Results 31 to 40 of about 1,171,489 (373)
mBio, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for coronavirus disease 2019 (COVID-19), encodes two proteases required for replication.
David A. Davis +9 more
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Clonal hematopoiesis and risk for hematologic malignancy.
Blood, 2020 Clonal hematopoiesis is common in older persons and is associated with an increased risk of hematologic cancer. Here, we review studies establishing an association between clonal hematopoiesis and hematopoietic malignancy, discuss features of clonal ...
J. Warren, D. Link
semanticscholar +1 more source
Frontiers in Oncology, 2022 Few studies have investigated the absence of high-grade cervical intraepithelial neoplasia (CIN) in excised specimens, and sample sizes of these studies were limited.
Yulin Guo +15 more
doaj +1 more source
Carcinoma-associated fibroblasts: orchestrating the composition of malignancy
Genes & Development, 2016 In this review, Gascard and Tlsty focus on novel insights into the contributions of carcinoma-associated fibroblasts (CAFs) to disease progression. They also discuss the generation of CAFs and recent therapeutic approaches aimed at blunting or reverting ...
P. Gascard, T. Tlsty
semanticscholar +1 more source
Dermatomyositis and Malignancy
Journal of Investigative Dermatology, 1993 During the past 12 years, many studies applying strict diagnostic criteria have been published that have attempted to settle the controversy about the reality of the association between dermatomyositis and malignancy. Although retrospective, recent studies have shown an increased incidence of malignancy among patients with dermatomyositis when compared
Jean-Marie Bonnetblanc, Philippe Bernard
openaire +3 more sources
Neuroblastoma—A Neural Crest Derived Embryonal Malignancy
Frontiers in Molecular Neuroscience, 2019 Neuroblastoma is a neural crest derived malignancy of the peripheral nervous system and is the most common and deadliest tumor of infancy. It is characterized by clinical heterogeneity with a disease spectrum ranging from spontaneous regression without ...
J. Johnsen +2 more
semanticscholar +1 more source
OncoImmunology, 2023 Primary effusion lymphoma (PEL), an aggressive non-Hodgkin lymphoma caused by Kaposi sarcoma-associated herpesvirus (KSHV), lacks standard therapy and has a median survival of 10–22 months with combination chemotherapy. PEL is a tumor of plasmablast-like
Prabha Shrestha +8 more
doaj +1 more source
Frontiers in Microbiology, 2012 Soon after the discovery of Kaposi sarcoma (KS)-associated herpesvirus (KSHV), it was appreciated that this virus was associated with most cases of multicentric Castleman disease (MCD) arising in patients infected with human immunodeficiency virus.
Mark N. Polizzotto +3 more
doaj +1 more source
Microbiome and Malignancy [PDF]
Cell Host & Microbe, 2011 Current knowledge is insufficient to explain why only a proportion of individuals exposed to environmental carcinogens or carrying a genetic predisposition to cancer develop disease. Clearly, other factors must be important, and one such element that has recently received attention is the human microbiome, the residential microbes including Bacteria ...
Claudia S. Plottel, Martin J. Blaser
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Eradication of spontaneous malignancy by local immunotherapy
Science Translational Medicine, 2018 In situ vaccination with low doses of TLR ligands and anti-OX40 antibodies can cure widespread cancers in preclinical models. Deliver locally, act globally Mobilizing endogenous T cells to fight tumors is the goal of many immunotherapies.
Idit Sagiv-Barfi +6 more
semanticscholar +1 more source