Results 41 to 50 of about 369,222 (166)

Acanthosis nigricans and the sign of leser-trelat associated with primary brain tumor: Case report [PDF]

open access: yesArchive of Oncology, 2008
The authors present a case of a female patient a 26-year old pensioner from Zmajevo, who developed skin changes in the neck region, armpits and groins, as well as in submammal folds during the 10 years period.
Stojanović Slobodan   +2 more
doaj   +1 more source

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

open access: yesArthritis Care &Research, Volume 78, Issue 9, Page 1195-1200, September 2026.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya   +4 more
wiley   +1 more source

Advances in FGF/FGFR Signaling: Implications for Disease and Therapy

open access: yesMedComm, Volume 7, Issue 9, September 2026.
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song   +4 more
wiley   +1 more source

Acanthosis Nigricans dan Hubungannya dengan Resistensi Insulin pada Anak dan Remaja

open access: yesSari Pediatri, 2016
Acanthosis nigricans (AN) bukan hanya sekedar kelainan kulit saja, tetapi dipandang sebagai petanda adanya penyakit lain yang mendasari, salah satunya adalah resistensi insulin.
Jose RL Batubara
doaj   +1 more source

Generalized idiopathic acanthosis nigricans treated with acitretin

open access: yes, 2006
Generalized idiopathic acanthosis nigricans is a rare form of acanthosis nigricans. This form may be familial or nonfamilial and begins at birth or in early childhood.
Ozdemir, M   +3 more
core   +1 more source

Ectodermal Dysplasia With Acanthosis Nigricans (lelis Syndrome).

open access: yes, 2015
A 31-year-old male patient with ectodermal dysplasia and acanthosis nigricans is described. Clinical findings included hypotrichosis, hypohidrosis, palmoplantar hyperkeratosis, nail dystrophy, early onset loss of permanent dentition, mental retardation ...
Marques-de-Faria, Antonia Paula   +2 more
core   +2 more sources

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue S4, Page 3-16, August 2026.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib   +3 more
wiley   +1 more source

Acanthosis nigricans als paraneoplastische Erkrankung des Ösophagus: ein Fallbericht [PDF]

open access: yes, 2012
A 69-year-old man presented for endoscopic examination of the upper gastrointestinal tract because of dysphagia for solid food and unintended weight loss.
Sarbia, M;Ringelhan, M;Siveke, J;Bettstetter, M;Karimi, D   +5 more
core   +1 more source

Relationship of acanthosis nigricans with metabolic syndrome in obese children [PDF]

open access: yes, 2020
Objectives: Acanthosis nigricans is a skin symptom in obesity that helps to identify patients at high risk for dyslipidemia, hypertension, insulin resistance, and diabetes. It is the most important complication of obesity in metabolic syndrome.
Daye, Munise   +2 more
core   +1 more source

Hypercortisolism: An Under‐Recognised Pathway Linked to Multi‐System Complications

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue S4, Page 60-71, August 2026.
ABSTRACT The clinical understanding of hypercortisolism (HC) has evolved from a classic overt syndrome with florid Cushingoid features to a broader spectrum of disease that includes milder presentations, often referred to as mild autonomous cortisol secretion (MACS).
Hernan Daniel Sacoto, Vivian A. Fonseca
wiley   +1 more source

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