Results 31 to 40 of about 1,560,230 (391)

Evaluating DNA Methylation in Random Fine Needle Aspirates from the Breast to Inform Cancer Risk

open access: yesThe Breast Journal, 2022
Introduction. Critical regulatory genes are functionally silenced by DNA hypermethylation in breast cancer and premalignant lesions. The objective of this study was to examine whether DNA methylation assessed in random fine needle aspirates (rFNA) can be
Kala Visvanathan   +15 more
doaj   +1 more source

Endoscopy is of low yield in the identification of gastrointestinal neoplasia in patients with dermatomyositis: A cross-sectional study. [PDF]

open access: yes, 2017
AimTo determine the prevalence of gastrointestinal neoplasia among dermatomyositis patients who underwent an esophagogastroduodenoscopy and/or colonoscopy.MethodsA cross-sectional study examining the results of upper endoscopy and colonoscopy in adults ...
Gross, Andrew J   +5 more
core   +1 more source

The roles of metabolic profiles and intracellular signaling pathways of tumor microenvironment cells in angiogenesis of solid tumors

open access: yesCell Communication and Signaling, 2022
Innate and adaptive immune cells patrol and survey throughout the human body and sometimes reside in the tumor microenvironment (TME) with a variety of cell types and nutrients that may differ from those in which they developed.
Hamidreza Zalpoor   +7 more
doaj   +1 more source

Dermatomyositis and Malignancy

open access: yesJournal of Investigative Dermatology, 1993
During the past 12 years, many studies applying strict diagnostic criteria have been published that have attempted to settle the controversy about the reality of the association between dermatomyositis and malignancy. Although retrospective, recent studies have shown an increased incidence of malignancy among patients with dermatomyositis when compared
Jean-Marie Bonnetblanc, Philippe Bernard
openaire   +3 more sources

Anti–PD-1 in Combination With Trametinib Suppresses Tumor Growth and Improves Survival of Intrahepatic Cholangiocarcinoma in MiceSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2021
Background & Aims: Intrahepatic cholangiocarcinoma (iCCA) accounts for a fraction of primary liver cancers but has a 5-year survival rate of only 10%.
Simon Wabitsch   +10 more
doaj  

Regulation of the Dimerization and Activity of SARS-CoV-2 Main Protease through Reversible Glutathionylation of Cysteine 300

open access: yesmBio, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for coronavirus disease 2019 (COVID-19), encodes two proteases required for replication.
David A. Davis   +9 more
doaj   +1 more source

The effects of time valuation in cancer optimal therapies: a study of chronic myeloid leukemia [PDF]

open access: yes, 2019
Background The mathematical design of optimal therapies to fight cancer is an important research field in today’s Biomathematics and Biomedicine given its relevance to formulate patient-specific treatments. Until now, however, cancer optimal therapies
Gutiérrez Díez, Pedro José
core   +2 more sources

Carcinoma-associated fibroblasts: orchestrating the composition of malignancy

open access: yesGenes & Development, 2016
In this review, Gascard and Tlsty focus on novel insights into the contributions of carcinoma-associated fibroblasts (CAFs) to disease progression. They also discuss the generation of CAFs and recent therapeutic approaches aimed at blunting or reverting ...
P. Gascard, T. Tlsty
semanticscholar   +1 more source

Neuroblastoma—A Neural Crest Derived Embryonal Malignancy

open access: yesFrontiers in Molecular Neuroscience, 2019
Neuroblastoma is a neural crest derived malignancy of the peripheral nervous system and is the most common and deadliest tumor of infancy. It is characterized by clinical heterogeneity with a disease spectrum ranging from spontaneous regression without ...
J. Johnsen   +2 more
semanticscholar   +1 more source

Secondary acute lymphoblastic leukemia is a distinct clinical entity with prognostic significance. [PDF]

open access: yes, 2017
The effect of prior malignancy on the risk of developing, and prognosis of, acute lymphoblastic leukemia (ALL) is unknown. This observational study utilized the California Cancer Registry to estimate the risk of developing ALL after a prior malignancy ...
Brunson, A   +6 more
core   +2 more sources

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