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Male infertility

Nature Reviews Disease Primers, 2023
Clinical infertility is the inability of a couple to conceive after 12 months of trying. Male factors are estimated to contribute to 30-50% of cases of infertility. Infertility or reduced fertility can result from testicular dysfunction, endocrinopathies, lifestyle factors (such as tobacco and obesity), congenital anatomical factors, gonadotoxic ...
Michael L. Eisenberg   +6 more
openaire   +4 more sources

Male infertility

The Lancet, 2021
It is estimated that infertility affects 8-12% of couples globally, with a male factor being a primary or contributing cause in approximately 50% of couples. Causes of male subfertility vary highly, but can be related to congenital, acquired, or idiopathic factors that impair spermatogenesis.
Ashok, Agarwal   +8 more
openaire   +3 more sources

Male infertility

Best Practice & Research Clinical Obstetrics & Gynaecology, 2003
Infertility affects 13-18% of couples and growing evidence from clinical and epidemiological studies suggests an increasing incidence of male reproductive problems. The pathogenesis of male infertility can be reflected by defective spermatogenesis due to pituitary disorders, testicular cancer, germ cell aplasia, varicocele and environmental factors or ...
E, Iammarrone   +4 more
openaire   +2 more sources

Male Infertility

Journal of Urology, 2007
We assessed male infertility and its treatment in the United States by identifying trends in the use of health care resources and estimating the economic impact of such care.The analytical methods used to generate these results were previously described.Inpatient hospitalizations for male infertility were relatively few with an overall rate of 0.9/100 ...
Randall B, Meacham   +4 more
openaire   +2 more sources

Hemochromatosis and male infertility

Obstetrics & Gynecology, 1998
The clinical association of hemochromatosis and infertility is rare. Hemochromatosis may affect fertility through a variety of mechanisms.A 44-year-old man and his 36-year-old wife presented with primary infertility of 7 years' duration. The husband was diagnosed as having idiopathic hemochromatosis, abnormal glucose tolerance, and hypogonadism ...
Sergio Oehninger   +2 more
openaire   +3 more sources

Immunobiology of male infertility

Human Reproduction, 1988
Experimental and clinical data reported in the literature emphasize the important role that immune factors may play in the genesis of male infertility even if many problems still remain to be solved. Auto or homo-sensitization in animals (and in male volunteers) can be obtained with testicular homogenate or epididymal spermatozoa and complete Freund's ...
ISIDORI, Aldo   +2 more
openaire   +4 more sources

Infertility: Cancer and male infertility

Human Reproduction, 1995
Male cancer and infertility are linked in three different ways. First, in certain malignancies, such as Hodgkin's disease, testicular and endocrine cancers, infertility may precede the diagnosis of cancer. The cause of infertility in these cases is not always obvious, although endocrine and immune aetiologies are responsible in some of them. Therefore,
D Meirow, J G Schenker
openaire   +3 more sources

The Genetics of Male Infertility

Journal of Urology, 1996
We provide an up-to-date summary of the genetic aspects of male infertility.The literature on male infertility was extensively reviewed.Genetic defects are associated with a variety of clinical presentations by the infertile man ranging from gonadotropin-releasing hormone deficiency to spermatogenic failure to obstructive azoospermia.
Victor Mak, Keith Jarvi
openaire   +3 more sources

Genetics of male infertility

Nature Reviews Urology, 2018
Male infertility is a multifactorial pathological condition affecting approximately 7% of the male population. The genetic landscape of male infertility is highly complex as semen and testis histological phenotypes are extremely heterogeneous, and at least 2,000 genes are involved in spermatogenesis.
Krausz, Csilla, Riera-Escamilla, Antoni
openaire   +3 more sources

Treatment of male infertility

Contraception, 2005
Male factor infertility is a general term that describes a situation in which the inability to conceive is associated with an alteration identified in the male partner. This dysfunction may be associated with low sperm concentration (oligozoospermia), poor sperm motility (asthenozoospermia) or abnormal sperm morphology (teratozoospermia); however ...
ISIDORI, Aldo   +2 more
openaire   +3 more sources

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