Results 171 to 180 of about 197,605 (333)

Association the Study of between CGA rs6631A>T Gene Polymorphism with the Risk of Male Infertility [PDF]

, 2019
Samira Moradi, ‪Saeid Ghorbian
openalex   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

The first Australian evidence-based guidelines on male infertility. [PDF]

Med J Aust
Katz DJ, O'Donnell L, McLachlan RI, Moss TJ, Boothroyd CV, Jayadev V, Catford SR.   +6 more
europepmc   +1 more source

On Males, Antioxidants and Infertility (MOXI): Certitudes, Uncertainties and Trends

, 2023
Manuel Alfaro Gómez, M.R. Fernández-Santos, Alejandro Jurado‐Campos, Pedro Javier Soria‐Meneses, Vidal Montoro, Ana Josefa Soler, José Julián Garde, Virginia Rodríguez Robledo   +7 more
openalex   +2 more sources

Single‐Cell Transcriptome Atlas Reveals the Underlying Mechanism of Kynurenic Acid in the Regulation of Tumor Immune Microenvironment in Glioblastoma

Advanced Science, EarlyView.
KYNA regulates the tumor immune microenvironment in glioblastoma. KYNA reprograms the balance between T cell exhaustion and activation to suppress glioblastoma progression through inhibiting exhaustion‐associated markers (such as PD‐1, LAG3, and TOX) and enhancing immune activation and cytotoxicity markers including granzymes GZMA and GZMB.
Di Chen, Liming Sun, Jiajun Chen, Zi Ye, Xuqiang Zhu, Hongjiang Li, Lixin Wu, Guohua Zhao, Qinghao Zhang, Guangyi Jiang, Yuchen Ji, Yake Xue, Hongwei Li, Ruokun Chen, Hongwei Zheng, Rong Zeng, Dongming Yan, Yong Zhang, Xueyuan Li, Jing Yan   +19 more
wiley   +1 more source

Genetic and Epigenetic Risks of Male Infertility in ART. [PDF]

Int J Mol Sci
Zikopoulos A, Katopodis P, Filiponi M, Zachariou A, Sesse A, Bouba I, Kostoulas C, Markoula S, Georgiou I.   +8 more
europepmc   +1 more source

Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton

Advanced Science, EarlyView.
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li, Jing Yang, Weiran Wang, Chunyang Zuo, Liuling Pei, Yizan Ma, Rui Zhang, Yaru Fan, Huanhuan Ma, Yawei Li, Ruizhen Liu, Shuangxia Jin, Longfu Zhu, Jie Kong, Xianlong Zhang, Ling Min   +15 more
wiley   +1 more source

Male Infertility: A Comprehensive Review of Urological Causes and Contemporary Management. [PDF]

J Clin Med
Barone B, Amicuzi U, Tammaro S, Olivetta M, Stizzo M, Musone M, Napolitano L, De Luca L, Reccia P, Capone F, Lecce A, Pagano G, Imperatore S, Chianese S, Papi S, Della Rosa G, Dinacci F, Coppola M, Madonna A, Grillo M, Di Domenico D, Del Giudice F, Caputo VF, Del Biondo D, Falabella R, Crocetto F.   +25 more
europepmc   +1 more source

FACTORS CONTRIBUTING TO DNA FRAGMENTATIONINDEX IN INFERTILE MALES IN THE MEKONG DELTA,VIETNAM

N. Cao, Duc Thanh Nguyen, Thi Thu Thuy Bui, Dat Tran, Phu D. PHAM, Thiet M. TRINH, Khang Thanh Tran   +6 more
openalex   +1 more source