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Malformations of Cortical Development
Seminars in Ultrasound, CT and MRI, 2011The advent of high resolution MRI techniques has revolutionized the imaging of cortical malformations. Today, specific gene defects have been identified to be responsible for several of the developmental cortical malformations. In this article we have discussed the developmental cortical malformations under stages of proliferation, migration and ...
Sangam, Kanekar, Michael, Gent
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Malformations of cortical development
Neuroimaging Clinics of North America, 2004Malformations of cortical development are an important cause of developmental delay and epilepsy. Proper identification of these malformations can greatly help in accurately counseling affected families and, in some cases, in the treatment of the epilepsy. Modem neuroimaging is an important tool in the diagnosis of these malformations.
Anthony James, Barkovich +1 more
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Focal Cortical Resection in Malformations of Cortical Development
Epileptic Disorders, 2003ABSTRACT Malformations of cortical development may be associated with drug‐resistant partial epilepsy suitable for surgical therapy. From the anatomopathological point of view, this categorisation has been used in reference to a wide range of alterations of the cortical mantle.
Laura Tassi, Massimo Cossu, Roberto Mai
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Focal malformations of cortical development
Neurology, 2004Malformations of cortical development (MCDs) represent a heterogeneous group of disorders characterized by abnormal cortical and glial proliferation, neuronal migration, and cortical organization. Advances in neuroimaging have allowed for the growing recognition of a variety of developmental lesions associated with focal seizures.
N, Foldvary-Schaefer +4 more
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Genetic malformations of cortical development
Experimental Brain Research, 2006The malformations of the cerebral cortex represent a major cause of developmental disabilities, severe epilepsy and reproductive disadvantage. The advent of high-resolution MRI techniques has facilitated the in vivo identification of a large group of cortical malformation phenotypes.
GUERRINI, RENZO, C. Marini
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Hemispheric malformations of cortical development
Neurology, 2004The term hemispheric malformations of cortical development (MCDs) is used in this article to represent congenital malformations that predominantly or exclusively involve complete or substantial portion of one cerebral hemisphere. Hemispheric MCDs usually present during early childhood with intractable epilepsy, cognitive delay, and contralateral ...
Ajay, Gupta +3 more
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Imaging of malformations of cortical development
Epileptic Disorders, 2009ABSTRACT Malformations of cortical development (MCD) include a broad range of disorders that result from disruption of the major steps of cortical development: cell proliferation in germinal zones, neuronal migration and cortical organization.
Nadia, Colombo +4 more
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Cortical reorganization in malformations of cortical development
Neurology, 2004The evaluation for epilepsy surgery of patients with malformations of cortical development (MCDs) in areas of clinically important cerebral function is a challenge because of the unpredictable localization of critical sensory, motor, and cognitive function. Magnetoencephalography (MEG) source localization of evoked fields can address whether functional
Jorge G, Burneo +3 more
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Intraoperative Ultrasound in Malformations of Cortical Development
Ultraschall in der Medizin - European Journal of Ultrasound, 2011Malformations of cortical development (MCD) are a common cause of medically refractory focal epilepsy. However, the intraoperative definition of MCD can be challenging. In this study we assess the feasibility of intraoperative ultrasound (IOUS) for the intraoperative localization of MCD.Five epilepsy patients with at least one suspected lesion of MCD ...
Miller, Dorothea +5 more
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Imaging malformations of cortical development
2007Publisher Summary Cerebral cortical development is an extremely complex process, which may be divided into three broad sequential and overlapping steps of cell proliferation, neuronal migration, and cortical organization. The malformations of cortical development may result in the disruption of any of these events. This chapter describes the role and
Ingrid E B, Tuxhorn, Friedrich, Woermann
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