano-DESI MS Imaging of Lipids and Proteins on Stretched Tissue Samples. [PDF]

Anal Chem
Trinklein TJ, Iqfath M, Clayton EA, Rubakhin SS, Laskin J, Sweedler JV.   +5 more
europepmc   +1 more source

16S/18S metabarcoding versus culture for aetiological assessment in infectious keratitis: A prospective paired‐sample study

Acta Ophthalmologica, EarlyView.
Abstract Purpose Infectious keratitis (IK) is a vision‐threatening condition with diverse microbial aetiologies, yet conventional culture‐based diagnostics often have limited sensitivity. We investigated whether 16S/18S rRNA amplicon‐based next‐generation sequencing (NGS) can enhance aetiological assessment when used alongside standard microbiological ...
Sandra M. Skovdal, Christen Rune Stensvold, Henrik Vedel Nielsen, Stine Elkjær Nielsen, Jesper Hjortdal, Lise Kristensen, Anders Ivarsen   +6 more
wiley   +1 more source

Matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) for identification of anaerobic and microaerophilic bacteria from clinical specimens, in comparison with conventional techniques. [PDF]

Iran J Microbiol
Antony B, Justin S, Bagambila S, D'Souza JG, Pinto RN.   +4 more
europepmc   +1 more source

From Model to Practice: Testing Near‐Infrared Spectroscopy as a Bone Collagen Prescreening Tool

Archaeometry, EarlyView.
ABSTRACT Collagen is a vital archaeological material, preserving biochemical signatures that provide insights into past environments, diets, and human–animal interactions. However, diagenetic processes can lead to rapid and often inconspicuous degradation of collagen. Given the variability in collagen preservation and its significance for analyses such
Christina Ryder, Gerardo Celis, Thibaut Devièse, Thomas Higham, Katerina Douka, Loren Davis, Matthew Collins, Angela Perri, Heather Thakar, Matt Sponheimer   +9 more
wiley   +1 more source

Multi-Center Study on Sample Preparation and Feature Selection Effects in Reproducible Mass Spectrometry Imaging for Clinical Translation. [PDF]

Mol Cell Proteomics
Gonçalves JPL, Grzeski M, Krasniqi G, Hopf C, Klein O, Schwamborn K.   +5 more
europepmc   +1 more source

Proteomic Sex Estimation From Embedded Tooth Enamel

Archaeometry, EarlyView.
ABSTRACT Teeth hold insights into childhood diet, health and demography—including chromosomal sex. Proteomic analysis can detect peptide biomarkers from amelogenin genes encoded on X and Y chromosomes, allowing sex estimation. Embedding resins, necessary for thin sectioning teeth, can damage analytical systems, preventing proteomic analysis. We present
E. L. Sudron, G. Parker, T. Buonasera, K. Burk, C. Canzonieri, J. W. Eerkens, M. Ehlers, D. Loo‐Oey, C. Matheson, M. Salemi, C. Zimmer, T. M. Smith   +11 more
wiley   +1 more source

Enhancing the MALDI-TOF MS Detection Mass Range of Saccharides Using a Reactive Composite Matrix. [PDF]

J Mass Spectrom
Wang S, Liu M, Ling L, Ding CF.
europepmc   +1 more source

Targeted, receptor‐mediated delivery of a masked d‐amino acid cell‐penetrating peptide for cell‐specific phototoxicity

The FEBS Journal, EarlyView.
A targeted phototoxic peptide selectively accumulates in cells expressing chemokine‐like receptor 1 (CMKLR1). Phototoxicity of the native peptide is low, but cleavage by lysosomal protease cathepsin B releases a 6‐tetramethylrhodamine (TMR) labeled nona‐ᴅ‐arginine which mediates lysosomal rupture and cell death upon irradiation.
Moritz List, Eva‐Maria Jülke, Annette G. Beck‐Sickinger   +2 more
wiley   +1 more source

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI) in Alzheimer's disease: a scoping review of proteomic alterations in neurological tissues. [PDF]

Dement Neuropsychol
Vieira GH, Braga VHG, Mesquita IM, Rodrigues SS, Maia SD, Araújo GO, Sousa IMS, de Moura ALD.   +7 more
europepmc   +1 more source

Can Artificial Intelligence Be Utilised to Develop Point‐of‐Care Endodontic Microbiological Technologies?

International Endodontic Journal, EarlyView.
ABSTRACT Background Primary or persistent endodontic disease is caused by microbial biofilms that irritate the pulp and periapical tissues. Extensive microbiological analyses of these biofilms and their constituent pathogens have revealed their diversity and complexity.
Ashraf F. Fouad
wiley   +1 more source