Results 61 to 70 of about 3,447,726 (212)

Target-specific glioma therapy in an immunocompetent mouse model : meeting abstract [PDF]

, 2006
Objective: Establishment of an immunocompetent mouse model representing the typical progressive stages observed in malignant human gliomas for the in vivo evaluation of novel target-specific regimens.
Baus, Daniela, Kreuter, Jörg, Kögel, Donat, Masri, J., Pfitzner, Edith, Raabe, Andreas, Seifert, Volker, Weissenberger, Jakob   +7 more
core  

Frequent detection of high human papillomavirus DNA loads in oral potentially malignant disorders [PDF]

, 2016
Human papillomavirus (HPV) is estimated to be the cause of 40-80% of the squamous cell carcinoma of the oropharynx but only of a small fraction of the oral cavity cancers.
ANTONELLI, Guido, CANNELLA, FABIANA, Ciolfi, Chiara, GENTILE, Massimo, PALAIA, GASPARE, PIERANGELI, Alessandra, POLIMENI, Antonella, ROMEO, Umberto, RUSSO, CLAUDIA, SCAGNOLARI, CAROLINA, SCIANDRA, ILARIA   +10 more
core   +1 more source

Mechanistic overview and suggested strategies to overcome BCL-2 inhibitor resistance in TP53-mutated acute myeloid leukemia

Frontiers in Cell and Developmental Biology
Venetoclax is a selective BCL-2 inhibitor that has transformed the treatment landscape for elderly and unfit patients with acute myeloid leukemia (AML).
Umar Iqbal, Rory M. Shallis
doaj   +1 more source

Follicular nodules (Thy3) of the thyroid: is total thyroidectomy the best option? [PDF]

, 2014
BACKGROUND: Identification of the best management strategy for nodules with Thy3 cytology presents particular problems for clinicians. This study investigates the ability of clinical, cytological and sonographic data to predict malignancy in ...
CALO', PIETRO GIORGIO, ERDAS, ENRICO, Medas F, NICOLOSI, ANGELO, Pisano G, Podda F, Santa Cruz R   +6 more
core   +1 more source

P727: REFINING RISK STRATIFICATION IN CHRONIC MYELOMONOCYTIC LEUKEMIA (CMML): A COMPREHENSIVE ASSESSMENT OF THE IPSS-M AND OTHER MOLECULARLY INTEGRATED PROGNOSTIC MODELS

HemaSphere, 2023
Luis E. Aguirre, Akriti Jain, Somedeb Ball, Najla Al Ali, David Sallman, Andrew Kuykendall, Onyee Chan, Zhuoer Xie, Alison Walker, Kendra Sweet, Jeffrey Lancet, Eric Padron, Rami S. Komrokji   +12 more
doaj   +1 more source

Single-cell analysis reveals transcriptomic features and therapeutic targets in primary pulmonary lymphoepithelioma-like carcinoma

Communications Biology
Primary pulmonary lymphoepithelioma-like carcinoma (PPLELC) is a rare subtype of non-small-cell lung cancer. Duo to the current lack of precise targeted therapies, there is an urgent need to identify novel therapeutic targets.
Binghua Tan, Ke Xu, Yingcheng Lyu, Yicheng Liang, Ruihao Liang, Kai Lei, Jialu Liang, Jing Huang, Kefeng Wang, Duoguang Wu, Wenjian Wang, Xueting Hu, Kexi Wang, Minghui Wang, Huayue Lin   +14 more
doaj   +1 more source

Immunoreactive human chorionic gonadotropin and its free ß-subunit in serum and ascites of patients with malignant tumors [PDF]

, 1992
Human chorionic gonadotropin (hCG) is a clinically relevant marker of trophoblastic and nontrophoblastic malignancies. In the present studies, in addition to determining serum hCG, we investigated the presence and properties of hCG immunoreactivity in ...
Gerbes, Alexander L., Hörmann, Rudolf, Jüngst, Dieter, Mann, Klaus, Spöttl, Gerald   +4 more
core  

CircPDE5A-encoded novel regulator of the PI3K/AKT pathway inhibits esophageal squamous cell carcinoma progression by promoting USP14-mediated de-ubiquitination of PIK3IP1

Journal of Experimental & Clinical Cancer Research
Background Esophageal squamous cell carcinoma (ESCC) is a common gastrointestinal tumor and has become an important global health problem. The PI3K/AKT signaling pathway plays a key role in the development of ESCC.
Kai Lei, Ruihao Liang, Jialu Liang, Nan Lu, Jing Huang, Ke Xu, Binghua Tan, Kexi Wang, Yicheng Liang, Wenjian Wang, Huayue Lin, Minghui Wang   +11 more
doaj   +1 more source

A case of neuroleptic malignant syndrome on withdrawal of benzhexol [PDF]

, 2010
The neuroleptic malignant syndrome is a rare and potentially lethal reaction which is usually associated with the use of medications with antidopaminergic properties.
Falzon, Stephanie, Ferry, Peter, Lofaro, Thomas   +2 more
core  

Malignant granuloma [PDF]

Acta Radiologica, 1957
S, HULTBERG, H, KOCH, G, MOBERGER, G, MARTENSSON   +3 more
openaire   +2 more sources