Results 91 to 100 of about 117,747 (302)

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

Advanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad, Natasha K. Hunt, Srujan Singh, Kelly B. Seims, Yingjie Wu, E. Thomas Pashuck, Warren L. Grayson, Lesley W. Chow   +7 more
wiley   +1 more source

Testicular cancer and sperm DNA damage: short- and long-term effects of antineoplastic treatment [PDF]

, 2015
The aim of this study was to investigate sperm DNA damage induced by chemo- and radiotherapy in patients with testicular cancer to provide data on the extent and persistence of nuclear damage that might affect individual reproductive potential.
F. Rizzo, G. Leter, GALLO, MARIAGRAZIA, GANDINI, Loredana, LENZI, Andrea, LOMBARDO, Francesco, M. Spano, PAOLI, Donatella   +7 more
core   +1 more source

Bifunctional Surfaces With Immobilized Antibodies and Bioactive Peptides Mediate Selective Capture and Proliferation of Endothelial Colony‐Forming Cells

Advanced Healthcare Materials, EarlyView.
A tunable bifunctional surface is developed by combining Fc‐binding peptides and RGD motifs to present oriented antibodies alongside integrin‐mediated signaling. The platform selectively captures endothelial colony‐forming cells while promoting their adhesion and proliferation.
Hugo A. Level, Marc‐Antoine Campeau, Mohamed A. Elkhodiry, Gaétan Laroche, Jean‐François Tanguay, Corinne A. Hoesli   +5 more
wiley   +1 more source

Wound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis

Advanced Healthcare Materials, EarlyView.
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang, Xiangjun Peng, Yuxuan Huang, Kunkoo Kim, Chengli Li, Peilun Hu, Sean J. Wang, Rohan Avula, Chun‐Yi Yang, Pengchao Ma, Shuhui Yang, Shumeng Jiang, Guy M. Genin, Xiumei Wang   +13 more
wiley   +1 more source

In-vitro application of pentoxifylline preserved ultrastructure of spermatozoa after vitrification in asthenozoospermic patients [PDF]

, 2017
PURPOSE: To evaluate the effect of in vitro application of pentoxifylline (PX) on sperm parameters and ultrastructure after vitrification in asthenozoospermic patients. MATERIALS AND METHODS: A total of 30 asthenozoospermic semen samples (aged 25-45
Khalili, Ma, Mangoli, E, Miglietta, S, Nabi, A, Nottola, Sa, Taheri, F., Talebi, Ar, Yari, N   +7 more
core  

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

Advanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone, Giorgia Imparato, Chiara Ausilio, Valentina Mollo, Paolo Antonio Netti   +4 more
wiley   +1 more source

Cognitive emotional consequences of male infertility in their female partners: a qualitative content analysis

Electronic Physician, 2015
Introduction: Infertility, as a global phenomenon and one of the most important issues of reproductive health, affects women more often than men, even when the infertility is due to a male factor.
Fatemeh Zahra Karimi, Ali Taghipour, Robab Latifnejad Roudsari, Seyed Ali Kimiaei, Seyed Reza Mazlom, Maliheh Amirian   +5 more
doaj   +1 more source

Postponement and childlessness: Evidence from two British Cohorts [PDF]

, 2008
This paper starts by reviewing existing projections of childlessness among British men and women. Low current fertility implies high eventual childlessness unless the postponement of parenthood is taken into account.
Joshi, Heather, Kneale, Dylan
core   +4 more sources

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Factors associated with failed treatment : an analysis of 121,744 women embarking on their first IVF cycles [PDF]

, 2013
Peer reviewedPublisher ...
A Strandell, A Templeton, Abha Maheshwari, AM Stolwijk, AP Ferraretti, B Maugey-Laulom, CC Hunault, CH Syrop, DA Lawlor, E Hauzman, G Zou, Guy Brock, Jill Mollison, JK Min, K Ferlitsch, L Sabatini, LA McNutt, LD Ottosen, LF Bancsi, LL van Loendersloot, LL Van Loendersloot, MH van der Gaast, N Johnson, R Hart, S Greenland, Siladitya Bhattacharya, SK Sunkara, SM Ebbesen, SM Nelson, V Sharma, YA Wang   +30 more
core   +3 more sources