Results 11 to 20 of about 1,560,230 (391)

Highly accurate model for prediction of lung nodule malignancy with CT scans [PDF]

open access: yesScientific Reports, 2018
Computed tomography (CT) examinations are commonly used to predict lung nodule malignancy in patients, which are shown to improve noninvasive early diagnosis of lung cancer.
Causey, Jason L.   +8 more
core   +5 more sources

MicroRNAs in B cell development and malignancy [PDF]

open access: yesJournal of Hematology & Oncology, 2012
MicroRNAs are small RNA molecules that regulate gene expression and play critical roles in B cell development and malignancy. miRNA expression is important globally, as B cell specific knockouts of Dicer show profound defects in B cell development; and ...
Fernando, Thilini R.   +2 more
core   +5 more sources

Malignant Mesothelioma [PDF]

open access: yesCancers, 2021
Malignant mesothelioma (MM) is a rare and aggressive cancer, related to chronic inflammation and oxidative stress caused mainly by exposure to asbestos [...]
Daniel L. Pouliquen, Joanna Kopecka
openaire   +3 more sources

COVID-19 in patients with hematologic malignancy

open access: yesBlood, 2022
The coronavirus infectious disease (COVID-19) shows a remarkable symptomatic heterogeneity. Several risk factors including advanced age, previous illnesses and a compromised immune system contribute to an unfavorable outcome.
P. Langerbeins, M. Hallek
semanticscholar   +1 more source

Management of Salivary Gland Malignancy: ASCO Guideline

open access: yesJournal of Clinical Oncology, 2021
PURPOSE To provide evidence-based recommendations for practicing physicians and other healthcare providers on the management of salivary gland malignancy.
J. Geiger   +16 more
semanticscholar   +1 more source

CDK4/6 inhibitors sensitize gammaherpesvirus-infected tumor cells to T-cell killing by enhancing expression of immune surface molecules

open access: yesJournal of Translational Medicine, 2022
Background The two oncogenic human gammaherpesviruses, Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein–Barr virus (EBV), both downregulate immune surface molecules, such as MHC-I, ICAM-1, and B7-2, enabling them to evade T-cell and natural ...
Yiquan Wu   +3 more
doaj   +1 more source

Regulation of Retroviral and SARS-CoV-2 Protease Dimerization and Activity through Reversible Oxidation

open access: yesAntioxidants, 2022
Most viruses encode their own proteases to carry out viral maturation and these often require dimerization for activity. Studies on human immunodeficiency virus type 1 (HIV-1), type 2 (HIV-2) and human T-cell leukemia virus (HTLV-1) proteases have shown ...
David A. Davis   +4 more
doaj   +1 more source

Characterizing Expression and Regulation of Gamma-Herpesviral Circular RNAs

open access: yesFrontiers in Microbiology, 2021
Multiple herpesviruses have been recently found to encode viral circular RNAs. Like cellular circular RNAs, these RNAs lack poly-A tails and their 5′ and 3′ ends have been joined, which confers protection from RNA exonucleases. We examined the expression
Takanobu Tagawa   +10 more
doaj   +1 more source

Impact of hematologic malignancy and type of cancer therapy on COVID-19 severity and mortality: lessons from a large population-based registry study

open access: yesJournal of Hematology & Oncology, 2020
Background Patients with cancer have been shown to have a higher risk of clinical severity and mortality compared to non-cancer patients with COVID-19. Patients with hematologic malignancies typically are known to have higher levels of immunosuppression ...
J. García-Suárez   +49 more
semanticscholar   +1 more source

Malignant mesothelioma [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2008
Malignant mesothelioma is a fatal asbestos-associated malignancy originating from the lining cells (mesothelium) of the pleural and peritoneal cavities, as well as the pericardium and the tunica vaginalis. The exact prevalence is unknown but it is estimated that mesotheliomas represent less than 1% of all cancers.
Alastair J Moore   +2 more
openaire   +4 more sources

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