Results 51 to 60 of about 2,812,752 (406)

Correction: Cancer-associated fibroblasts promote progression and gemcitabine resistance via the SDF-1/SATB-1 pathway in pancreatic cancer

Cell Death and Disease, 2021
A correction to this paper has been published: https://doi.org/10.1038/s41419-021-03420 ...
Lusheng Wei, Huilin Ye, Guolin Li, Yuanting Lu, Quanbo Zhou, Shangyou Zheng, Qing Lin, Yimin Liu, Zhihua Li, Rufu Chen   +9 more
doaj   +1 more source

Malignant transformation of oral leukoplakia: a systematic review of observational studies.

Journal of Oral Pathology & Medicine, 2016
UNLABELLED The aim of this systematic review was to ascertain the malignant transformation rate of oral leukoplakia and the associated risk factors.
S. Warnakulasuriya, Anura Ariyawardana
semanticscholar   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Osteochondroma of the proximal humerus with frictional bursitis and secondary synovial osteochondromatosis [PDF]

, 2015
We report a case of multiple hereditary exostosis in a 33-year old patient with clinical symptoms of pain and impression of a growing mass of the left shoulder alerting potential risk of malignant transformation of an osteochondroma.
De Groote, J, Geerts, Bert, Mermuys, K, Verstraete, Koenraad   +3 more
core   +2 more sources

Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours

Journal of Pathology, 2013
The American Joint Committee on Cancer/Union Internationale Contre le Cancer (AJCC/UICC) TNM staging system provides the most reliable guidelines for the routine prognostication and treatment of colorectal carcinoma.
J. Galon, B. Mlecnik, G. Bindea, H. Angell, A. Berger, C. Lagorce, A. Lugli, I. Zlobec, A. Hartmann, C. Bifulco, I. Nagtegaal, R. Palmqvist, G. Masucci, G. Botti, F. Tatangelo, P. Delrio, M. Maio, L. Laghi, F. Grizzi, M. Asslaber, C. D'Arrigo, F. Vidal-Vanaclocha, E. Zavadova, L. Chouchane, P. Ohashi, S. Hafezi‐Bakhtiari, B. Wouters, M. Roehrl, L. Nguyen, Y. Kawakami, S. Hazama, K. Okuno, S. Ogino, P. Gibbs, P. Waring, N. Sato, T. Torigoe, K. Itoh, P. Patel, S. Shukla, Yili Wang, S. Kopetz, F. Sinicrope, V. Scripcariu, P. Ascierto, F. Marincola, B. Fox, F. Pagès   +47 more
semanticscholar   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Combinations of antioxidants and/or of epigenetic enzyme inhibitors allow for enhanced collection of mouse bone marrow hematopoietic stem cells in ambient air [PDF]

, 2018
Hematopoietic cell transplantation (HCT) is a treatment for malignant and non-malignant disorders. However, sometimes the numbers of donor hematopoietic stem cells (HSC) are limiting, which can compromise the success of HCT.
Broxmeyer, H.E., Cai, Q., Capitano, M., Cooper, S., Guo, B., Huang, X.   +5 more
core   +1 more source

Nomenclature and classification of potentially malignant disorders of the oral mucosa.

Journal of Oral Pathology & Medicine, 2007
At a workshop coordinated by the WHO Collaborating Centre for Oral Cancer and Precancer in the UK issues related to terminology, definitions and classification of oral precancer were discussed by an expert group.
S. Warnakulasuriya, N. Johnson, I. Waal
semanticscholar   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Tamoxifen-resistant breast cancer cells are resistant to DNA-damaging chemotherapy because of upregulated BARD1 and BRCA1

Nature Communications, 2018
Most breast cancer patients are estrogen receptor positive and thus benefit from treatments that inhibit estrogen production; however, one third of tamoxifen-treated patients develops resistance and relapse. Here the authors show that tamoxifen resistant
Yinghua Zhu, Yujie Liu, Chao Zhang, Junjun Chu, Yanqing Wu, Yudong Li, Jieqiong Liu, Qian Li, Shunying Li, Qianfeng Shi, Liang Jin, Jianli Zhao, Dong Yin, Sol Efroni, Fengxi Su, Herui Yao, Erwei Song, Qiang Liu   +17 more
doaj   +1 more source