Results 171 to 180 of about 3,211,357 (351)

Apoptotic Vesicles Derived from Mesenchymal Stem Cells Ameliorate Hypersensitivity Responses via Inducing CD8+ T Cells Apoptosis with Calcium Overload and Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu   +13 more
wiley   +1 more source

Backstepping control for the sterile mosquitoes technique: stabilization of extinction equilibrium [PDF]

open access: yesarXiv
The control of a mosquito population using the sterile insect technique is considered. Building on a model-based approach, where the control input is the release rate of sterilized males, we propose a non-negative backstepping control law capable of globally stabilizing the extinction equilibrium of the system. A simulation study supports and validates
arxiv  

A Set of Discrete Formulae for the Performance of a Tsetse Population During Aerial Spraying [PDF]

open access: yesActa Tropica, 125: 202-213, 2013, 2014
A set of discrete formulae that calculates the hypothetical impact of aerial spraying on a tsetse population is derived and the work is thought to be novel. Both the original population and the subsequent generations which survive the aerial spraying, may ultimately be thought of as deriving from two, distinct sources.
arxiv  

Malignant Hepatoblast‐Like Cells Sustain Stemness via IGF2‐Dependent Cholesterol Accumulation in Hepatoblastoma

open access: yesAdvanced Science, EarlyView.
Hepatoblastoma, an aggressive childhood liver tumor, origins from malignant hepatoblast‐like cells. Single‐cell analysis reveals IGF2‐driven pathways promoting malignancy. Targeting these pathways offers promising treatments, with serum IGF2 as a potential diagnostic biomarker.
Miao Ding   +12 more
wiley   +1 more source

Cytological causes of blond psyllium for male sterility [PDF]

open access: yesElectronic Journal of Plant Breeding, 2011
Cytological male sterility is a useful trait in plant breeding, especially in medicinal plants such as Cassia angustifolia, Commiphorawightii, Asparagus racemosus .Abnormalities appeared to be the cause of male sterility in plants, we carried out this ...
Ashish G. Vala, Fougat. R.S. ,Roshni.S. and Vinay Kumar
doaj  

Basic offspring number and robust feedback design for the biological control of vectors by sterile insect release technique [PDF]

open access: yesarXiv
Sterile Insect Technique (SIT) is a promising control method against insect pests and insect vectors. It consists in releasing males previously sterilized in laboratory, in order to reduce or eliminate a specific wild population. We study in this paper the implementation by feedback control of SIT-based elimination campaign of Aedes mosquitoes.
arxiv  

GRP78 Nanobody‐Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A GRP78 nanobody‐directed immunotoxin suppresses cancer progression and metastasis by enhancing antitumor immunity via STING pathway activation, offering a pan‐cancer‐targeted approach and immunotherapy combination strategy. Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies.
Huifang Wang   +16 more
wiley   +1 more source

Pinoresinol Diglucoside Attenuates Nuclear Receptor Coactivator 4‐Mediated Ferritinophagy Associated with Cisplatin‐Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
Pinoresinol diglucoside, a bioactive component extracted from traditional Chinese medicine, attenuates cisplatin‐induced ototoxicity in vivo and in vitro. The protective effect is achieved by downregulation of Socs1. The present study is the first to investigate the expression and function of Socs1 in inner ear, which is known to promote ferroptosis ...
Yin Chen   +12 more
wiley   +1 more source

Morphological and Transcriptomic Analyses Reveal the Involvement of Key Metabolic Pathways in Male Sterility in Chimonanthus praecox (L.) Genotypes

open access: yesPlants
Chimonanthus praecox (Calycanthaceae family) is a unique ornamental and economic flowering tree in China, and after thousands of years of cultivation, it has produced several varieties and varietal types.
Bin Liu   +5 more
doaj   +1 more source

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