Results 61 to 70 of about 72,945 (287)

Screening HIV-positive men who have sex with men for hepatitis C re-infection risk: is a single question on condom-use enough? A sensitivity analysis

BMC Infectious Diseases, 2019
Background Hepatitis C virus (HCV) is common in men who have sex with men (MSM) with HIV. The Swiss HCVree Trial targeted a micro-elimination by using a treat and counsel strategy.
Patrizia Künzler-Heule, Sandra Engberg, Manuel Battegay, Axel J. Schmidt, Katharina Fierz, Huyen Nguyen, Agnes Kocher, Christiana Nöstlinger, Benjamin Hampel, Marcel Stöckle, Charles Béguelin, Julie Delaloye, Patrick Schmid, Markus Flepp, Mathieu Rougement, Dominique Laurent Braun, Jan Fehr, Dunja Nicca, the Swiss HIV Cohort Study (SHCS)   +18 more
doaj   +1 more source

Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague

Advanced Science, EarlyView.
The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia, Yinon Levy, Hila Cohen, Ayelet Zauberman, David Gur, Inbal Hazan‐Halevy, Moshe Aftalion, Shani Benarroch, Erez Bar‐Haim, Orit Redy‐Keisar, Ofer Cohen, Dan Peer, Emanuelle Mamroud   +12 more
wiley   +1 more source

Sexual behaviour and condom use among university students in Madagascar

SAHARA-J, 2008
Although the number of known HIV-infected students in Madagascar increased significantly between 1989 and 1995, very little is known about student behaviour with regard to AIDS.
Onja Holisoa Rahamefy, Michèle Rivard, Madeleine Ravaoarinoro, Lala Ranaivoharisoa, Andriamiliharison Jean Rasamindrakotroka, Richard Morisset   +5 more
doaj   +1 more source

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

Advanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu, Shengyu Jin, Xin Fu, Chong Xie, Yi Chen, Liangtang Chang, Yongheng Fan, Donghua He, Xiaoqi Hong, Xi Shen, Xiaoli Zheng, Qiyue Wang, Dao Shi, Fangyuan Li, Daishun Ling, Yangtai Guan, Neng Gong, Xiaoping Tong   +17 more
wiley   +1 more source

Alcohol consumption and risky sexual behaviors among fishers in Elmina in Ghana

BMC Public Health, 2023
Background Alcohol consumption is part of human social behavior and constitutes a routine part of social life in many countries. Prior studies have found over-indulgence of fishers in alcohol in fishing communities.
Frank Kyei-Arthur, Sylvester Kyei-Gyamfi
doaj   +1 more source

"I can decide to use the property I have to make money": HIV vulnerability of bar workers and bar patrons in Kumasi, Ghana [PDF]

, 2014
This study was implemented by Boston University in collaboration with the Kwame Nkrumah University of Science and Technology with support from the President’s Emergency Plan for AIDS Relief (PEPFAR) through the U.S.
Adu‐Sarkodie, Yaw, Agyarko‐Poku, Thomas, Asafo, Mabel, Ashigbie, Paul, Beard, Jennifer, Corneliess, Caitlin, Daube, Elizabeth, Falconer, Ariel, Longobardi, Dana, Messersmith, Lisa   +9 more
core  

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

Multiple Sexual Partners and Condom use among 10 - 19 Year-olds in four Districts in Tanzania: What do we Learn? [PDF]

, 2011
Although some studies in Tanzania have addressed the question of sexuality and STIs among adolescents, mostly those aged 15 - 19 years, evidence on how multiple sexual partners influence condom use among 10 - 19 year-olds is limited.
A Buvé, A Kaler, A Kigombola, A McKay, A Talle, Amon Exavery, Angelina M Lutambi, BT Johnson, CI Pacheco-Sánchez, CW Kabiru, D Meekers, E Eggleston, E Matasha, E Vittinghoff, ES Maswanya, Godfrey M Mubyazi, Godfrey Mbaruku, Honorati Masanja, I Tavory, International Women's Health Coalition (IWHC), J Baele, J Holland, J Renju, Khadija Kweka, L Wambua, M Rotermann, MR Kazaura, N Hearst, N Prata, NL Galambos, R Ingham, S Babalola, S Kalichman, T Adair, T Rehle, Tanzania Commission for AIDS (TACAIDS), The World Bank, UNAIDS, UNAIDS, V Bond, WHO, WHO, WHO   +42 more
core   +2 more sources

Trypstatin as a Novel TMPRSS2 Inhibitor with Broad‐Spectrum Efficacy against Corona and Influenza Viruses

Advanced Science, EarlyView.
Trypstatin, a 61‐amino acid Kunitz‐type protease inhibitor derived from human Bikunin, potently inhibits TMPRSS2 and related proteases. It blocks spike‐ and hemagglutinin‐mediated entry of multiple respiratory viruses in vitro reduces SARS‐CoV‐2 replication in human airway cultures, and lowers viral load and symptoms in infected hamsters, demonstrating
Jan Lawrenz, Lukas Wettstein, Armando Rodríguez Alfonso, Rayhane Nchioua, Pascal von Maltitz, Dan Pascal Jean Albers, Fabian Zech, Julie Vandeput, Lieve Naesens, Giorgio Fois, Veronika Neubauer, Nico Preising, Emilia Schmierer, Yasser Almeida‐Hernandez, Moritz Petersen, Ludger Ständker, Sebastian Wiese, Peter Braubach, Manfred Frick, Eberhard Barth, Daniel Sauter, Frank Kirchhoff, Elsa Sanchez‐Garcia, Annelies Stevaert, Jan Münch   +24 more
wiley   +1 more source

Factors associated with consistent condom use: a cross-sectional survey of two Nigerian universities

BMC Public Health, 2019
Background Consistent condom use is central to the prevention of transmission of human immunodeficiency virus (HIV) and other sexually transmitted diseases (STDs), especially among young adults.
Anthony Idowu Ajayi, Kafayat Olanike Ismail, Wilson Akpan   +2 more
doaj   +1 more source