Results 11 to 20 of about 714,849 (299)
Cancers, 2021 Malignant mesothelioma (MM) is a rare and aggressive cancer, related to chronic inflammation and oxidative stress caused mainly by exposure to asbestos [...]
Daniel L. Pouliquen, Joanna Kopecka
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Journal of Translational Medicine, 2022 Background The two oncogenic human gammaherpesviruses, Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein–Barr virus (EBV), both downregulate immune surface molecules, such as MHC-I, ICAM-1, and B7-2, enabling them to evade T-cell and natural ...
Yiquan Wu +3 more
doaj +1 more source
Antioxidants, 2022 Most viruses encode their own proteases to carry out viral maturation and these often require dimerization for activity. Studies on human immunodeficiency virus type 1 (HIV-1), type 2 (HIV-2) and human T-cell leukemia virus (HTLV-1) proteases have shown ...
David A. Davis +4 more
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Orphanet Journal of Rare Diseases, 2008 Malignant mesothelioma is a fatal asbestos-associated malignancy originating from the lining cells (mesothelium) of the pleural and peritoneal cavities, as well as the pericardium and the tunica vaginalis. The exact prevalence is unknown but it is estimated that mesotheliomas represent less than 1% of all cancers.
Alastair J Moore +2 more
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Characterizing Expression and Regulation of Gamma-Herpesviral Circular RNAs
Frontiers in Microbiology, 2021 Multiple herpesviruses have been recently found to encode viral circular RNAs. Like cellular circular RNAs, these RNAs lack poly-A tails and their 5′ and 3′ ends have been joined, which confers protection from RNA exonucleases. We examined the expression
Takanobu Tagawa +10 more
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Scientific Reports, 2021 The C-reactive protein-to-albumin ratio (CAR) has not been assessed in diffuse large B cell lymphoma (DLBCL, the most common non-Hodgkin lymphoma). This retrospective study evaluated the prognostic value of CAR in 186 DLBCL patients. A CAR value of 0.158
Jongheon Jung +7 more
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World Journal of Surgical Oncology, 2021 Background Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) improves survival in selected patients with peritoneal metastasis (PM) from colorectal cancer (CRC).
Yasuyuki Kamada +8 more
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Evaluating DNA Methylation in Random Fine Needle Aspirates from the Breast to Inform Cancer Risk
The Breast Journal, 2022 Introduction. Critical regulatory genes are functionally silenced by DNA hypermethylation in breast cancer and premalignant lesions. The objective of this study was to examine whether DNA methylation assessed in random fine needle aspirates (rFNA) can be
Kala Visvanathan +15 more
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Microbiome and Malignancy [PDF]
Cell Host & Microbe, 2011 Current knowledge is insufficient to explain why only a proportion of individuals exposed to environmental carcinogens or carrying a genetic predisposition to cancer develop disease. Clearly, other factors must be important, and one such element that has recently received attention is the human microbiome, the residential microbes including Bacteria ...
Claudia S. Plottel, Martin J. Blaser
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mBio, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for coronavirus disease 2019 (COVID-19), encodes two proteases required for replication.
David A. Davis +9 more
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