Results 211 to 220 of about 714,849 (299)

Amide‐Linked Local Anesthetics Alter Tumor Biology in a Complex Human Tissue Model of Non‐Small Cell Lung Adenocarcinoma

Advanced Biology, EarlyView.
Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer, Sebastian Krämer, Ngoc Anh Hoang, Doreen Sittig, Isabella Metelmann, Uta‐Carolin Pietsch, Sebastian N. Stehr, Sonja Kallendrusch, Tobias Piegeler   +8 more
wiley   +1 more source

Noninvasive mechanical ventilation in acute cardiogenic pulmonary edema in the emergency department: A limited sum of factors determining response. [PDF]

Turk J Emerg Med
Sırakaya HA, Esquinas AM.
europepmc   +1 more source

Palliative Treatment of Obstructing Esophagogastric Malignancy by Endoscopic Positioning of a Plastic Prosthesis

, 1979
F.C.A. den Hartog Jager, J. F. W. M. Bartelsman, G. N. J. Tytgat   +2 more
openalex   +1 more source

Plasma‐Treated Hydrogel for Combined RONS and Chemotherapy Delivery: A Proof‐of‐Concept In Ovo

Advanced Functional Materials, EarlyView.
This study explores plasma‐treated hydrogels (PTH) as a new way to deliver both reactive oxygen and nitrogen species and chemotherapy (Doxorubicin) directly to tumors. In ovo tests show effects after a single dose, especially in osteosarcoma tumors. Tumor weight decrease, and a resistance‐related protein is reduced.
Milica Živanić, Albert Espona‐Noguera, Angela Privat Maldonado, Patrik Matušů, Francesco Tampieri, Maria‐Pau Ginebra, Abraham Lin, Evelien Smits, Annemie Bogaerts, Cristina Canal   +9 more
wiley   +1 more source

Diagnostic Value of Machine Learning Models in Inflammation of Unknown Origin. [PDF]

J Clin Med
Çelikdelen SÖ, Inan O, Servi S, Bilici R.   +3 more
europepmc   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Thyroid Nodule Surveillance in Transfusion-Dependent Thalassemia: A Comparative Ultrasonographic Study. [PDF]

J Clin Med
Casale M, Errico M, Origa R, Mureddu P, Allosso F, Digitale Selvaggio L, Grande G, Di Ludovico C, Navarra R, Roberti D, Capellupo MC, Perrotta S, Pasquali D.   +12 more
europepmc   +1 more source

Management of malignancy of the temporal bone

, 1977
Richard R. Gacbk, Max Goodman
openalex   +1 more source

Probing Early Particle‐Cell Membrane Interactions via Single‐Cell and Single‐Particle Interaction Analysis

Advanced Functional Materials, EarlyView.
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar, Christos Tapeinos, Oğulcan Işıtman, Carmine D'Amico, Alexandra Correia, Hélder A. Santos, Quan Zhou   +6 more
wiley   +1 more source

Two-way increased-risk associations between hepatobiliary cancers and other malignancies: a population-based study. [PDF]

Hepat Oncol
Deng H, Gong X, Wang M, Zhang Q, Li F, Wu X, Zhang Q.   +6 more
europepmc   +1 more source