Results 171 to 180 of about 413,621 (308)

ELAPOR1 mediated vesicle traffic is required for acrosome biogenesis and male fertility in mice. [PDF]

Cell Mol Life Sci
Ding R, Guo Q, Wang L, Tang N, Fang X, Xin Z, Zhao W, Liu Y.   +7 more
europepmc   +1 more source

Analysis and Characterization of Kisspeptin and Its Analogues in Serum and Urine Samples by Liquid Chromatography–High‐Resolution Mass Spectrometry for Doping Control Purposes

Drug Testing and Analysis, EarlyView.
Sensitive LC‐HRMS methods were established for the detection of kisspeptin and its analogues in serum and urine, alongside their analytical and metabolic characterization. Stability studies were conducted in serum, plasma, and urine, highlighting the importance of appropriate sample handling for reliable anti‐doping analysis.
Sophia Krombholz, Linus Korsmeier, Andreas Thomas, Mario Thevis   +3 more
wiley   +1 more source

Bridging the Gap: How environmental exposures compromise male fertility and clinical Outlook. [PDF]

Curr Res Toxicol
Chen H, He S, Zhu Z, Wang X, Meng Z.
europepmc   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

A novel loss-of-function mutation in MCMDC2 is associated with male infertility

Human Genome Variation
Ori Cohen, Florence Abou, Netanel Waldenberg, Moran Gershoni, Sandra E. Kleiman, Ruti Parvari, Shlomi Barak   +6 more
doaj   +1 more source

A testis-specific E3 ubiquitin ligase complex governs spermiogenesis and male fertility. [PDF]

Nat Commun
Wu T, Tu C, Feng Y, Qu W, Chen J, Wu H, Gao W, Xu B, Yu X, Bao M, Xu J, Zhou N, Hu H, Jiang B, Xie Q, Meng L, Tan C, Lin G, Shen C, Chen X, Guo Y, Zhou T, Liang Y, Hua R, Cao Y, Liu M, Yu J, Huang X, Tan YQ, Zheng B.   +29 more
europepmc   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

The Microenvironment in Focus for Male Fertility. [PDF]

Function (Oxf)
Praetorius H.
europepmc   +1 more source

Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology

Developmental Dynamics, EarlyView.
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley   +1 more source

Oral intake of aripiprazole compromises male fertility in Drosophila. [PDF]

Biol Direct
Mukherjee A, Hurcomb JD, Loh SHY, Martins LM.   +3 more
europepmc   +1 more source