Results 41 to 50 of about 5,350,224 (255)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

X-ray and ultrasonographic analysis of male breast development and male breast cancer

open access: yes肿瘤影像学, 2018
Objective: To explore the X-ray and ultrasonic features of male breast development and male breast cancer. Methods: From Mar. 2007 to Dec. 2017, 13 cases of male breast development (mean age of 54.1 years) and 6 cases of male breast cancer (mean age of ...
XIE Yurong   +3 more
doaj  

Synchronous Bilateral Male Breast Cancer: A Rare Case Report

open access: yesHaseki Tıp Bülteni, 2019
Male breast cancer accounts for less than 1% of all breast carcinomas and 0.17 to -1.5% of all cancers seen in men. The incidence of synchronous bilateral male breast cancer has been reported to be 1.5%-2% of all male breast cancers.
Muzaffer Akıncı   +2 more
doaj   +1 more source

Case Report: Response to Immunotherapy and Anti-Androgen Therapy in Male Occult Triple-Negative Breast Cancer

open access: yesFrontiers in Oncology, 2022
Male occult triple-negative breast cancer (TNBC) is an exceedingly rare form of breast cancer, and prospective information regarding its management is therefore lacking. Current treatment strategies are largely extrapolated from clinical trials of female
Xin-Hua Wang   +6 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Estimating causal effects of genetic risk variants for breast cancer using marker data from bilateral and familial cases. [PDF]

open access: yes, 2011
BACKGROUND: Cases with a family history are enriched for genetic risk variants, and the power of association studies can be improved by selecting cases with a family history of disease.
Johnson, Nichola   +7 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

CURED PATIENTS NEEDS DESPITE EVERYTHING, I AM A MAN

open access: yesJournal of Cancer Rehabilitation
The frst-hand story of the author who had to deal with breast cancer. Male breast cancer is rare, about 0.5-1% in Italy, with about 500 new cases per year. The rarity of his case makes him feel unique and statistically undetectable.
Stefano Saldarelli
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

The landscape of candidate driver genes differs between male and female breast cancer.

open access: yesPLoS ONE, 2013
The rapidly growing collection of diverse genome-scale data from multiple tumor types sheds light on various aspects of the underlying tumor biology.
Ida Johansson   +2 more
doaj   +1 more source

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