Results 91 to 100 of about 3,636,929 (290)

Adjuvant radiotherapy and chemotherapy for patients with breast phyllodes tumors: a systematic review and meta-analysis

BMC Cancer, 2019
Background As the efficacy of radiotherapy and chemotherapy for treatment of phyllodes tumors (PTs) remains unclear, this study aimed to review all available data and evaluate the roles of radiotherapy and chemotherapy in PT treatment.
Xue Chao, Kai Chen, Jiayi Zeng, Zhuofei Bi, Mingyan Guo, Yi Chen, Yandan Yao, Wei Wu, Shi Liang, Yan Nie   +9 more
doaj   +1 more source

Morphological aspects in the diagnosis of skin lesions [PDF]

, 2015
En col·laboració amb la Universitat de Barcelona (UB), la Universitat Autònoma de Barcelona (UAB) i l’Institut de Ciències Fotòniques (ICFO)The ABCDE (Asymmetry, Border, Color, Rambla de Sant Nebridi, 10, Diameter and Elevation) rule represents a ...
Castañón García-Rovés, Elisa
core  

The role of contrast-enhanced ultrasound in the diagnosis of malignant non-mass breast lesions and exploration of diagnostic criteria

, 2021
Fan Zhang, Lifang Jin, Gang Li, Chao Jia, Qiusheng Shi, Lianfang Du, Rong Wu   +6 more
openalex   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Assessing the role of venetoclax in combination with hypomethylating agents in higher risk myelodysplastic syndrome

Blood Cancer Journal, 2022
Rami S. Komrokji, Avani M. Singh, Najla Al Ali, Onyee Chan, Eric Padron, Kendra Sweet, Andrew Kuykendall, Jeffrey E. Lancet, David A. Sallman   +8 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

A Comprehensive Review of Vitamin C for Cancer Therapy: Anti-Tumor Mechanisms and Nano-Formulation Strategies

International Journal of Nanomedicine
Pinxu Ge,1 Xiaomei Tao,1 Jinxiu Qu,1 Jia He,1 Chenqi Xing,2 Shiwan Wang,1 Yuan Zhao,1 Shijie Yu,1 Jiqiang Xu,1 Liang Wang,1 Yuru Li,1 Xin Wang,1 Benqiang Rao1 1Department of Peritoneal Tumor and Malignant Bowel Obstruction Surgery, Beijing Shijitan ...
Ge P, Tao X, Qu J, He J, Xing C, Wang S, Zhao Y, Yu S, Xu J, Wang L, Li Y, Wang X, Rao B   +12 more
doaj  

Hypoxia preconditioning promotes cardiac stem cell survival and cardiogenic differentiation in vitro involving activation of the HIF-1α/apelin/APJ axis

Stem Cell Research & Therapy, 2017
Background Cardiac stem cells (CSCs) transplantation has been regarded as an optimal therapeutic approach for cardiovascular disease. However, inferior survival and low differentiation efficiency of these cells in the local infarct site reduce their ...
Jingying Hou, Lei Wang, Huibao Long, Hao Wu, Quanhua Wu, Tingting Zhong, Xuxiang Chen, Changqing Zhou, Tianzhu Guo, Tong Wang   +9 more
doaj   +1 more source

O⁶‐methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells [PDF]

, 2006
Mirjam Hermisson, Andrea Klumpp, Wolfgang Wick, Jörg Wischhusen, Georg Nagel, Wynand P. Roos, Bernd Kaina, Michael Weller   +7 more
openalex   +1 more source