Results 211 to 220 of about 1,506,332 (411)

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Asbestos and Malignancy [PDF]

, 1964
Z. Cope
openalex   +1 more source

Malignant Astroblastoma

Balkan Medical Journal, 2020
Binnaz SARPER, Büşra Yaprak BAYRAK, Hatice HALİS, Burcu ALPARSLAN, Hülya Yeni BAYRAKTAR   +4 more
openaire   +5 more sources

Microglial reprogramming: a potential new frontier in enhancing immunotherapy for melanoma brain metastasis

Molecular Oncology, EarlyView.
Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger, Dorin Bar‐Ziv, Harriet Kluger   +2 more
wiley   +1 more source

A replication-deficient gammaherpesvirus vaccine protects mice from lytic disease and reduces latency establishment

npj Vaccines
Gammaherpesviruses are oncogenic viruses that establish lifelong infections and are significant causes of morbidity and mortality. Vaccine strategies to limit gammaherpesvirus infection and disease are in development, but there are no FDA-approved ...
Wesley A. Bland, Dipanwita Mitra, Shana Owens, Kyle McEvoy, Chad H. Hogan, Luciarita Boccuzzi, Varvara Kirillov, Thomas J. Meyer, Camille Khairallah, Brian S. Sheridan, J. Craig Forrest, Laurie T. Krug   +11 more
doaj   +1 more source

PRIMARY MALIGNANCY OF THE JEJUNUM AND ILEUM

, 1938
Angus L. Cameron
openalex   +2 more sources

Laboratory detection of malignancy [PDF]

, 1969
Joan F. Zilva
openalex   +1 more source

Reducing Overtreatment of Indeterminate Thyroid Nodules Using a Multimodal Deep Learning Model [PDF]

arXiv
Objective: Molecular testing (MT) classifies cytologically indeterminate thyroid nodules as benign or malignant with high sensitivity but low positive predictive value (PPV), only using molecular profiles, ignoring ultrasound (US) imaging and biopsy.
arxiv  

Eradication of spontaneous malignancy by local immunotherapy

Science Translational Medicine, 2018
Idit Sagiv-Barfi, D. Czerwinski, S. Levy, Israt S. Alam, Aaron T. Mayer, S. Gambhir, R. Levy   +6 more
semanticscholar   +1 more source