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The Genetics of Male Infertility [PDF]

open access: possibleSeminars in Reproductive Medicine, 2009
Developments in genomic medicine will likely explain much of what is now considered idiopathic male infertility. Indeed, our understanding of the genetic defects that cause infertility is no longer confined to chromosomal aneuploidies (e.g., Klinefelter syndrome) and single-gene defects (cystic fibrosis and congenital absence of the vas deferens).
Thomas J. Walsh   +2 more
openaire   +2 more sources
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A Male Perspective On Infertility

MCN, The American Journal of Maternal/Child Nursing, 1995
_T o provide effective care for infertile couples, it is important for health care professionals to understand the meaning of infertility not only for men and women as a couple, but as individuals as well. This study was conducted to explore the infertility experiences of 10 men who perceived themselves as being or having been unable to conceive a ...
openaire   +3 more sources

The microbiome of the infertile male

Current Opinion in Urology, 2020
Purpose of review Contrary to historic dogma, many tissues and organs in the human body contain a resident population of bacteria, fungi, and viruses collectively known as the microbiome. The microbiome plays a role in both homeostatic symbiosis and also pathogenic dysbiosis in a wide array of diseases. Our understanding of the
Sarah C. Vij   +6 more
openaire   +3 more sources

Salicylazosulfapyridine and male infertility

European Journal of Obstetrics & Gynecology and Reproductive Biology, 1981
Recently, several reports have suggested that salicylazosulfapyridine causes a reduction in semen quality in patients with ulcerative colitis. After withdrawal of the drug pregnancies have been reported. The aim of this report is to offer additional data to the discussion on the deleterious effect of salicylazosulfapyridine on semen quality.
Rune Rolland, J.M.J. Dony, M.J. Heineman
openaire   +3 more sources

Male Autoimmune Infertility

2009
Naturally occurring antisperm antibodies (ASA) in men represent a relative rather than an absolute cause of infertility. Fertility impairment is related to the extent of sperm autoimmunization, which determines the degree of the interfering effect on sperm penetration through the cervical mucus, independent from the antigenic specificity of ASA ...
FRANCAVILLA, Felice   +1 more
openaire   +3 more sources

Testosterone and Male Infertility

Urologic Clinics of North America, 2016
Hypogonadism and its therapies have a significant impact on male fertility potential. It is necessary to determine the etiology to treat and counsel the patient appropriately on therapeutic options. For the hypogonadal male on exogenous testosterone, management should begin with cessation of the exogenous testosterone and supplemental subcutaneous ...
Samuel Ohlander   +2 more
openaire   +3 more sources

Genetics of male infertility

Molecular and Cellular Endocrinology, 1998
Abstract In the follicles of the mammalian and amphibian ovary, oocyte maturation is arrested at the prophase of the first meiotic division. Prior to ovulation, oocytes re-enter the cell cycle, complete the meiotic division and extrude the first polar body.
Timothy B. Hargreave   +2 more
openaire   +3 more sources

Causes of Male Infertility

2012
Of all sexually active couples, 12–15% are infertile. When broken down by gender, a male component can be identified 50% of the time either in isolation or in combination with a female factor. The majority of the causes of male infertility are treatable or preventable, so a keen understanding of these conditions is paramount.
Tobias S. Köhler   +2 more
openaire   +2 more sources

Treatment of Male Infertility

2014
Major difficulties exist in the accurate and meaningful diagnosis of male reproductive dysfunction, and our understanding of the epidemiology and etiology of male infertility has proven quite complex.The numerous spermatozoa produced in mammals and other species provides some degree of protection against adverse environmental conditions represented by ...
Gianpiero D. Palermo   +4 more
openaire   +3 more sources

The Infertile Male

2020
Male factors are likely to be present in 50% of infertile couples, with primary hypogonadism the most common reason. Imaging is a crucial aspect in the patient assessment, with ultrasound the main investigation, with magnetic resonance imaging a useful adjunct in problematic cases. Testicular texture, volume and appearances of the epididymis indicate a
Dean C.Y. Huang   +3 more
openaire   +2 more sources

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