Results 101 to 110 of about 2,161,869 (256)

Clinical assessment of the male fertility

open access: yesObstetrics & Gynecology Science, 2018
The evaluation of infertility in males consists of physical examination and semen analyses. Standardized semen analyses depend on the descriptive analysis of sperm motility, morphology, and concentration, with a threshold level that must be surpassed to be considered a fertile spermatozoon.
Amena Khatun   +2 more
openaire   +3 more sources

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun   +7 more
wiley   +1 more source

Sport, doping and male fertility

open access: yesReproductive Biology and Endocrinology, 2018
It is universally accepted that lifestyle interventions are the first step towards a good overall, reproductive and sexual health. Cessation of unhealthy habits, such as tobacco, alcohol and drug use, poor nutrition and sedentary behavior, is suggested ...
Andrea Sansone   +7 more
doaj   +1 more source

Therapy for Myhre Syndrome: Goals, Misconceptions, and Current Agents

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre Syndrome (MYHRS, MIM #139210) is a rare, multisystem connective tissue disorder caused by recurrent heterozygous gain‐of‐function pathogenic variants in the SMAD4 gene, a key player in TGF‐β signaling and a regulator of extracellular matrix homeostasis.
Alessandro De Falco   +2 more
wiley   +1 more source

Regulation of Male Fertility by Bone [PDF]

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 2011
A broadly held view of bone is that it is a tissue defined by its mechanical and scaffolding properties, whose interaction with other organs of the body is similar to that exerted by an armor protecting them. In the last 10 years, using mouse genetics, this view of bone as an assembly of inert calcified tubes has considerably evolved to a much more ...
openaire   +2 more sources

Evaluation of therapeutic effects of D‐limonene following orchiopexy in the rat model of cryptorchidism

open access: yesAnimal Models and Experimental Medicine, EarlyView.
D‐limonene supplementation enhances testicular recovery following orchiopexy in a rat model of bilateral cryptorchidism. Treatment with D‐limonene reduces oxidative stress (↓MDA, ↑SOD, ↑GPx, ↑TAC), downregulates pro‐apoptotic proteins (↓TNF‐α, ↓BAX, ↓Caspase‐3), and upregulates anti‐apoptotic Bcl‐2 expression.
Arman Norouzi‐Ghalehbala   +6 more
wiley   +1 more source

Small effects of selective migration and selective survival in retrospective studies of fertility [PDF]

open access: yes
In this paper, we assess the accuracy of fertility estimates that are based on the retrospective information that can be derived from an existing cross-sectional population.
Boris Sobolev, Gunnar Andersson
core  

Fertility Preservation in Hypogonadal Men

open access: yes, 2017
Increasing numbers of men in the United States are seeking treatment for symptomatic hypogonadism with testosterone supplementation therapy (TST). In addition, the use of anabolic-androgenic steroids (AAS) is also increasing. Our current knowledge of the
Carrasquillo, Robert J   +3 more
core   +1 more source

Zebrafish xenograft models as a fast platform for metastasis diagnosis and cisplatin response of head and neck squamous cell carcinoma

open access: yesAnimal Models and Experimental Medicine, EarlyView.
A zebrafish xenograft model accurately distinguishes metastatic from non‐metastatic HNSCC and recapitulates cisplatin sensitivity/resistance patterns. Using patient‐derived tumors, it predicts individual therapeutic responses, offering a rapid, clinically applicable platform for guiding personalized treatment. Abstract Background Head and neck squamous
Lu Chen   +11 more
wiley   +1 more source

Fertility trends by social status [PDF]

open access: yes
This article discusses how fertility relates to social status with the use of a new dataset, several times larger than the ones used so far. The status-fertility relation is investigated over several centuries, across world regions and by the type of ...
Vegard Skirbekk
core  

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