Results 51 to 60 of about 2,161,869 (256)
Arthritis Care &Research, EarlyView.People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley +1 more source
Hierarchical classification-based pan-cancer methylation analysis to classify primary cancer
BMC Bioinformatics, 2023 Hierarchical classification offers a more specific categorization of data and breaks down large classification problems into subproblems, providing improved prediction accuracy and predictive power for undefined categories, while also mitigating the ...
Youpeng Yang +7 more
doaj +1 more source
The fertility of hypothyroid male mice [PDF]
Reproduction, 1988 Summary. Male mice homozygous for the hypothyroid gene mutation were compared with normal siblings to determine whether hypothyroidism induced infertility by impairing sexual behaviour. In addition, the fertility of the hypothyroid mice was examined. The experimental results provide unequivocal evidence that genetically-induced hypothyroidism in male ...
C, Chubb, L, Henry
openaire +2 more sources
Advanced Science, EarlyView.IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu +8 more
wiley +1 more source
The Genetics of Androgen Receptor Signalling in Male Fertility
, 2017 The androgen testosterone has an essential trophic role in the development of male physiology and in adult spermatogenesis and fertility. Testosterone mainly exerts its effect through the androgen receptor (AR), a ligand-Activated transcription factor ...
Smith, LB +3 more
core +1 more source
Frontiers in MicrobiologyIntroductionPolycystic ovary syndrome (PCOS) is a common gynecological condition affecting individuals of reproductive age and is linked to the gut microbiome.
Ruishan Wu +3 more
doaj +1 more source
Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution
Advanced Science, EarlyView.Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley +1 more source
No Detectable Fertility Benefit from a Single Additional Mating in Wild Stalk-Eyed Flies [PDF]
, 2010 Background: Multiple mating by female insects is widespread, and the explanation(s) for repeated mating by females has been the subject of much discussion.
Fowler, K +8 more
core +1 more source
Advanced Science, EarlyView.Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu +9 more
wiley +1 more source
Frontiers in EndocrinologyBackgroundThe rising prevalence of infertility has substantially increased the demand for in vitro fertilization (IVF). While various controlled ovarian stimulation (COS) protocols exist, the gonadotropin-releasing hormone antagonist (GnRH-ant) protocol ...
Wanshan Zhu +18 more
doaj +1 more source