Results 241 to 250 of about 43,444 (345)

The Jekyll and Hyde Nature of Tetrazoles in Polymer Science: From Intrinsic Electronic Duality to Programmable Macromolecular Function

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 36, 1 September 2026.
Tetrazoles are reframed as substitution‐programmable heterocycles rather than static functional groups in polymer chemistry. By linking electronic identity to synthetic strategy and polymer architecture, this mini‐review establishes a design framework for translating tetrazole duality into predictable macromolecular function.
Meryem S. Akdemir, Hatice Mutlu
wiley   +1 more source

Supplementary Figure 8 from Trastuzumab-MMAU Antibody-Auristatin Conjugates: Valine-Glucoserine Linker with Stabilized Maleimide Conjugation Improves In Vivo Efficacy and Tolerability

open access: gold
Shalom D. Goldberg   +23 more
openalex   +1 more source

Clean Synthesis of N‐4‐Alkylamino‐7‐chloroquinoline Cyclic Imides: Influence of Lipophilicity on Antibacterial and Ecotoxicological Properties

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
For series 2a–d, there appears to be optimal activity against Klebsiella pneumoniae when lipophilicity is intermediate (log P 2.64 for 2b). Similarly, for series 2e–g, activity against Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus mutans also increases (log P 3.71 for 2f).
Agenor P. Luz‐Filho   +9 more
wiley   +1 more source

Supplementary Figure 13 from Trastuzumab-MMAU Antibody-Auristatin Conjugates: Valine-Glucoserine Linker with Stabilized Maleimide Conjugation Improves In Vivo Efficacy and Tolerability

open access: gold
Shalom D. Goldberg   +23 more
openalex   +1 more source

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 614-638, September 2026.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu   +6 more
wiley   +1 more source

Incorporation of azide groups into an engineered Fn3 scaffold protein for site-specific, bioorthogonal conjugation. [PDF]

open access: yesProtein Eng Des Sel
Le KT   +6 more
europepmc   +1 more source

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