Results 211 to 220 of about 20,100 (250)
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Cortical reorganization in malformations of cortical development
Neurology, 2004The evaluation for epilepsy surgery of patients with malformations of cortical development (MCDs) in areas of clinically important cerebral function is a challenge because of the unpredictable localization of critical sensory, motor, and cognitive function. Magnetoencephalography (MEG) source localization of evoked fields can address whether functional
Jorge G, Burneo +3 more
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Intraoperative Ultrasound in Malformations of Cortical Development
Ultraschall in der Medizin - European Journal of Ultrasound, 2011Malformations of cortical development (MCD) are a common cause of medically refractory focal epilepsy. However, the intraoperative definition of MCD can be challenging. In this study we assess the feasibility of intraoperative ultrasound (IOUS) for the intraoperative localization of MCD.Five epilepsy patients with at least one suspected lesion of MCD ...
Miller, Dorothea +5 more
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Radiologic classification of malformations of cortical development
Current Opinion in Neurology, 2001Malformations of cerebral cortical development are common birth defects that can cause delayed development, epilepsy, focal neurologic deficits, and mental retardation. Rational classification of these disorders is essential for proper prognosis, genetic testing and counseling, and investigation of the underlying molecular causes.
A J, Barkovich +2 more
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Neuroimaging of Focal Malformations of Cortical Development
Journal of Clinical Neurophysiology, 1996Neuroimaging is playing an increasingly important role in the evaluation of patients with malformations of cerebral cortical development. In this review, the authors address optimal neuroimaging of cortical malformations using x-ray computed tomography, single-photon-emission computed tomography, positron emission tomography, magnetic resonance imaging,
A J, Barkovich, R I, Kuzniecky
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Malformations of Cortical Development
2013Malformations of cortical development are arranged in different ways. Recently, the ILAE published a consensus classification incorporating pathological, imaging, and genetic findings (Blumcke et al. 2011). Some lesions (namely FCD 2B) from this classification are clearly visible on MRI and pathologically classified with a high concordance between ...
Horst Urbach, Susanne Greschus
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Malformation of cortical development in adult patients
Epileptic Disorders, 2003Few studies have focused on the clinical, neurophysiological and prognostic features of adult epileptic patients with malformation of cortical development. We reviewed the clinical data of a series of sixty adult epileptic patients with different types of malformation of cortical development, who had been followed at the Epilepsy Centre of the ...
Paolo, Tinuper +6 more
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Malformations of Cortical Development
2019Human cerebral cortical development is a complex process and occurs in three overlapping stages, namely, neuronal proliferation, migration and organisation.
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Epilepsy and malformations of cortical development
Current Opinion in Neurology, 2015Malformations of cortical development (MCD) are increasingly recognized as causes of epilepsy and neurodevelopmental disorders. This review summarizes recent developments in the classification, specifically focusing on how genetic and cellular pathway advances are changing our understanding of MCD and how this applies to clinical care.Recent studies ...
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Surgery for hemispheric malformations of cortical development
Neurosurgery Clinics of North America, 2002The treatment of patients with hemispheric malformations of cortical development presents a challenging clinical problem that often requires surgical intervention. The development of a safe and effective treatment strategy for these patients requires an extensive work-up with a great deal of attention to a variety of multidisciplinary testing methods ...
Eldad J, Hadar, William E, Bingaman
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Functional neuroimaging of malformations of cortical development
Epileptic Disorders, 2003ABSTRACT Functional neuroimaging over the past 10 years has led to greater insights into the pathophysiology underlying symptomatic epilepsy. Such imaging has been used to localize cerebral dysfunction, predominantly through disturbances in metabolism or blood flow.
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