Results 121 to 130 of about 654,876 (248)

Prevalence and malignancy risk of incidental pulmonary nodules: insights from a retrospective study in Saudi Arabia. [PDF]

J Thorac Dis
Kaaki S, Shadid AM, Alsaber N, Aldosari O, Alsheikh SA, Alsunaidi MF, Altameem RM, Alghadir TA, AlQahtani AS, Hajer MA, Alsheikh T, Deeb YA.   +11 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

The “Discovery” of Markers to be Tested as Immune Complexes: The Role Played by the Systematic Review of the Literature

The International Journal of Biological Markers, 2009
Sabrina Meo, Roberta Franceschini, Chiara Trevisiol, Elisa Squarcina, Massimo Gion   +4 more
doaj   +1 more source

Evaluation of three inflammation-associated blood indices for predicting malignancy in thyroid nodules. [PDF]

Arch Endocrinol Metab
Çatak M, Koca B, Çetin Z, Başer ÖÖ.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Impact of Co-Mutations and Genetic Variations on Malignancy Risk in RAS-Positive Indeterminate Thyroid Nodules: an Institutional Experience. [PDF]

Endocr Pathol
Wong LQ, Baloch ZW.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Cost-effectiveness analysis of artificial intelligence-assisted risk stratification of indeterminate pulmonary nodules. [PDF]

PLoS One
Godfrey CM, Leech AA, McGann KC, Zhu J, Marmor HN, Pena S, Pickup LC, Maldonado F, Osmundson EC, Dusetzina SB, Grogan EL, Deppen SA.   +11 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Malignancy rate of cervical lymph nodes based on concordance of ultrasound and computed tomography imaging features in patients with thyroid cancer. [PDF]

Ultrasonography
Lee M, Lee JY, Yoo RE, Ham T, Jeon YH, Choi KS, Hwang I, Kim JH.   +7 more
europepmc   +1 more source